公开(公告)号：CA2540881A1

公开(公告)日：2005-05-12

申请号：CA2540881

申请日：2004-10-22

Applicant: CELLTECH R&D LTD

Inventor： HUTCHINGS MARTIN CLIVE ,  LAING VICTORIA ELIZABETH ,  TREVITT GRAHAM PETER ,  ALEXANDER RIKKI PETER ,  DAVIS JEREMY MARTIN

IPC: C07D495/04 ,  A61K31/4365 ,  A61P29/00 ,  A61P37/00 ,  C07D221/00 ,  C07D333/00

Abstract: A series of thieno[2,3-b]pyridin-6(7H)-one derivatives, substituted in the 3-position by an arylcarbonyl or heteroaryl-carbonyl moiety, being inhibitors of p38 MAP kinase, are accordingly of use in medicine, for example in the treatment and/or prevention of immune or inflammatory disorders.