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公开(公告)号:US20180318443A1
公开(公告)日:2018-11-08
申请号:US15832526
申请日:2017-12-05
Applicant: Case Western Reserve University
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
CPC classification number: A61K47/6911 , A61K38/49 , A61K47/62 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0084 , C12Y304/21068
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle or microparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle or microparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
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公开(公告)号:US11648323B2
公开(公告)日:2023-05-16
申请号:US16933434
申请日:2020-07-20
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
CPC classification number: A61K47/6911 , A61K38/49 , A61K47/62 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0084 , C12Y304/21068
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle or microparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle or microparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
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公开(公告)号:US10716865B2
公开(公告)日:2020-07-21
申请号:US15832526
申请日:2017-12-05
Applicant: Case Western Reserve University
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle or microparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle or microparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
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公开(公告)号:US09107963B2
公开(公告)日:2015-08-18
申请号:US13863005
申请日:2013-04-15
Applicant: Case Western Reserve University
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
IPC: A61K38/00 , A61K38/36 , C07K14/745 , A61K9/127 , A61K9/16 , A61K9/50 , A61K38/04 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , A61K47/48 , A61K38/49 , A61K49/00
CPC classification number: A61K47/48815 , A61K38/49 , A61K47/62 , A61K47/6911 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0084
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
Abstract translation: 用于诊断和治疗应用的组合物包括具有外表面和与纳米颗粒表面缀合的多个靶向部分的异源纳米颗粒,靶向部分包括第一活化的血小板靶向部分和第二活化的血小板靶向部分。
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公开(公告)号:US20210170047A1
公开(公告)日:2021-06-10
申请号:US16933434
申请日:2020-07-20
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle or microparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle or microparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
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公开(公告)号:US09833518B2
公开(公告)日:2017-12-05
申请号:US14827785
申请日:2015-08-17
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
CPC classification number: A61K47/6911 , A61K38/49 , A61K47/62 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0084 , C12Y304/21068
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle or microparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle or microparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
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公开(公告)号:US20160015833A1
公开(公告)日:2016-01-21
申请号:US14827785
申请日:2015-08-17
Applicant: Case Western Reserve University
Inventor: ANIRBAN SEN GUPTA , Madhumitha Ravikumar , Christa Modery
CPC classification number: A61K47/6911 , A61K38/49 , A61K47/62 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0084 , C12Y304/21068
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle or microparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle or microparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
Abstract translation: 用于诊断和治疗应用的组合物包括具有外表面和与纳米颗粒或微粒表面缀合的多个靶向部分的异源纳米颗粒或微粒,靶向部分包括第一活化的血小板靶向部分和第二活化血小板 靶向部分。
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公开(公告)号:US20140023591A1
公开(公告)日:2014-01-23
申请号:US13863005
申请日:2013-04-15
Applicant: Case Western Reserve University
Inventor: Anirban Sen Gupta , Madhumitha Ravikumar , Christa Modery
CPC classification number: A61K47/48815 , A61K38/49 , A61K47/62 , A61K47/6911 , A61K49/0032 , A61K49/0041 , A61K49/0043 , A61K49/0084
Abstract: A composition for use in diagnostic and therapeutic applications includes a heteromultivalent nanoparticle having an outer surface and a plurality of targeting moieties conjugated to the surface of the nanoparticle, the targeting moieties includes a first activated platelet targeting moiety and a second activated platelet targeting moiety.
Abstract translation: 用于诊断和治疗应用的组合物包括具有外表面和与纳米颗粒表面缀合的多个靶向部分的异源纳米颗粒,靶向部分包括第一活化的血小板靶向部分和第二活化的血小板靶向部分。
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