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    SYSTEM FOR CUMULATIVE IMAGING OF BIOLOGICAL SAMPLES
    1.
    发明申请
    SYSTEM FOR CUMULATIVE IMAGING OF BIOLOGICAL SAMPLES 审中-公开

    公开(公告)号：WO2023044017A1

    公开(公告)日：2023-03-23

    申请号：PCT/US2022/043821

    申请日：2022-09-16

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： THRUSH, Evan ,  SWIHART, Stephen ,  MCDONALD, Kevin

    IPC: H04N23/10 ,  G16B20/00

    Abstract: Aspects of the present disclosure relate to systems and methods for generating a composite image. This can include a western blot imager with a real time camera. One aspect of the present disclosure relates to an imaging system. The imaging system includes a sample plane that can receive and hold a sample, a photon resolving camera, and a lens attached to the photon resolving camera, the photon resolving camera and the lens positioned to image the sample plane.

    SATURATION AVOIDANCE IN DIGITAL IMAGING
    2.
    发明申请
    SATURATION AVOIDANCE IN DIGITAL IMAGING 审中-公开

    公开(公告)号：WO2020081330A1

    公开(公告)日：2020-04-23

    申请号：PCT/US2019/055455

    申请日：2019-10-09

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： GRIFFIN, Michael ,  SWIHART, Stephen

    IPC: G06T5/50 ,  G06T7/10 ,  G06T7/11 ,  G06T7/136 ,  G06T7/174 ,  G06T7/187 ,  G06T7/194 ,  G06T7/80 ,  G06T7/90

    Abstract: A method of image capture helps avoid saturation in digital imaging. In one implementation, the method includes capturing a first digital image of a target using an electronic array light sensor, and identifying one or more saturated pixels in the first digital image. The method further includes identifying a region of interest in the first digital image, the region of interest encompassing the one or more identified saturated pixels. The method also includes capturing a second digital image of the target using the electronic array light sensor. The second digital image encompasses only the region of interest, and the second digital image is captured with a shorter exposure time than the first digital image. The first and second digital images may be combined into a high dynamic range image. Systems for digital imaging may be based on complementary metal oxide semiconductor (CMOS) or charge coupled device (CCD) sensors.

    ILLUMINATOR SYSTEMS HAVING LIGHT EMITTING DIODES WITH UV ACTIVATION
    3.
    发明申请
    ILLUMINATOR SYSTEMS HAVING LIGHT EMITTING DIODES WITH UV ACTIVATION 审中-公开

    公开(公告)号：WO2021231205A1

    公开(公告)日：2021-11-18

    申请号：PCT/US2021/031267

    申请日：2021-05-07

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： SWIHART, Stephen ,  THRUSH, Evan ,  MCDONALD, Kevin

    IPC: G01N33/53 ,  G01N21/00 ,  G01N21/17 ,  G01N21/33 ,  G01N21/64 ,  G01N27/447

    Abstract: An imaging system including an illuminator apparatus or an epi-illumination apparatus that has LEDs for illuminations is provided for stain-free gel activation and fluorescent sample visualization. The illuminator apparatus includes a housing, a light source array disposed on at least one side surface of the housing and including at least one plurality of LEDs having each LED individually operable to output light of a predetermined color within a range of wavelengths, and a controller for controlling ranges of operational parameters of the at least one plurality of LEDs. The light emitted from the light source array incidents upon a sample having a gel that includes a product of UV light induced reaction between tryptophan and a haloalkane and the light emitted from the light source array includes ultraviolet (UV) light to excite a fluorescent response of the sample.

    ELECTRONIC COMPONENT ASSEMBLY WITH THERMALLY CONDUCTIVE STRUCTURES FOR IMAGE SENSORS
    4.
    发明申请
    ELECTRONIC COMPONENT ASSEMBLY WITH THERMALLY CONDUCTIVE STRUCTURES FOR IMAGE SENSORS 审中-公开

    公开(公告)号：WO2021113240A1

    公开(公告)日：2021-06-10

    申请号：PCT/US2020/062706

    申请日：2020-12-01

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： SWIHART, Stephen ,  LU, Li ,  JAMESON, Wade ,  THRUSH, Evan ,  GRIFFIN, Michael ,  PEREZ, Evelio

    IPC: H01L27/146

    Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.

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