公开(公告)号：CA2802799A1

公开(公告)日：2012-02-16

申请号：CA2802799

申请日：2011-06-09

Applicant: CONOCOPHILLIPS COMPANY IP SERVICES GROUP ,  UNIV KANSAS

Inventor： GUAN HUILI ,  BERKLAND CORY ,  MORADI-ARAGHI AHMAD ,  LIANG JENN-TAI ,  ZORNES DAVID R ,  NEEDHAM RILEY B ,  HEDGES JAMES H ,  CHENG MIN ,  JOHNSON JAMES P ,  SCULLY FAYE L

IPC: C08J3/075 ,  C09K8/70

Abstract: The invention is directed to delayed gelation agents comprising a degradable polymeric cage containing therein one or more gelation agents. The cage degrades in situ, e.g, in an oil reservoir, thus releasing the gelation agent(s), which can then crosslink second polymers in situ to form a gel.

公开(公告)号：CA2753522A1

公开(公告)日：2010-11-18

申请号：CA2753522

申请日：2010-05-14

Applicant: CONOCOPHILLIPS COMPANY IP SERVICES GROUP ,  UNIV KANSAS

Inventor： MORADIARAGHI AHMAD ,  HEDGES JAMES H ,  ZORNES DAVID R ,  NEEDHAM RILEY B ,  GUAN HUILI ,  LIANG JENN-TAI ,  BERKLAND CORY ,  JOHNSON JAMES P ,  CHENG MIN ,  SCULLY FAYE L

IPC: C09K8/68

Abstract: The invention is directed to crosslinked water-soluble swellable polymers, methods for making same and their various uses. More particularly, the invention relates to a composition comprising expandable polymeric particles being made with 0.1-5% hydrophobic monomers and labile crosslinkers and stable crosslinkers, said particles mixed with a fluid. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into a well and when the heat and/or pH of the target zones in the formation cause degradation of the labile crosslinker and when the particle expands, the hydrophobic groups associate to form a hydrophobically associative polymer, thus diverting water to lower permeability regions and improving oil recovery.

公开(公告)号：CA2758391A1

公开(公告)日：2010-12-23

申请号：CA2758391

申请日：2010-06-14

Applicant: CONOCOPHILLIPS COMPANY IP SERVICES GROUP ,  UNIV KANSAS

Inventor： MORADIARAGHI AHMAD ,  HEDGES JAMES HERBERT ,  ZORNES DAVID RUSSELL ,  NEEDHAM RILEY BYRAN ,  GUAN HUILI ,  LIANG JENN-TAI ,  BERKLAND CORY ,  JOHNSON JAMES PRYOR ,  CHENG MIN ,  SCULLY FAYE LYNN

IPC: C08L33/26 ,  C08J3/24 ,  C08J9/228 ,  C08K5/20 ,  C08L39/00 ,  C09K8/588

Abstract: The invention is directed to long lasting crosslinked water-soluble swellable polymers, methods for making same, and their uses. More particularly, the invention relates to a composition comprising expandable polymeric particles having cationic sites as well as labile crosslinkers and stable crosslinkers, said particle mixed with a fluid. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into a target zones in the reservoirs and when the heat and/or pH of the reservoir cause degradation of the labile crosslinker and when the particle expands, the cationic sites in the polymer adsorb to the rock in the formation, thus diverting water to lower permeability regions and improving oil recovery. However, many other uses are possible.

公开(公告)号：MX2011013343A

公开(公告)日：2012-04-30

申请号：MX2011013343

申请日：2010-06-09

Applicant: CONOCOPHILLIPS COMPANY IP SERVICES GROUP

Inventor： ZORNES DAVID RUSSELL ,  MORADIARAGHI AHMAD ,  HEDGES JAMES HERBERT ,  NEEDHAM RILEY BYRAN ,  GUAN HUILI ,  LIANG JENN-TAI ,  BERKLAND CORY ,  CHENG MIN ,  SCULLY FAYE LYNN

