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    ALBUMIN-BINDING COMPOUNDS
    2.
    发明申请
    ALBUMIN-BINDING COMPOUNDS 审中-公开
    铝结合化合物

    公开(公告)号：WO2005117984A2

    公开(公告)日：2005-12-15

    申请号：PCT/GB2005002084

    申请日：2005-05-25

    Applicant: CELLTECH R&D LTD ,  EATON MICHAEL ANTHONY WILLIAM ,  NORMAN TIMOTHY JOHN ,  PORTER JOHN ROBERT

    Inventor： EATON MICHAEL ANTHONY WILLIAM ,  NORMAN TIMOTHY JOHN ,  PORTER JOHN ROBERT

    IPC: A61K47/48

    CPC classification number: A61K47/542 ,  A61K47/60

    Abstract: The present invention provides an albumin-binding compound essentially of the following elements: a spacer group, a water-soluble bridging group, a fatty acid chain and an acidic group characterised in that the acidic group is attached to the distal end of the fatty acid chain. The invention also provides an albumin-binding compound to which one or more biologically active moieties are attached.

    Abstract translation: 本发明提供了基本上具有以下元素的白蛋白结合化合物：间隔基，水溶性桥连基团，脂肪酸链和酸性基团，其特征在于酸性基团连接到脂肪酸的末端 链。 本发明还提供了与一个或多个生物活性部分连接的白蛋白结合化合物。

    BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TO ANTIBODIES
    3.
    发明申请
    BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TO ANTIBODIES 审中-公开
    用于将聚合物残留物连接到抗体的分支聚乙烯甘油

    公开(公告)号：WO2005061005A3

    公开(公告)日：2005-11-03

    申请号：PCT/GB2004005246

    申请日：2004-12-14

    Applicant: CELLTECH R&D LTD ,  NORMAN TIMOTHY JOHN

    Inventor： NORMAN TIMOTHY JOHN

    IPC: A61K47/48

    CPC classification number: A61K47/60

    Abstract: Branched molecular scaffolds are provided which are capable of linking two polymer residues (derived, for example, from polyethylene glycol) to two, three or four residues derived from biologically active molecules (e.g. from whole antibodies or from functionally active fragments or derivatives thereof), the latter being attached to the scaffold by means of hydrolytically stable linkages.

    Abstract translation: 提供支链分子支架，其能够将两个聚合物残基（衍生自例如聚乙二醇）与衍生自生物活性分子（例如来自全部抗体或其功能活性片段或衍生物）的两个，三个或四个残基连接， 后者通过水解稳定的键连接到支架上。

    Branched polyethylene glycol for linking polymer residues to antibodies
    6.
    发明专利
    Branched polyethylene glycol for linking polymer residues to antibodies 未知

    公开(公告)号：AU2004305291A1

    公开(公告)日：2005-07-07

    申请号：AU2004305291

    申请日：2004-12-14

    Applicant: CELLTECH R&D LTD

    Inventor： NORMAN TIMOTHY JOHN

    IPC: A61K47/48

    Abstract: Branched molecular scaffolds are provided which are capable of linking two polymer residues (derived, for example, from polyethylene glycol) to two, three or four residues derived from biologically active molecules (e.g. from whole antibodies or from functionally active fragments or derivatives thereof), the latter being attached to the scaffold by means of hydrolytically stable linkages.

    BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TOANTIBODIES
    8.
    发明专利
    BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TOANTIBODIES 未知

    公开(公告)号：CA2545805A1

    公开(公告)日：2005-07-07

    申请号：CA2545805

    申请日：2004-12-14

    Applicant: CELLTECH R&D LTD

    Inventor： NORMAN TIMOTHY JOHN

    IPC: A61K47/48

    Abstract: Branched molecular scaffolds are provided which are capable of linking two polymer residues (derived, for example, from polyethylene glycol) to two, three or four residues derived from biologically active molecules (e.g. from whole antibodies or from functionally active fragments or derivatives thereof), the latter being attached to the scaffold by means of hydrolytically stable linkages.

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