中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

5 records (took 0.024 seconds)

    ELECTROPHORESIS APPARATUS WITH MINIMAL AUTOFLUORESCENCE TO ENABLE GEL PROCESSING IN SITU
    1.
    发明申请
    ELECTROPHORESIS APPARATUS WITH MINIMAL AUTOFLUORESCENCE TO ENABLE GEL PROCESSING IN SITU 审中-公开

    公开(公告)号：WO2022026476A1

    公开(公告)日：2022-02-03

    申请号：PCT/US2021/043328

    申请日：2021-07-27

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： THRUSH, Evan ,  SWIHART, Stephen L. ,  MCDONALD, Kevin Alan

    IPC: G01N27/447

    Abstract: An electrophoresis apparatus with minimal autofluorescence to enable gel processing in situ, and methods of making and using the electrophoresis apparatus. An exemplary electrophoresis apparatus may comprise a cassette defining a cavity between a first pane and a second pane of a double-paned viewing window, and also may comprise a slab gel located in the cavity. The viewing window may be transparent to ultraviolet light that drives a derivatization reaction in the slab gel, and, absent the slab gel, may define a window autofluorescence inducible by irradiation with the ultraviolet light. The window autofluorescence, per unit area, may be less than five-fold a gel autofluorescence of the slab gel, per the same unit area and under the same irradiation with the ultraviolet light.

    FLUORESCENCE DETECTION SYSTEM
    2.
    发明申请
    FLUORESCENCE DETECTION SYSTEM 审中-公开

    公开(公告)号：WO2023069651A1

    公开(公告)日：2023-04-27

    申请号：PCT/US2022/047322

    申请日：2022-10-20

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： THRUSH, Evan ,  SWIHART, Stephen L. ,  HEFNER, Eli A. ,  GRIFFIN, Michael ,  LU, Li

    IPC: G01N21/64 ,  C12Q1/686 ,  G01N21/25 ,  G02B21/06

    Abstract: A fluorescence detection system, including apparatus and methods, suitable for qPCR and other fluorescence-based analyses. The system may comprise various components, including a stage, an illumination module, a detection module, and an optical relay structure. The stage may be configured to support a sample holder. The illumination module may include one or more discrete light sources configured to produce excitation light. The detection module may be configured to detect fluorescence emission light produced, in response to the excitation light, by a fluorescent sample positioned in the sample holder. The optical relay structure may include a beamsplitter assembly configured to direct the excitation light from the illumination module along an illumination path to the sample holder and to direct the fluorescence emission light from the sample holder along a response path to the imaging module. The system may enhance the quality of excitation light hitting samples in the sample holder, for example, by collimating and/or homogenizing the light.

Patent Agency Ranking