IPC: C08F20/06 ,  C08F26/00

Abstract: La invención está dirigida a polímeros expandibles solubles en agua entrelazados estables y métodos para hacer los mismos. De modo más particular la invención se refiere a una composición que comprende partículas poliméricas expandibles que tienen sitios aniónicos y entrelazadores lábiles y entrelazadores estables, la partícula mezclada con un fluido y un entrelazador catiónico que es capaz de entrelazar de manera adicional la partícula a la degradación del entrelazador lábil y la exposición de los sitios aniónicos para formar un gel. Un uso particularmente importante es como un fluido de inyección en la producción de petróleo, en donde las partículas poliméricas expandibles son inyectadas dentro de la zona de objetivo y cuando el calor y/o el pH adecuado de la zona de objetivo ocasionan la degradación del entrelazador lábil y la partícula se expande, el entrelazador catiónico entrelaza el polímero para formar un gel, derivando por tanto el agua hacia las regiones de menor permeabilidad y mejorando la recuperación de petróleo.

公开(公告)号：WO2008055151A9

公开(公告)日：2008-10-23

申请号：PCT/US2007082989

申请日：2007-10-30

Applicant: UNIV KANSAS ,  UNIV KANSAS MEDICAL CENTER ,  BERKLAND CORY ,  STEHNO-BITTEL LISA A ,  SIAHAAN TERUNA

Inventor： BERKLAND CORY ,  STEHNO-BITTEL LISA A ,  SIAHAAN TERUNA

IPC: C12N5/00

CPC classification number: C12N5/0676 ,  A61K35/39 ,  A61L27/18 ,  A61L27/3882 ,  A61L27/3895 ,  C12N5/0677 ,  C12N2509/00 ,  C12N2533/40 ,  C12N2535/10 ,  C08L67/04

Abstract: An implantable biomaterial scaffold having islet cells or small islet cell clusters attached thereto in a multilayer. The cells are derived by enzymatic dispersion and/or calcium depletion of large adult intact islets.

公开(公告)号：WO2009049230A8

公开(公告)日：2010-07-08

申请号：PCT/US2008079611

申请日：2008-10-10

Applicant: UNIV KANSAS ,  DETAMORE MICHAEL ,  SINGH MILLIND ,  SCURTO AARON M ,  BERKLAND CORY

Inventor： DETAMORE MICHAEL ,  SINGH MILLIND ,  SCURTO AARON M ,  BERKLAND CORY

IPC: A61L27/26 ,  A61F2/00 ,  A61K45/00

CPC classification number: C12N5/0075 ,  C12N2533/10 ,  C12N2533/40

Abstract: A tissue engineering scaffold for growing cells can include a plurality of biocompatible microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells. The biocompatible microspheres can include first and second sets of microspheres. The first set of microspheres can have a first characteristic, and a first predetermined spatial distribution with respect to the three-dimensional matrix. The second set of microspheres can have a second characteristic that is different from the first characteristic, and a second predetermined spatial distribution that is different from the first predetermined spatial distribution with respect to the three - dimensional matrix. The first and second characteristics can selected a composition, polymer, particle size, particle size distribution, type of bioactive agent, type of bioactive agent combination, bioactive agent concentration, amount of bioactive agent, rate of bioactive agent release, mechanical strength, flexibility, rigidity, color, radiotranslucency, radiopaqueness, or the like.

Abstract translation: 用于生长细胞的组织工程支架可以包括连接在一起以形成三维基质的多个生物相容性微球。 基质可以包括用于生长细胞的多个孔。 生物相容性微球可以包括第一组和第二组微球。 第一组微球可以具有第一特性，并且相对于三维矩阵具有第一预定空间分布。 第二组微球可以具有不同于第一特性的第二特性和与第一预定空间分布相对于三维矩阵不同的第二预定空间分布。 第一和第二特征可以选择组合物，聚合物，粒度，粒度分布，生物活性剂的类型，生物活性剂组合的类型，生物活性剂浓度，生物活性剂的量，生物活性剂释放速率，机械强度，柔韧性， 刚度，颜色，辐射透明度，无线电等等。

