Means and methods for targeted x-ray therapy

    公开(公告)号:US10265510B2

    公开(公告)日:2019-04-23

    申请号:US15503006

    申请日:2015-08-12

    Abstract: The present invention provides a method for activating a pro-drug in vivo comprising the steps of: (a) administering a pro-drag to a subject; (b) locating a target site which has been at least partially dosed with the pro-drug at a predetermined concentration; and (d) exposing the target site to X-ray radiation. The step of exposing the target site to X-ray radiation is characterized by providing a converging X-ray of a controllable waist, substantially uniform at the target site, sufficient to convert the pro-drug to an active drug, while the X-ray photon dosage at the target site is higher than the X-ray photon dosage at an adjacent non target site.

    X-RAY REFLECTIVE LENS ARRANGEMENT
    4.
    发明申请
    X-RAY REFLECTIVE LENS ARRANGEMENT 有权
    X射线反射镜

    公开(公告)号:US20150248942A1

    公开(公告)日:2015-09-03

    申请号:US14430683

    申请日:2013-09-01

    Abstract: An X-ray lens arrangement for forming a radiation pattern as a focal track is disclosed. The pattern comprises at least one 3-dimensional focal track of radiation. The aforesaid lens arrangement has a main axis passing through intensity weighted centroids of the X-ray source and the pattern. The lens arrangement includes at least one reflecting surface of continuously varying Rowland arcs. Each point belonging to the focal track is linked to each elemental point composing an emitting surface of said source by a corresponding Rowland arc.

    Abstract translation: 公开了一种用于形成辐射图案作为焦点轨迹的X射线透镜装置。 该图案包括至少一个辐射的三维焦点轨迹。 上述透镜装置具有通过X射线源的强度加权质心和图案的主轴。 透镜装置包括连续变化的罗兰弧的至少一个反射表面。 属于焦点轨迹的每个点通过相应的罗兰弧连接到构成所述源的发射表面的每个元素点。

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