公开(公告)号：US20210113855A1

公开(公告)日：2021-04-22

申请号：US17071098

申请日：2020-10-15

Applicant: CONVERGENT R.N.R LTD.

Inventor： Aharon BAR-DAVID ,  Michael KLECKNER ,  Shirly BORUKHIN ,  Zeev BURSHTEIN ,  Avigail KELLER ,  Zeev HAREL

IPC: A61N5/10

Abstract: A method of evaluating a maximal dose deposited by a non-uniform X-ray beam within a medium comprising the steps of: (a) irradiating said medium by said non-uniform X-ray beam penetrating into a depth of said medium along an axis of said X-ray beam; (b) incrementally measuring a number of transversal dose distributions at successive depths along said axis; (c) determining a maximum dose within each of said number of transversal dose distributions; and (d) calculating a 1-Dimesional depth dependance of said maximal doses obtained from said number of transversal dose distributions.

公开(公告)号：US20220219011A9

公开(公告)日：2022-07-14

申请号：US17071098

申请日：2020-10-15

Applicant: CONVERGENT R.N.R LTD.

Inventor： Aharon BAR-DAVID ,  Michael KLECKNER ,  Shirly BORUKHIN ,  Zeev BURSHTEIN ,  Avigail KELLER ,  Zeev HAREL

IPC: A61N5/10

Abstract: A method of evaluating a maximal dose deposited by a non-uniform X-ray beam within a medium comprising the steps of: (a) irradiating said medium by said non-uniform X-ray beam penetrating into a depth of said medium along an axis of said X-ray beam; (b) incrementally measuring a number of transversal dose distributions at successive depths along said axis; (c) determining a maximum dose within each of said number of transversal dose distributions; and (d) calculating a 1-Dimesional depth dependance of said maximal doses obtained from said number of transversal dose distributions.

公开(公告)号：US20220351874A1

公开(公告)日：2022-11-03

申请号：US17762477

申请日：2020-09-23

Applicant: CONVERGENT R.N.R. LTD

Inventor： Shirly BORUKHIN ,  Michael KLECKNER ,  Aharon BAR-DAVID ,  Zeev HAREL

IPC: G21K1/06 ,  B23H7/02 ,  B23H9/00

Abstract: A method of manufacturing burr-edged reflecting tile elements for a mosaic X-ray lens configured for forming an X-ray beam comprises steps of: (a) providing a single crystal having first and second faces thereof being parallel therebetween; single crystal having crystallographic planes thereof being parallel to first and second faces of the single crystal; the first face dedicated for reflecting an X-ray beam to be incident thereto; (b) cutting the single crystal by means of a wire electrical discharging machine normally to the main faces. The step of cutting the single crystal comprises moving a wire within a cut in direction from the second face to the first face; such that burrs configured for reflecting the X-ray beam to be incident thereto are formed on edges of the cut.

公开(公告)号：US20220161060A1

公开(公告)日：2022-05-26

申请号：US17601868

申请日：2020-04-07

Applicant: CONVERGENT R.N.R LTD.

Inventor： Asaf ZUCK ,  Zeev BURSHTEIN ,  Aharon BAR-DAVID ,  Zeev HAREL ,  Michael KLECKNER ,  Shirly BORUKHIN

IPC: A61N5/10 ,  A61K51/12 ,  A61K51/04

Abstract: A radiotherapy treatment system and method used for conducting radiographic X-ray imaging on a target organ during radiographic treatment. The system comprises (a) an x-ray beam source configurable to deliver an X-ray beam to a target organ, (b) optical means for converging and shaping said beam to a cone-shaped X-ray beam of photons which hit the target organ simultaneously, (c) multiple high-Z nanoparticles attachable to the target organ, said high-Z nanoparticles absorbing said X-ray radiation and emitting X-ray fluorescence (XRF) photons, (d) at least one XRF detector for detecting said XRF photons ejecting out of a patient's body, and (e) control means for controlling the radiotherapy treatment procedure.
The x-ray beam is focusable on a section in the target organ where the concentration of said high-Z nanoparticles leading to a desirable emission of said XRF photons, and in case the emission of said XRF photons decreases, the x-ray beam is movable to refocus on the section in the target organ where the emission of said XRF photons is desirable.

公开(公告)号：US20210178192A1

公开(公告)日：2021-06-17

申请号：US17166064

申请日：2021-02-03

Applicant: Convergent R.N.R Ltd.

Inventor： Aharon BAR-DAVID ,  Michael KLECKNER ,  Shirly BORUKHIN ,  Zeev HAREL

IPC: A61N5/10

Abstract: A method of a radiotherapy or radiosurgery treatment comprises steps of: (a) providing a converging x-ray beam source configured for emitting a converging X-ray beam propagating along an axis thereof; (b) emitting the converging x-ray beam towards a volume of treatment (VOT) having a length along the axis of the converging X-ray beam ranging between 2 mm and 5 cm within a patient's body such that a waist portion is within the VOT; (c) propagating the beam through tissues previously located relative to the VOT (PO); the VOT per se and tissues distally located to the VOT (DO). The converging X-ray beam characterized by a convergent angle ranging between 2 and 30 degrees providing 80% to 100% of a maximum dose is received by the VOT and less than 60% of the maximum dose is received by the PO and the DO.