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Patent Agency Ranking
公开(公告)号：WO2008070198A3
公开(公告)日：2009-04-16
申请号：PCT/US2007069197
申请日：2007-05-17
Applicant: CALIFORNIA INST OF TECHN , MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
Inventor： MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
CPC classification number: G01N21/645 , B01L3/508 , B01L7/02 , B01L7/52 , B01L7/525 , B01L2300/0809 , B01L2300/0832 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185
Abstract: This invention provides a system for performing PCR, and real time PCR in particular, with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block.
Abstract translation: 本发明提供了一种用于特别快速和特异性地进行PCR和实时PCR的系统。 该系统采用含有液体组合物的热块来快速地将热量传递到反应容器和从其返回。 该系统利用液态金属的反射特性，将来自PCR的信号反射到容器中并排出顶部。 以这种方式，可以通过光学组件实时地测量信号，而不从容器中取出容器。
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2.发明公开
公开(公告)号：EP2689005A4
公开(公告)日：2014-09-03
申请号：EP12760549
申请日：2012-03-19
Applicant: CALIFORNIA INST OF TECHN
Inventor： WALKER CHRISTOPHER I , RAJAGOPAL ADITYA
CPC classification number: B01L3/502707 , B01L7/52 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/1827
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公开(公告)号：EP2027251A4
公开(公告)日：2010-05-05
申请号：EP07783905
申请日：2007-05-17
Applicant: CALIFORNIA INST OF TECHN
Inventor： MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
CPC classification number: G01N21/645 , B01L3/508 , B01L7/02 , B01L7/52 , B01L7/525 , B01L2300/0809 , B01L2300/0832 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185
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4.发明申请
公开(公告)号：WO2012129157A3
公开(公告)日：2012-12-27
申请号：PCT/US2012029631
申请日：2012-03-19
Applicant: CALIFORNIA INST OF TECHN , WALKER CHRISTOPHER I , RAJAGOPAL ADITYA
Inventor： WALKER CHRISTOPHER I , RAJAGOPAL ADITYA
CPC classification number: B01L3/502707 , B01L7/52 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/1827
Abstract: A printed circuit structure containing a fluidic chamber configured to receive an aqueous solution containing a sample to be analyzed and fluorophore for polymerase chain reaction analysis. The printed circuit structure also contains a heating element that provides for temperature cycling of the fluidic chamber to support polymerase chain reaction analysis.
Abstract translation: 一种包含流化室的印刷电路结构，其配置为接收含有待分析样品的水溶液和用于聚合酶链式反应分析的荧光团。 印刷电路结构还包含加热元件，其提供流体室的温度循环以支持聚合酶链式反应分析。
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公开(公告)号：WO2008070198A8
公开(公告)日：2008-12-24
申请号：PCT/US2007069197
申请日：2007-05-17
Applicant: CALIFORNIA INST OF TECHN , MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
Inventor： MALTEZOS GEORGE , JOHNSTON MATTHEW , GOODWIN DAVID , SCHERER AXEL , WALKER CHRISTOPHER I
CPC classification number: G01N21/645 , B01L3/508 , B01L7/02 , B01L7/52 , B01L7/525 , B01L2300/0809 , B01L2300/0832 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185
Abstract: This invention provides a system for performing PCR, and real time PCR in particular, with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block.
Abstract translation: 本发明提供了一种用于进行PCR的系统，特别是用于实时PCR的系统，具有很高的速度和特异性。 该系统采用含有液体组合物的加热块来快速地将热量传递至反应容器和从反应容器传递热量 该系统利用液态金属的反射特性将来自PCR的信号反射到容器中并从顶部反射。 通过这种方式，可以通过光学组件实时测量信号，而无需从加热块中取出容器。
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