PROCESS FOR THE PREPARATION OF 1H-AZOLE DERIVATIVES

    公开(公告)号:CA1154773A

    公开(公告)日:1983-10-04

    申请号:CA367087

    申请日:1980-12-18

    Applicant: CIBA GEIGY AG

    Abstract: An improved process for the preparation of 2-tert.-butyl-2-(1-phenoxy-1-(1H-azol-1-yl)!-methyl-ketales of the formula wherein X represents -CH= or -N=; R1, R2 and R3 are each independently selected from the group consisting of hydrogen, halogen, lower alkyl, cyano, methoxy, phenyl and nitro; A represents -CH(R4)-CH(R5)- or -CH2-C(R6)(R7)-CH2-; R4 and R5 are each independently selected from the group consisting of hydrogen, C12-C6-alkyl, C1-C6-alkoxymethyl and phenoxymethyl or said substituents R4 and R5 form together a tetramethylene group; and R6 and R7 are each independently selected from the group consisting of hydrogen and lower alkyl, which process comprises reacting a 2-tert.-butyl-2-¢1-phenoxy-1-halo!-methyl-ketale with a quaternary ammonium or phosphonium salt of an azole. The azoles used are 1H-1,2,4-triazole or 1H-imidazole.

Patent Agency Ranking