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公开(公告)号:DE69632543T2
公开(公告)日:2005-05-25
申请号:DE69632543
申请日:1996-12-13
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: LIVACHE THIERRY , ROGET ANDRE , TEOULE ROBERT
Abstract: A method for preparing a copolymer of general formula (I) by electrochemically copolymerising a compound of general formula (II) with a compound [A], wherein [A] is a monomeric unit of a polymer capable of being produced by electrochemical copolymerisation, [B] is a side group that may be a monomer or a polymer and is bound to unit [A] by a covalent bond or via a spacer arm, and x and y are integers of a least 1. Said method includes a treatment enabling the surface reactivity of said copolymer to be reduced.
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公开(公告)号:AT67768T
公开(公告)日:1991-10-15
申请号:AT87400739
申请日:1987-04-03
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: MOLKO DIDIER , SCHULHOF JEAN-CLAUDE , TEOULE ROBERT
IPC: C07H19/067 , C07H19/06 , C07H19/073 , C07H19/10 , C07H19/16 , C07H19/173 , C07H19/20 , C07H21/00 , C07H21/04 , C07H19/12
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公开(公告)号:FR1500055A
公开(公告)日:1967-11-03
申请号:FR66100
申请日:1966-06-20
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: TEOULE ROBERT
IPC: G01N15/08
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公开(公告)号:DE69218958D1
公开(公告)日:1997-05-15
申请号:DE69218958
申请日:1992-10-07
Inventor: DUPLAA ANNE-MARIE , GASPARUTTO DIDIER , LIVACHE THIERRY , MOLKO DIDIER , TEOULE ROBERT
IPC: C07H21/02
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公开(公告)号:DE3751947T2
公开(公告)日:1997-05-07
申请号:DE3751947
申请日:1987-04-03
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: MOLKO DIDIER , SCHULHOF JEAN-CLAUDE , TEOULE ROBERT
IPC: C07H19/067 , C07H19/06 , C07H19/073 , C07H19/10 , C07H19/16 , C07H19/173 , C07H19/20 , C07H21/00 , C07H21/04
Abstract: The derivatives correspond to the formula: in which B denotes a radical derived from guanine, cytosine or adenine in which the exocyclic NH group is protected by the group with R denoting a hydrogen atom or an alkyl radical and R denoting a hydrogen atom, an alkyl radical, an alkoxy radical or an optionally substituted aryloxy radical, R denotes a hydrogen atom, the dimethoxytrityl radical or the radical: R denotes a hydrogen atom, the radical of formula: or a radical which is suitable for the synthesis of polynucleotides, and R denotes a hydrogen atom or the hydroxyl radical OH, protected or otherwise.
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公开(公告)号:FR2621591B1
公开(公告)日:1990-01-12
申请号:FR8713911
申请日:1987-10-08
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: MOLKO DIDIER , ROGET ANDRE , SCHULOUF JEAN-CLAUDE , TEOULE ROBERT
IPC: C07H19/067 , C07H19/06 , C07H19/073 , C07H19/10 , C07H21/00
Abstract: Nucleoside derivatives and their use for the synthesis of oligonucleotides. … These derivatives correspond to the formula: … … in which R denotes the radical of formula:… -CO-CH2-C(R R )-R … in which R and R , which may be identical or different, denote a hydrogen atom or an alkyl radical, and R denotes an optionally substituted aryl radical, R denotes a hydrogen atom, the dimethoxytrityl radical or the radical R , R denotes a hydrogen atom, the radical R or a radical suited for the synthesis of polynucleotides, and R denotes a hydrogen atom or the protected or unprotected hydroxyl radical. … R may be the radical -CO-CH2-CH2-C6H5.
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公开(公告)号:FR2476092A1
公开(公告)日:1981-08-21
申请号:FR8003700
申请日:1980-02-20
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: DERBYSHIRE ROGER , GUY ANDRE , MOLKO DIDIER , ROGET ANDRE , TEOULE ROBERT
Abstract: Phosphotriester linkages in the synthesis of polynucleotides from nucleotides and/or polynucleotides are formed using, as the condensation agent, a benzotriaxolyl N-oxytris dialkylamino phosphonium salt of formula (I) (where R1 and R2 is alkyl; A- is a not very nucleophilic anion). Pref. process uses (I; A- is PF6-; R1 and R2 is CH3). Less side reactions, better yields and it is possible to synthesise relatively long chain polynucleotides.
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公开(公告)号:DE69634233D1
公开(公告)日:2005-03-03
申请号:DE69634233
申请日:1996-11-14
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: CAILLAT PATRICE , NICOLAS GERARD , TEOULE ROBERT
IPC: H01L21/306 , B01J19/00 , C40B40/06 , C40B40/10 , G01N27/403 , G01N33/00 , H01L23/52
Abstract: Semi-conductor units (110-113) are mounted on a substrate (100) and are individually tested. Electrodes (110a-113b) of different units which pass the test are connected together in respective groups by networks (117a,117b) according to a circuit plan, and the electrodes in each group in turn are coated by submerging the assembly in an appropriate bath and applying an electric potential to the corresponding network to induce an electrochemical reaction at the electrodes.
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公开(公告)号:DE69632543D1
公开(公告)日:2004-06-24
申请号:DE69632543
申请日:1996-12-13
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: LIVACHE THIERRY , ROGET ANDRE , TEOULE ROBERT
Abstract: A method for preparing a copolymer of general formula (I) by electrochemically copolymerising a compound of general formula (II) with a compound [A], wherein [A] is a monomeric unit of a polymer capable of being produced by electrochemical copolymerisation, [B] is a side group that may be a monomer or a polymer and is bound to unit [A] by a covalent bond or via a spacer arm, and x and y are integers of a least 1. Said method includes a treatment enabling the surface reactivity of said copolymer to be reduced.
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公开(公告)号:DE3751947D1
公开(公告)日:1996-12-12
申请号:DE3751947
申请日:1987-04-03
Applicant: COMMISSARIAT ENERGIE ATOMIQUE
Inventor: MOLKO DIDIER , SCHULHOF JEAN-CLAUDE , TEOULE ROBERT
IPC: C07H19/067 , C07H19/06 , C07H19/073 , C07H19/10 , C07H19/16 , C07H19/173 , C07H19/20 , C07H21/00 , C07H21/04
Abstract: The derivatives correspond to the formula: in which B denotes a radical derived from guanine, cytosine or adenine in which the exocyclic NH group is protected by the group with R denoting a hydrogen atom or an alkyl radical and R denoting a hydrogen atom, an alkyl radical, an alkoxy radical or an optionally substituted aryloxy radical, R denotes a hydrogen atom, the dimethoxytrityl radical or the radical: R denotes a hydrogen atom, the radical of formula: or a radical which is suitable for the synthesis of polynucleotides, and R denotes a hydrogen atom or the hydroxyl radical OH, protected or otherwise.
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