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    A STANDARD OF CARE PROTOCOL FOR REDUCING LONG AND SHORT-TERM ADVERSE EFFECTS CAUSED BY RADIOTHERAPY OR RADIOSURGERY TREATMENT
    1.
    发明申请
    A STANDARD OF CARE PROTOCOL FOR REDUCING LONG AND SHORT-TERM ADVERSE EFFECTS CAUSED BY RADIOTHERAPY OR RADIOSURGERY TREATMENT 审中-公开
    “放射治疗”或“放射治疗”治疗导致长期和短期不良反应的护理标准

    公开(公告)号：WO2015087319A1

    公开(公告)日：2015-06-18

    申请号：PCT/IL2014/051065

    申请日：2014-12-07

    Applicant: CONVERGENT R.N.R LTD

    Inventor： BAR-DAVID, Aharon ,  MARKOVICH, Miri ,  BURSHTEIN, Zeev ,  HAREL, Zeev

    IPC: A61N5/10

    CPC classification number: A61N5/1077 ,  A61N5/1031 ,  A61N5/1048 ,  A61N5/1084

    Abstract: A standard of care protocol for increasing efficiency of a radiotherapy or radiosurgery treatment and reducing the treatment's side effects by radiating with a converging x-ray beam source emitting a converging x-ray beam (102) towards at least one volume of treatment (VOT) (103) within a patient's body; the beam is passing through at least one organ preceding said VOT (PO) (105) and at least one organ distal to said VOT (DO) (106); the VOT is receiving, on average, at least 80% of maximum dose whilst thr PO and DO are receiving, on average, no more than 40% of the maximum dose.

    Abstract translation: 一种用于提高放射治疗或放射外科治疗效率的护理方案的标准，并且通过用朝向至少一个治疗体积（VOT）发射会聚的X射线束（102））的会聚x射线束源辐射来减少治疗的副作用， （103）在患者体内; 光束穿过所述VOT（PO）（105）之前的至少一个器官和远离所述VOT（DO）（106）的至少一个器官; VOT平均接受最大剂量的至少80％，而PO和DO接受平均不超过最大剂量的40％。

    SCANNING BREAST EXAMINATION DEVICE AND PROCEDURE
    2.
    发明申请
    SCANNING BREAST EXAMINATION DEVICE AND PROCEDURE 审中-公开

    公开(公告)号：WO2020170245A1

    公开(公告)日：2020-08-27

    申请号：PCT/IL2020/050181

    申请日：2020-02-18

    Applicant: CONVERGENT R.N.R LTD.

    Inventor： HAREL, Zeev ,  BAR-DAVID, Aharon ,  BURSHTEIN, Zeev

    IPC: A61B6/00 ,  A61B10/00 ,  A61B90/17 ,  A61N5/10

    Abstract: An arrangement for securing a female breast during a medical procedure comprises a receptacle conformed to a shape of the female breast. The receptacle is configured to be vacuumed such that the female breast is releasably securable within the receptacle. The arrangement comprises a first and second concave shell-like articles; the first article is sieve and forms the receptacle. The first article is nested into the second article such that an internal cavity is formed therebetween. The female breast when placed into the receptacle is securable therewithin by exhausting air from the internal cavity and pneumatically attaching tissues of the female breast to the first sieve article.

    X-RAY REFLECTIVE LENS ARRANGEMENT
    3.
    发明申请
    X-RAY REFLECTIVE LENS ARRANGEMENT 审中-公开
    X射线反射镜

    公开(公告)号：WO2014045273A1

    公开(公告)日：2014-03-27

    申请号：PCT/IL2013/050739

    申请日：2013-09-01

    Applicant: CONVERGENT R.N.R LTD

    Inventor： BAR-DAVID, Aharon ,  BURSHTEIN, Zeev ,  HAREL, Zeev

    IPC: G02B17/00 ,  G06K1/06

    CPC classification number: G21K1/062 ,  A61N5/1042 ,  A61N5/1084 ,  A61N2005/1091 ,  A61N2005/1095 ,  G21K5/04 ,  G21K2201/064

    Abstract: An X-ray lens arrangement for forming a radiation pattern as a focal track is disclosed. The pattern comprises at least one 3-dimensional focal track of radiation. The aforesaid lens arrangement has a main axis passing through intensity weighted centroids of the X- ray source and the pattern. The lens arrangement includes at least one reflecting surface of continuously varying Rowland arcs. Each point belonging to the focal track is linked to each elemental point composing an emitting surface of said source by a corresponding Rowland arc.

    Abstract translation: 公开了一种用于形成辐射图案作为焦点轨迹的X射线透镜装置。 该图案包括至少一个辐射的三维焦点轨迹。 上述透镜装置具有通过X射线源的强度加权质心和图案的主轴。 透镜装置包括连续变化的罗兰弧的至少一个反射表面。 属于焦点轨迹的每个点通过相应的罗兰弧连接到构成所述源的发射表面的每个元素点。

    MEANS AND METHODS FOR TARGETED X-RAY THERAPY
    4.
    发明申请
    MEANS AND METHODS FOR TARGETED X-RAY THERAPY 审中-公开
    用于靶向X射线治疗的方法和方法

    公开(公告)号：WO2016024279A1

    公开(公告)日：2016-02-18

    申请号：PCT/IL2015/050824

    申请日：2015-08-12

    Applicant: CONVERGENT R.N.R LTD

    Inventor： HAREL, Zeev ,  BURSHTEIN ZEEV, Zeev ,  BAR-DAVID, Aharon ,  MARKOVICH, Miri

    IPC: A61N5/10 ,  A61K41/00

    CPC classification number: A61M37/00 ,  A61K9/0009 ,  A61K41/00 ,  A61K41/0052 ,  A61M2037/0007 ,  A61N5/10 ,  A61N2005/1091 ,  A61N2005/1098

    Abstract: The present invention provides a method for activating a pro-drug in vivo comprising the steps of: (a) administering a pro-drag to a subject; (b) locating a target site which has been at least partially dosed with the pro-drug at a predetermined concentration; and (d) exposing the target site to X-ray radiation. The step of exposing the target site to X-ray radiation is characterized by providing a converging X-ray of a controllable waist, substantially uniform at the target site, sufficient to convert the pro-drug to an active drug, whilst the X-ray photon dosage at the target site is higher than the X-ray photon dosage at an adjacent non target site.

