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公开(公告)号：WO2008109878A3
公开(公告)日：2009-01-08
申请号：PCT/US2008056331
申请日：2008-03-07
Applicant: CALIFORNIA INST OF TECHN , MALTEZOS GEORGE , SCHERER AXEL , HUANG JINGQUING , DICKINSON ALEX , JOHNSTON MATTHEW
Inventor： MALTEZOS GEORGE , SCHERER AXEL , HUANG JINGQUING , DICKINSON ALEX , JOHNSTON MATTHEW
IPC: C12M1/00
CPC classification number: B01L3/502 , B01L7/52 , B01L2200/143 , B01L2200/16 , B01L2300/021 , B01L2300/024 , B01L2300/0809 , B01L2300/0838 , B01L2300/0867 , B01L2400/0478 , B01L2400/0487 , B01L2400/0644 , G06Q99/00
Abstract: The invention provides, in different aspects, a system, sample preparation device, sample processing cartridge, kit, methods of use, business methods, and computer program product.
Abstract translation: 本发明在不同方面提供了系统，样品制备装置，样品处理盒，试剂盒，使用方法，商业方法和计算机程序产品。
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公开(公告)号：WO2008070198A8
公开(公告)日：2008-12-24
申请号：PCT/US2007069197
申请日：2007-05-17
Applicant: CALIFORNIA INST OF TECHN , MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
Inventor： MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
CPC classification number: G01N21/645 , B01L3/508 , B01L7/02 , B01L7/52 , B01L7/525 , B01L2300/0809 , B01L2300/0832 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185
Abstract: This invention provides a system for performing PCR, and real time PCR in particular, with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block.
Abstract translation: 本发明提供了一种用于进行PCR的系统，特别是用于实时PCR的系统，具有很高的速度和特异性。 该系统采用含有液体组合物的加热块来快速地将热量传递至反应容器和从反应容器传递热量 该系统利用液态金属的反射特性将来自PCR的信号反射到容器中并从顶部反射。 通过这种方式，可以通过光学组件实时测量信号，而无需从加热块中取出容器。
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公开(公告)号：WO2008070198A3
公开(公告)日：2009-04-16
申请号：PCT/US2007069197
申请日：2007-05-17
Applicant: CALIFORNIA INST OF TECHN , MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
Inventor： MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
CPC classification number: G01N21/645 , B01L3/508 , B01L7/02 , B01L7/52 , B01L7/525 , B01L2300/0809 , B01L2300/0832 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185
Abstract: This invention provides a system for performing PCR, and real time PCR in particular, with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block.
Abstract translation: 本发明提供了一种用于特别快速和特异性地进行PCR和实时PCR的系统。 该系统采用含有液体组合物的热块来快速地将热量传递到反应容器和从其返回。 该系统利用液态金属的反射特性，将来自PCR的信号反射到容器中并排出顶部。 以这种方式，可以通过光学组件实时地测量信号，而不从容器中取出容器。
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公开(公告)号：EP2027251A4
公开(公告)日：2010-05-05
申请号：EP07783905
申请日：2007-05-17
Applicant: CALIFORNIA INST OF TECHN
Inventor： MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
CPC classification number: G01N21/645 , B01L3/508 , B01L7/02 , B01L7/52 , B01L7/525 , B01L2300/0809 , B01L2300/0832 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185
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