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公开(公告)号:HRP940090B1
公开(公告)日:1996-04-30
申请号:HRP940090
申请日:1994-02-11
Applicant: CIBA GEIGY AG
Inventor: GALLAY JEAN JACQUES , KUEHNE MANFRED , MEYER ALFRED , SCHELLENBAUM MAX , RECHSTEINER OSWALD
IPC: A61K31/415 , C07D235/28
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公开(公告)号:AU622640B2
公开(公告)日:1992-04-16
申请号:AU3114989
申请日:1989-03-08
Applicant: CIBA GEIGY AG
Inventor: ZONDLER HELMUT , MEYER ALFRED , ECKHARDT WOLFGANG , KUNZ WALTER
IPC: A01N43/40 , A01N43/50 , A01N43/54 , A01N43/58 , A01N43/60 , A01N43/653 , C07D213/81 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , A01N43/56 , A01N43/84
Abstract: Novel substituted isonicotinic acid amides of the general formula in which X in ortho/ortho'-position are equal and represent fluorine, chlorine, bromine or iodine; Q1 is unsubstituted pyridimin-4-yl, or pyrimidin-4-yl substituted by R1, R2 and R3; Q2 is unsubstituted pyrimidin-2-yl, or pyrimidin-2-yl substituted by R1, R2 and R3; Q3 is unsubstituted pyrimidin-5-yl, or pyrimidin-5-yl substituted by R1, R2 and R3; Q4 is pyridin-2-yl, pyridin-3-yl or pyridin-4-yl each of which is unsubstituted or substituted by R1, R2 and R3; Q5 is pyridazin-3-yl or pyridazin-4-yl each of which is unsubstituted or substituted by R1, R2 and R3; Q6 is unsubstituted pyrazin-2-yl, or pyrazin-2-yl substituted by R1, R2 and R3; R1, R2, R3 are hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl having from 1 to 3 halogen atoms, C1-C6alkoxy, C2-C6alkoxyalkyl, C1-C6thioalkyl, C1-C6haloalkoxy having from 1 to 5 halogen atoms, C3-C6alkenyloxy, C3-C6alkynyloxy, C3-C6thioalkenyl, C3-C6cycloalkyl, C3-C6cycloalkyl substituted by methyl, or nitro, cyano, the radical CH(OR4)2 or COOR4 in which R4 is C1-C4alkyl; also phenyl, phenoxy, thiophenyl, benzyl, benzyloxy or thiobenzyl; or phenyl, phenoxy, thiophenyl, benzyl, benzyloxy or thiobenzyl each substituted at least once by C1-C3alkyl, C1-C3-alkoxy, C1-C3haloalkyl having from 1 to 3 halogen atoms, halogen, nitro or by cyano; and also N(R5)R6 in which R5 and R6, independently of one another, are each C1-C6alkyl; and furthermore piperidinyl, pyrrolidinyl, morpholinyl, imidazolyl or triazolyl, or piperidinyl, pyrrolidinyl, morpholinyl, imidazolyl or triazolyl each substituted by C1-C3alkyl, C1-C3alkoxy, C1-C3haloalkyl having from 1 to 3 halogen atoms, halogen, nitro or by cyano. The novel active ingredients have plant-protecting properties and are suitable especially for the preventive protection of plants against attack by phytopathogenic microorganisms such as fungi, bacteria and viruses.
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公开(公告)号:DK161199C
公开(公告)日:1991-11-25
申请号:DK573883
申请日:1983-12-13
Applicant: CIBA GEIGY AG
Inventor: STURM ELMAR , MEYER ALFRED
IPC: A01N43/50 , A01N43/653 , A01P3/00 , C07C39/00 , C07C45/63 , C07C45/71 , C07D233/60 , C07D233/64 , C07D249/08 , C07D303/08 , C07D303/22 , C07D303/34 , C07D521/00
Abstract: 1-Azolyl-2-aryl-3-fluoro-alkan-2- ols of the general formula I in which Az is 1H-1,2,4-triazole, 4H-1,2,4-triazole or 1H-imidazole; Ar is an unsubstituted or substituted aromatic radical from the series comprising phenyl, biphenyl, phenoxyphenyl and naphthyl; R1 is hydrogen, C1-C4-alkyl, C3-C5-alkenyl or benzyl; R2 is hydrogen, fluorine or C1-C6-alkyl and R3 is hydrogen, fluorine, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-alkylthio, phenyl, phenoxy, phenylthio or C3-C7-cycloalkyl, and each aromatic substituent or aromatic moiety of a substituent is unsubstituted or mono- or poly-substituted by halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkyl, nitro and/or cyano; including the acid addition salts, quaternary azolium salts and metal complexes, are useful for controlling phytopathogenic microorganisms.
