公开(公告)号：WO2019209377A3

公开(公告)日：2019-10-31

申请号：PCT/US2018/063486

申请日：2018-11-30

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： ADALIAN, Dvin ,  CHEN, Samson ,  JILANI, Muhammad M. ,  SCHERER, Axel ,  MADERO, Xiomara Linnette ,  SMITH, Richard

IPC: G01N27/327 ,  G01N27/416

Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.

公开(公告)号：WO2019209377A2

公开(公告)日：2019-10-31

申请号：PCT/US2018/063486

申请日：2018-11-30

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： ADALIAN, Dvin ,  CHEN, Samson ,  JILANI, Muhammad M. ,  SCHERER, Axel ,  MADERO, Xiomara Linnette ,  SMITH, Richard

IPC: G01N27/327

Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.

公开(公告)号：EP4235165A3

公开(公告)日：2023-09-27

申请号：EP23162484.2

申请日：2018-11-30

Applicant: California Institute of Technology

Inventor： ADALIAN, Dvin ,  CHEN, Samson ,  JILANI, Muhammad M. ,  SCHERER, Axel ,  MADERO, Xiomara Linnette ,  SMITH, Richard

IPC: G01N27/327 ,  G01N27/416 ,  A61B5/145 ,  A61B5/1486

Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.

公开(公告)号：EP4235165A2

公开(公告)日：2023-08-30

申请号：EP23162484.2

申请日：2018-11-30

Applicant: California Institute of Technology

Inventor： ADALIAN, Dvin ,  CHEN, Samson ,  JILANI, Muhammad M. ,  SCHERER, Axel ,  MADERO, Xiomara Linnette ,  SMITH, Richard

IPC: G01N27/327 ,  G01N27/416 ,  A61B5/145 ,  A61B5/1486

Abstract: Measurement of target analytes is carried out with an enzyme-based sensor. The enzyme hydrogel is protected by a porous layer of a metallic material. The size of the pores is small enough to prevent degradation of the enzyme layer caused by the immune system of an organism, but large enough to allow transfer of molecules that participate in the electrochemical reaction allowing the enzyme to detect the target analytes.

公开(公告)号：EP3775861A2

公开(公告)日：2021-02-17

申请号：EP18916848.7

申请日：2018-11-30

Applicant: California Institute of Technology

Inventor： ADALIAN, Dvin ,  CHEN, Samson ,  JILANI, Muhammad M. ,  SCHERER, Axel ,  MADERO, Xiomara Linnette ,  SMITH, Richard

IPC: G01N27/327 ,  G01N27/416