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    DUAL COMPONENT DENTIFRICE COMPOSITION FOR FLUORIDATING TEETH
    2.
    发明申请
    DUAL COMPONENT DENTIFRICE COMPOSITION FOR FLUORIDATING TEETH 审中-公开
    用于氟化剂的双组分硬度组合物

    公开(公告)号：WO1997016160A1

    公开(公告)日：1997-05-09

    申请号：PCT/US1996017364

    申请日：1996-10-29

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： COLGATE-PALMOLIVE COMPANY ,  BLAKE-HASKINS, John, C. ,  COLLIGAN, Mary, L. ,  MANDANAS, Benjamin, Y. ,  GAFFAR, Abdul

    IPC: A61K07/16

    CPC classification number: A61Q11/00 ,  A61K8/21 ,  A61K8/73 ,  A61K2800/88

    Abstract: A method is disclosed for fluoridating teeth using a two-component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof are the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and the second dentifrice compounds are maintained separate from the other until mixed for application to teeth.

    Abstract translation: 公开了一种使用双组分洁牙剂系统对牙齿进行氟化的方法，其中第一组分是含水载色剂中含有氟离子可释放的可水解复合氟化物如氟硅酸钠的稳定的半固体可挤出洁齿剂组合物，其中黄原胶 胶是主要的增稠剂，甘油，山梨糖醇或其混合物是保湿剂，第二组分是含有钙离子可释放化合物的半固体可挤出洁牙剂组合物和含有黄原胶作为主要增稠剂的水性载体中的研磨剂 和甘油，山梨糖醇或其混合物作为保湿剂。 第一和第二洁牙剂化合物与另一种洁牙剂化合物保持分开，直到混合以施用于牙齿。

    PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE
    3.
    发明申请
    PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE 审中-公开
    视觉清晰凝胶密度的制备

    公开(公告)号：WO1996038123A1

    公开(公告)日：1996-12-05

    申请号：PCT/US1996007688

    申请日：1996-05-23

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： COLGATE-PALMOLIVE COMPANY ,  MANDANAS, Benjamin, Y. ,  BAINES, Eric ,  MANDADI, Prakasarao

    IPC: A61K07/16

    CPC classification number: A61K8/042 ,  A61K8/24 ,  A61K8/25 ,  A61K8/345 ,  A61K8/73 ,  A61K8/8164 ,  A61K2800/262 ,  A61Q11/00

    Abstract: Preparation of a visually clear gel dentifrice comprising a precipitated silica polishing agent having a refractive index of about 1.44, a water-swellable synthetic anionic polycarboxylate polymer which is added in solid form and a liquid vehicle comprising water and sorbitol wherein (a) when the total water content is above 30 % to about 33 % by weight of said dentifrice, sorbitol on a neat basis is present in amount of above 30 % to about 36 % by weight of said dentifrice, (b) when the total water content is about 27 % up to below 30 % by weight of said dentifrice, sorbitol on a neat basis is present in amount of about 20 % up to below 30 % by weight of said dentifrice and other humectant if present, is in neat amount of up to 15 % by weight of said dentifrice and also adding to said liquid vehicle about 1-4 % by weight of dentifrice of solid water-swellable synthetic anionic polycarboxylate polymer.

    Abstract translation: 制备视觉透明的凝胶洁齿剂，其包含折射率为约1.44的沉淀二氧化硅抛光剂，以固体形式加入的水溶胀性合成阴离子聚羧酸酯聚合物和包含水和山梨糖醇的液体载剂，其中（a）当总计 水含量高于所述洁齿剂的30重量％至约33重量％，纯净的山梨糖醇以所述洁齿剂重量的30重量％至约36重量％的量存在，（b）当总含水量为约27 ％至高于所述洁齿剂的30重量％以下，纯净的山梨糖醇的存在量为所述洁齿剂和其它湿润剂（如果存在）的约20重量％至低于30重量％，纯度高达15重量％ 的所述洁齿剂并且还向所述液体载体中加入约1-4重量％的固体水溶胀性合成阴离子聚羧酸酯聚合物的洁齿剂。

    DUAL COMPONENT DENTIFRICE COMPOSITION FOR FLUORIDATING TEETH
    6.
    发明公开
    DUAL COMPONENT DENTIFRICE COMPOSITION FOR FLUORIDATING TEETH 失效
    双组分牙齿组合物技术加氟牙齿

    公开(公告)号：EP0858316A1

    公开(公告)日：1998-08-19

    申请号：EP96937076.0

    申请日：1996-10-29

    Applicant: Colgate-Palmolive Company

    Inventor： BLAKE-HASKINS, John, C. ,  COLLIGAN, Mary, L. ,  MANDANAS, Benjamin, Y. ,  GAFFAR, Abdul

    IPC: A61K8 ,  A61Q11

    CPC classification number: A61Q11/00 ,  A61K8/21 ,  A61K8/73 ,  A61K2800/88

    Abstract: A method is disclosed for fluoridating teeth using a two-component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof are the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and the second dentifrice compounds are maintained separate from the other until mixed for application to teeth.

    PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE
    7.
    发明授权
    PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE 失效
    产生透明的凝胶牙膏

    公开(公告)号：EP0828475B1

    公开(公告)日：2001-10-04

    申请号：EP96920482.5

    申请日：1996-05-23

    Applicant: Colgate-Palmolive Company

    Inventor： MANDANAS, Benjamin, Y. ,  BAINES, Eric ,  MANDADI, Prakasarao

    IPC: A61K7/16

    CPC classification number: A61K8/042 ,  A61K8/24 ,  A61K8/25 ,  A61K8/345 ,  A61K8/73 ,  A61K8/8164 ,  A61K2800/262 ,  A61Q11/00

    Abstract: Preparation of a visually clear gel dentifrice comprising a precipitated silica polishing agent having a refractive index of about 1.44, a water-swellable synthetic anionic polycarboxylate polymer which is added in solid form and a liquid vehicle comprising water and sorbitol wherein (a) when the total water content is above 30 % to about 33 % by weight of said dentifrice, sorbitol on a neat basis is present in amount of above 30 % to about 36 % by weight of said dentifrice, (b) when the total water content is about 27 % up to below 30 % by weight of said dentifrice, sorbitol on a neat basis is present in amount of about 20 % up to below 30 % by weight of said dentifrice and other humectant if present, is in neat amount of up to 15 % by weight of said dentifrice and also adding to said liquid vehicle about 1-4 % by weight of dentifrice of solid water-swellable synthetic anionic polycarboxylate polymer.

    PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE
    8.
    发明公开
    PREPARATION OF A VISUALLY CLEAR GEL DENTIFRICE 失效
    产生透明的凝胶牙膏

    公开(公告)号：EP0828475A1

    公开(公告)日：1998-03-18

    申请号：EP96920482.0

    申请日：1996-05-23

    Applicant: Colgate-Palmolive Company

    Inventor： MANDANAS, Benjamin, Y. ,  BAINES, Eric ,  MANDADI, Prakasarao

    IPC: A61K8 ,  A61Q11

    CPC classification number: A61K8/042 ,  A61K8/24 ,  A61K8/25 ,  A61K8/345 ,  A61K8/73 ,  A61K8/8164 ,  A61K2800/262 ,  A61Q11/00

    Abstract: Preparation of a visually clear gel dentifrice comprising a precipitated silica polishing agent having a refractive index of about 1.44, a water-swellable synthetic anionic polycarboxylate polymer which is added in solid form and a liquid vehicle comprising water and sorbitol wherein (a) when the total water content is above 30 % to about 33 % by weight of said dentifrice, sorbitol on a neat basis is present in amount of above 30 % to about 36 % by weight of said dentifrice, (b) when the total water content is about 27 % up to below 30 % by weight of said dentifrice, sorbitol on a neat basis is present in amount of about 20 % up to below 30 % by weight of said dentifrice and other humectant if present, is in neat amount of up to 15 % by weight of said dentifrice and also adding to said liquid vehicle about 1-4 % by weight of dentifrice of solid water-swellable synthetic anionic polycarboxylate polymer.

    USE OF A DUAL COMPONENT DENTIFRICE COMPOSITION FOR FLUORIDATING TEETH
    9.
    发明授权
    USE OF A DUAL COMPONENT DENTIFRICE COMPOSITION FOR FLUORIDATING TEETH 失效
    使用两部分型牙组合物技术加氟牙

    公开(公告)号：EP0858316B1

    公开(公告)日：2001-12-19

    申请号：EP96937076.6

    申请日：1996-10-29

    Applicant: Colgate-Palmolive Company

    Inventor： BLAKE-HASKINS, John, C. ,  COLLIGAN, Mary, L. ,  MANDANAS, Benjamin, Y. ,  GAFFAR, Abdul

    IPC: A61K7/16 ,  A61K7/18

    CPC classification number: A61Q11/00 ,  A61K8/21 ,  A61K8/73 ,  A61K2800/88

    Abstract: A method is disclosed for fluoridating teeth using a two-component dentifrice system in which the first component is stable, semi-solid, extrudable dentifrice composition containing a fluoride ion releasable hydrolyzable complex fluoride compound such as sodium fluorosilicate, in an aqueous vehicle in which xanthan gum is the major thickening agent and glycerin, sorbitol or mixtures thereof are the humectant, and the second component is a semi-solid, extrudable dentifrice composition containing a calcium ion releasable compound and an abrasive in an aqueous vehicle containing xanthan gum as the major thickener and glycerin, sorbitol or mixtures thereof as the humectant. The first and the second dentifrice compounds are maintained separate from the other until mixed for application to teeth.

    STRIPED DENTIFRICE
    10.
    发明公开
    STRIPED DENTIFRICE 有权
    条纹牙膏

    公开(公告)号：EP1137392A1

    公开(公告)日：2001-10-04

    申请号：EP99963048.6

    申请日：1999-12-08

    Applicant: Colgate-Palmolive Company

    Inventor： BURKE, Michael, R. ,  DeBONDT, Veerle ,  DELVENNE, Jean-Paul ,  PLEN, Tessa ,  TAMBS, Gary ,  MANDANAS, Benjamin, Y. ,  MANDADI, Prakasarao ,  WONG, Mike

    IPC: A61K7/16

    CPC classification number: A61Q11/00 ,  A61K8/02 ,  A61K8/0237 ,  A61K2800/88

    Abstract: A method for forming a striped dentifrice wherein a first dentifrice which appears unstriped when stored in a container having sidewalls at least a portion of which is transparent, is transformed into a striped dentifrice upon extrusion from the container, which method comprises storing the first dentifrice in the container provided with discharge means and striping means within the discharge means, sequentially filling the container with a striping dentifrice having a color which distinguishes the striping dentifrice from the first dentifrice, the striping dentifrice being stored in an area of the container separate from the first dentifrice, followed by filling the container with the first dentifrice, apllying pressure on the dentifrices to cause the striping dentifrice to be applied to the first dentifrice within the container area in which the second dentifrice is stored and be simultaneously extruded together from the container, so that upon extrusion, the extruded dentifrice appears to have been magically transformed into a striped body.

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