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公开(公告)号:ZA8902094B
公开(公告)日:1989-11-29
申请号:ZA8902094
申请日:1989-03-20
Applicant: CIBA GEIGY AG
Inventor: ECKHARDT WOLFGANG , WOLFGANG ECKHARDT , MEYER ALFRED , ALFRED MEYER , KUNZ WALTER , WALTER KUNZ
IPC: A01N43/56 , A01N43/653 , A01N43/74 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01N43/824 , A01N43/836 , A01N43/88 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D , A01N
CPC classification number: C07D401/12 , A01N43/56 , A01N43/653 , A01N43/74 , A01N43/80 , A01N43/82 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
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公开(公告)号:BR8901086A
公开(公告)日:1989-10-31
申请号:BR8901086
申请日:1989-03-08
Applicant: CIBA GEIGY AG
Inventor: ZONDLER HELMUT , MEYER ALFRED , ECKHARDT WOLFGANG , KUNZ WALTER
IPC: A01N43/40 , A01N43/50 , A01N43/54 , A01N43/58 , A01N43/60 , A01N43/653 , C07D213/81 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D411/14 , A01N43/48 , A01N43/72
Abstract: Novel substituted isonicotinic acid amides of the general formula in which X in ortho/ortho'-position are equal and represent fluorine, chlorine, bromine or iodine; Q1 is unsubstituted pyridimin-4-yl, or pyrimidin-4-yl substituted by R1, R2 and R3; Q2 is unsubstituted pyrimidin-2-yl, or pyrimidin-2-yl substituted by R1, R2 and R3; Q3 is unsubstituted pyrimidin-5-yl, or pyrimidin-5-yl substituted by R1, R2 and R3; Q4 is pyridin-2-yl, pyridin-3-yl or pyridin-4-yl each of which is unsubstituted or substituted by R1, R2 and R3; Q5 is pyridazin-3-yl or pyridazin-4-yl each of which is unsubstituted or substituted by R1, R2 and R3; Q6 is unsubstituted pyrazin-2-yl, or pyrazin-2-yl substituted by R1, R2 and R3; R1, R2, R3 are hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl having from 1 to 3 halogen atoms, C1-C6alkoxy, C2-C6alkoxyalkyl, C1-C6thioalkyl, C1-C6haloalkoxy having from 1 to 5 halogen atoms, C3-C6alkenyloxy, C3-C6alkynyloxy, C3-C6thioalkenyl, C3-C6cycloalkyl, C3-C6cycloalkyl substituted by methyl, or nitro, cyano, the radical CH(OR4)2 or COOR4 in which R4 is C1-C4alkyl; also phenyl, phenoxy, thiophenyl, benzyl, benzyloxy or thiobenzyl; or phenyl, phenoxy, thiophenyl, benzyl, benzyloxy or thiobenzyl each substituted at least once by C1-C3alkyl, C1-C3-alkoxy, C1-C3haloalkyl having from 1 to 3 halogen atoms, halogen, nitro or by cyano; and also N(R5)R6 in which R5 and R6, independently of one another, are each C1-C6alkyl; and furthermore piperidinyl, pyrrolidinyl, morpholinyl, imidazolyl or triazolyl, or piperidinyl, pyrrolidinyl, morpholinyl, imidazolyl or triazolyl each substituted by C1-C3alkyl, C1-C3alkoxy, C1-C3haloalkyl having from 1 to 3 halogen atoms, halogen, nitro or by cyano. The novel active ingredients have plant-protecting properties and are suitable especially for the preventive protection of plants against attack by phytopathogenic microorganisms such as fungi, bacteria and viruses.