公开(公告)号：EP2126281A4

公开(公告)日：2014-08-27

申请号：EP07841636

申请日：2007-08-30

Applicant: UNIV KANSAS

Inventor： BERKLAND CORY ,  CORDOVA MARY ,  LIANG JENN-TAI ,  WILLHITE G PAUL

IPC: E21B43/00 ,  C09K8/512

CPC classification number: C09K8/512 ,  C09K2208/10

公开(公告)号：EP2542248A4

公开(公告)日：2013-04-17

申请号：EP11751292

申请日：2011-03-02

Applicant: UNIV KANSAS

Inventor： BERKLAND CORY ,  MOHAMMADI ZAHRA

IPC: A61K31/785

CPC classification number: A61K47/48076 ,  A61K9/0019 ,  A61K9/0056 ,  A61K31/785 ,  A61K47/547 ,  A61K47/58 ,  A61K47/595 ,  C08F8/00 ,  C08F18/22 ,  C08F26/02 ,  C08F126/02 ,  C08F2810/20 ,  C08G69/10 ,  C08G69/48 ,  C08G2210/00

Abstract: Compositions and methods for making a composition comprising a polymer and one or more chelators covalently coupled to polymer, wherein the one or more chelators has a benzene ring with more than one hydroxyl group at any position that is free, or a derivative of the chelator, or a salt of the chelator and methods of use.

公开(公告)号：WO2014130250A2

公开(公告)日：2014-08-28

申请号：PCT/US2014014985

申请日：2014-02-06

Applicant: CONOCOPHILLIPS CO ,  UNIV KANSAS

Inventor： GUAN HUILI ,  BERKLAND CORY ,  MORADI-ARAGHI AHMED ,  LIANG JENN-TAI ,  CHRISTIAN TERRY M ,  NEEDHAM RILEY B ,  HEDGES JAMES H ,  CHENG MIN ,  SCULLY FAYE L

IPC: C09K8/594 ,  E21B43/16

CPC classification number: C09K8/588 ,  C08F220/56 ,  C08F2800/10 ,  C08L33/26 ,  C09K8/594 ,  E21B33/138 ,  E21B43/164 ,  Y02P90/70

Abstract: The invention is directed to polymers that self-crosslink at acidic pH or can be crosslinked by phenolic agents in brine. Such polymers have lower viscosity and can be pumped deep into reservoirs, where they will cross link in situ, thus increasing their viscosity and/or form a gel and blocking thief zones. Methods of making and using such polymers are also provided.

Abstract translation: 本发明涉及在酸性pH下自交联或可在盐水中由酚类试剂进行交联的聚合物。 这样的聚合物具有较低的粘度并且可以深入泵入储层，在那里它们将原位交联，从而增加其粘度和/或形成凝胶并阻止小偷区。 还提供了制备和使用这些聚合物的方法。

公开(公告)号：WO2011126921A3

公开(公告)日：2012-01-19

申请号：PCT/US2011030775

申请日：2011-03-31

Applicant: UNIV KANSAS ,  BERKLAND CORY ,  STEHNO-BITTEL LISA A ,  SIAHAAN TERUNA ,  RAMACHANDRAN KARTHIK

Inventor： BERKLAND CORY ,  STEHNO-BITTEL LISA A ,  SIAHAAN TERUNA ,  RAMACHANDRAN KARTHIK

IPC: A61L27/14 ,  A61K35/12 ,  A61K35/39 ,  A61L27/18 ,  A61L27/38

CPC classification number: C12N5/0677 ,  A61K35/39 ,  A61K45/06 ,  A61L27/18 ,  A61L27/3882 ,  A61L27/3895 ,  C12N5/0676 ,  C12N2509/00 ,  C12N2533/40 ,  C12N2535/10 ,  C08L67/04

Abstract: A scaffold having islet cells or small islet cell clusters attached thereto in a multilayer, and a micro-mold having divots for culturing islets, wherein islet formation is influenced by the shape and dimensions of the divots are disclosed.

Abstract translation: 具有在多层中附着有胰岛细胞或小胰岛细胞簇的支架，以及具有用于培养胰岛的细胞的微型模具，其中，胰岛形成受到影像的形状和尺寸的影响。