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公开(公告)号：WO1997016160A1
公开(公告)日：1997-05-09
申请号：PCT/US1996017364
申请日：1996-10-29
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： COLGATE-PALMOLIVE COMPANY , BLAKE-HASKINS, John, C. , COLLIGAN, Mary, L. , MANDANAS, Benjamin, Y. , GAFFAR, Abdul
IPC: A61K07/16
CPC classification number: A61Q11/00 , A61K8/21 , A61K8/73 , A61K2800/88
Abstract: A method is disclosed for fluoridating teeth using a two-component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof are the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and the second dentifrice compounds are maintained separate from the other until mixed for application to teeth.
Abstract translation: 公开了一种使用双组分洁牙剂系统对牙齿进行氟化的方法，其中第一组分是含水载色剂中含有氟离子可释放的可水解复合氟化物如氟硅酸钠的稳定的半固体可挤出洁齿剂组合物，其中黄原胶 胶是主要的增稠剂，甘油，山梨糖醇或其混合物是保湿剂，第二组分是含有钙离子可释放化合物的半固体可挤出洁牙剂组合物和含有黄原胶作为主要增稠剂的水性载体中的研磨剂 和甘油，山梨糖醇或其混合物作为保湿剂。 第一和第二洁牙剂化合物与另一种洁牙剂化合物保持分开，直到混合以施用于牙齿。
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公开(公告)号：EP0858316A1
公开(公告)日：1998-08-19
申请号：EP96937076.0
申请日：1996-10-29
Applicant: Colgate-Palmolive Company
Inventor： BLAKE-HASKINS, John, C. , COLLIGAN, Mary, L. , MANDANAS, Benjamin, Y. , GAFFAR, Abdul
CPC classification number: A61Q11/00 , A61K8/21 , A61K8/73 , A61K2800/88
Abstract: A method is disclosed for fluoridating teeth using a two-component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof are the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and the second dentifrice compounds are maintained separate from the other until mixed for application to teeth.
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公开(公告)号：EP0858316B1
公开(公告)日：2001-12-19
申请号：EP96937076.6
申请日：1996-10-29
Applicant: Colgate-Palmolive Company
Inventor： BLAKE-HASKINS, John, C. , COLLIGAN, Mary, L. , MANDANAS, Benjamin, Y. , GAFFAR, Abdul
CPC classification number: A61Q11/00 , A61K8/21 , A61K8/73 , A61K2800/88
Abstract: A method is disclosed for fluoridating teeth using a two-component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof are the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and the second dentifrice compounds are maintained separate from the other until mixed for application to teeth.
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公开(公告)号：EP0973491A1
公开(公告)日：2000-01-26
申请号：EP98913415.0
申请日：1998-04-07
Applicant: Colgate-Palmolive Company
Inventor： BLAKE-HASKINS, John, C. , COLLIGAN, Mary, L. , COLLINS, Michael, A. , MANDANAS, Benjamin, Y. , GAFFAR, Abdul
CPC classification number: A61Q11/00 , A61K8/21 , A61K8/25 , A61K2800/88
Abstract: A composition and method is disclosed for fluoridating teeth using a two component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which a carrageenan gum having major kappa and lambda forms as the primary thickening agent and the abrasive is a silica providing an acid pH when slurried with water, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and the abrasive and carrageenan gum in an aqueous vehicle. The first and second dentifrice compounds are maintained separate from the other until mixed for application to teeth.
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