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公开(公告)号:PH23605A
公开(公告)日:1989-09-11
申请号:PH34617
申请日:1986-12-18
Applicant: CIBA GEIGY AG
Inventor: FRICK WILLY , MEYER ALFRED , NYFELER ROBERT
IPC: A01N43/50 , A01N43/653 , C07D249/08 , C07D521/00 , C07D233/60
Abstract: Novel compounds of the formula in which R1 is hydrogen, halogen, C1-C2-alkyl or CF3, R2 is halogen or C1-C2-alkyl, R3 is C1-C5-alkyl or C3-C5-alkenyl, R4 is hydrogen, C1-C4-alkyl, C3-C4-alkenyl or the group where R5, R6 and R7 independently of one another are hydrogen, nitro, halogen, cyano, C1-C3-alkyl, C1-C3-alkoxy, C1-C3-haloalkoxy or CF3 and Y is a nitrogen atom or the CH group, including the acid addition salts, quaternary azolium salts and metal salt complexes thereof which have microbicidal properties. The novel active substances can be employed in crop protection for preventing crop plants from being attacked by phytopathogenic microorganisms and for controlling harmful microorganisms.
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公开(公告)号:NO161256C
公开(公告)日:1989-07-26
申请号:NO834592
申请日:1983-12-13
Applicant: CIBA GEIGY AG
Inventor: STURM ELMAR , MEYER ALFRED
IPC: A01N43/50 , A01N43/653 , A01P3/00 , C07C39/00 , C07C45/63 , C07C45/71 , C07D233/60 , C07D233/64 , C07D249/08 , C07D303/08 , C07D303/22 , C07D303/34 , C07D521/00
Abstract: 1-Azolyl-2-aryl-3-fluoro-alkan-2- ols of the general formula I in which Az is 1H-1,2,4-triazole, 4H-1,2,4-triazole or 1H-imidazole; Ar is an unsubstituted or substituted aromatic radical from the series comprising phenyl, biphenyl, phenoxyphenyl and naphthyl; R1 is hydrogen, C1-C4-alkyl, C3-C5-alkenyl or benzyl; R2 is hydrogen, fluorine or C1-C6-alkyl and R3 is hydrogen, fluorine, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-alkylthio, phenyl, phenoxy, phenylthio or C3-C7-cycloalkyl, and each aromatic substituent or aromatic moiety of a substituent is unsubstituted or mono- or poly-substituted by halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkyl, nitro and/or cyano; including the acid addition salts, quaternary azolium salts and metal complexes, are useful for controlling phytopathogenic microorganisms.
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公开(公告)号:PH23094A
公开(公告)日:1989-04-10
申请号:PH31609
申请日:1984-12-19
Applicant: CIBA GEIGY AG
Inventor: FRICK WILLY , MEYER ALFRED , NYFELER ROBERT
IPC: A01N43/50 , A01N43/653 , C07C45/63 , C07D249/08 , C07C49/80 , C07D233/56 , C07D233/60 , C07D249/00 , C07D307/00 , C07D405/12 , C07D521/00
Abstract: The invention relates to 1-aryl-2-fluoro-2-azolyl alkanones, alkanols, esters and ethers of formula I (I) wherein Az is 1H-1,2,4-triazole, 4H-1,2,4-triazole or 1H-imidazole; T is -C(O)-, -CH(OH)- or one of the groups wherein R7 is C1-C6alkyl which is unsubstituted or substituted by C1-C3-alkoxy, halogen or cyano, or is C3-C6alkenyl, C3-C6alkynyl, C3-C6cycloalkyl, 2-furyl, 2-tetrahydrofuryl, or is phenyl or benzyl, each unsubstituted or substituted by halogen, nitro, C1-C3-alkyl, C1-C3alkoxy, C1-C3haloalkyl and/or C1-C3haloalkoxy; R8, R9 and R10 are each independently hydrogen, nitro, halogen, cyano, C1-C3alkyl, C1-C3alkoxy, C1-C3haloalkoxy, -COO(C1-C3alkyl), NH2 or NHCOCH3; R is hydrogen or C1-C6alkyl; R1 and R2 are each independently hydrogen, halogen, C1-C6alkyl, C1-C6-alkoxy, C1-C6haloalkyl, C1-C6haloalkoxy, nitro and/or cyano; and R3 is hydrogen, halogen, C1-C6alkyl, C1-C6alkoxy, C1-C6haloalkyl, C1-C6 haloalkoxy, nitro, cyano and/or the group wherein X is O, S, SO or SO2; R4, R5 and R6 are each independently hydrogen, halogen, cyano, nitro, C1-C6alkyl, C1-C6alkoxy, C1-C6haloalkyl and/or C1-C6haloalkoxy; and to the acid addition salts and metal complexes thereof. These compounds have microbicidal properties and can be used in particular against diseases occurring in rice. The invention also relates to the preparation and use of these compounds.