    Abstract translation: 本发明提供了一种在体内活化前药的方法，包括以下步骤：（a）向受试者施用阻遏物; （b）将至少部分给予前药的目标部位定位在预定浓度下; 和（d）将目标部位暴露于X射线辐射。 将目标部位暴露于X射线辐射的步骤的特征在于提供可控腰部的会聚X射线，其在目标部位基本均匀，足以将前药转化为活性药物，同时X射线 目标位点的光子剂量高于相邻非靶位点处的X射线光子剂量。

    USING FOCUSED CONVERGING X-RAYS FOR IMAGING
    5.
    发明申请
    USING FOCUSED CONVERGING X-RAYS FOR IMAGING 审中-公开
    使用聚焦X射线成像

    公开(公告)号：WO2015140796A1

    公开(公告)日：2015-09-24

    申请号：PCT/IL2015/050281

    申请日：2015-03-16

    Applicant: CONVERGENT R.N.R LTD

    Inventor： BAR-DAVID, Aharon ,  BURSHTEIN, Zeev ,  KELLER, Avigail ,  HAREL, Zeev

    IPC: G21K1/06 ,  G21K5/04 ,  G01N23/02

    CPC classification number: G01N23/046 ,  G01N2223/316 ,  G21K1/067

    Abstract: An X-ray system is arranged for Imaging using converging X-rays that is produced by a converging device, for example an X-ray lens, that converges the X-rays towards a focusing point. The purpose of the system is to image a small volume at the target location with improved quality and the ability to magnify the image and obtaining additional information.

    Abstract translation: X射线系统被布置成用于使用由会聚装置（例如X射线透镜）产生的会聚X射线的成像，其将X射线会聚到聚焦点。 该系统的目的是在目标位置对较小的体积进行成像，并提高质量，并具有放大图像和获得附加信息的能力。

    Imaging-Guided Delivery of X-Ray Radiation
    8.
    发明申请
    Imaging-Guided Delivery of X-Ray Radiation 有权
    成像导向X射线辐射

    公开(公告)号：US20140348297A1

    公开(公告)日：2014-11-27

    申请号：US14457250

    申请日：2014-08-12

    Applicant: CONVERGENT R.N.R LTD

    Inventor： Zeev BURSHTEIN ,  Zeev HAREL ,  Aharon BAR-DAVID ,  Donald M. Korn

    IPC: A61N5/10 ,  G21K1/04 ,  G21K1/06 ,  A61B6/00

    CPC classification number: A61N5/1049 ,  A61B6/06 ,  A61B6/4021 ,  A61B6/4035 ,  A61B6/483 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1054 ,  A61N2005/1061 ,  A61N2005/1091 ,  A61N2005/1095 ,  G21K1/04 ,  G21K1/065 ,  G21K1/067 ,  G21K2201/064 ,  H05G1/70

    Abstract: An X-ray system comprises: (a) a source providing an X-ray diverging beam having treatment and imaging angular portions; (b) one or more lenses transforming the treatment portion of the X-ray beam into a converging beam directed to a target; (c) a first shutter located between the X-ray source and the target in the imaging portion of the X-ray radiation; the first shutter being selectively openable such that imaging portion of X-ray beam reaches the target; and (d) a detector configured to detect at least a portion of the imaging radiation after the imaging radiation has interacted with the target to provide imaging information of the target.

    Abstract translation: X射线系统包括：（a）提供具有处理和成像角部分的X射线发散光束的光源; （b）一个或多个透镜将X射线束的处理部分转换成指向靶的会聚光束; （c）在X射线辐射的成像部分中位于X射线源和靶之间的第一快门; 所述第一挡板选择性地可打开，使得X射线束的成像部分到达所述目标; 以及（d）检测器，被配置为在所述成像辐射已经与所述目标物体相互作用之后检测所述成像辐射的至少一部分，以提供所述目标的成像信息。

    X-RAY OPTICAL ARRANGEMENT
    9.
    发明申请
    X-RAY OPTICAL ARRANGEMENT 审中-公开

    公开(公告)号：WO2021059271A1

    公开(公告)日：2021-04-01

    申请号：PCT/IL2020/051039

    申请日：2020-09-23

    Applicant: CONVERGENT R.N.R LTD

    Inventor： BORUKHIN, Shirly ,  KLECKNER, Michael ,  BAR-DAVID, Aharon ,  HAREL, Zeev

    IPC: G21K1/06 ,  B23B7/00

    Abstract: A method of manufacturing burr-edged reflecting tile elements for a mosaic X-ray lens configured for forming an X-ray beam comprises steps of: (a) providing a single crystal having first and second faces thereof being parallel therebetween; single crystal having crystallographic planes thereof being parallel to first and second faces of the single crystal; the first face dedicated for reflecting an X-ray beam to be incident thereto; (b) cutting the single crystal by means of a wire electrical discharging machine normally to the main faces. The step of cutting the single crystal comprises moving a wire within a cut in direction from the second face to the first face; such that burrs configured for reflecting the X-ray beam to be incident thereto are formed on edges of the cut.

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