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公开(公告)号:HU196891B
公开(公告)日:1989-02-28
申请号:HU424683
申请日:1983-12-13
Applicant: CIBA GEIGY AG
Inventor: STURM ELMAR , MEYER ALFRED
IPC: A01N43/50 , A01N43/653 , A01P3/00 , C07C39/00 , C07C45/63 , C07C45/71 , C07D233/60 , C07D233/64 , C07D249/08 , C07D303/08 , C07D303/22 , C07D303/34 , C07D521/00
Abstract: 1-Azolyl-2-aryl-3-fluoro-alkan-2- ols of the general formula I in which Az is 1H-1,2,4-triazole, 4H-1,2,4-triazole or 1H-imidazole; Ar is an unsubstituted or substituted aromatic radical from the series comprising phenyl, biphenyl, phenoxyphenyl and naphthyl; R1 is hydrogen, C1-C4-alkyl, C3-C5-alkenyl or benzyl; R2 is hydrogen, fluorine or C1-C6-alkyl and R3 is hydrogen, fluorine, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-alkylthio, phenyl, phenoxy, phenylthio or C3-C7-cycloalkyl, and each aromatic substituent or aromatic moiety of a substituent is unsubstituted or mono- or poly-substituted by halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-haloalkyl, nitro and/or cyano; including the acid addition salts, quaternary azolium salts and metal complexes, are useful for controlling phytopathogenic microorganisms.
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公开(公告)号:AU579338B2
公开(公告)日:1988-11-24
申请号:AU3695784
申请日:1984-12-19
Applicant: CIBA GEIGY AG
Inventor: FRICK WILLY , MEYER ALFRED , NYFELER ROBERT
IPC: C07D249/08 , A01N43/50 , A01N43/653 , C07C45/63 , C07C49/80 , C07D233/56 , C07D233/60 , C07D249/00 , C07D307/00 , C07D405/12 , C07D521/00 , A01N43/64
Abstract: The invention relates to 1-aryl-2-fluoro-2-azolyl alkanones, alkanols, esters and ethers of formula I (I) wherein Az is 1H-1,2,4-triazole, 4H-1,2,4-triazole or 1H-imidazole; T is -C(O)-, -CH(OH)- or one of the groups wherein R7 is C1-C6alkyl which is unsubstituted or substituted by C1-C3-alkoxy, halogen or cyano, or is C3-C6alkenyl, C3-C6alkynyl, C3-C6cycloalkyl, 2-furyl, 2-tetrahydrofuryl, or is phenyl or benzyl, each unsubstituted or substituted by halogen, nitro, C1-C3-alkyl, C1-C3alkoxy, C1-C3haloalkyl and/or C1-C3haloalkoxy; R8, R9 and R10 are each independently hydrogen, nitro, halogen, cyano, C1-C3alkyl, C1-C3alkoxy, C1-C3haloalkoxy, -COO(C1-C3alkyl), NH2 or NHCOCH3; R is hydrogen or C1-C6alkyl; R1 and R2 are each independently hydrogen, halogen, C1-C6alkyl, C1-C6-alkoxy, C1-C6haloalkyl, C1-C6haloalkoxy, nitro and/or cyano; and R3 is hydrogen, halogen, C1-C6alkyl, C1-C6alkoxy, C1-C6haloalkyl, C1-C6 haloalkoxy, nitro, cyano and/or the group wherein X is O, S, SO or SO2; R4, R5 and R6 are each independently hydrogen, halogen, cyano, nitro, C1-C6alkyl, C1-C6alkoxy, C1-C6haloalkyl and/or C1-C6haloalkoxy; and to the acid addition salts and metal complexes thereof. These compounds have microbicidal properties and can be used in particular against diseases occurring in rice. The invention also relates to the preparation and use of these compounds.
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