公开(公告)号：DE60127821D1

公开(公告)日：2007-05-24

申请号：DE60127821

申请日：2001-05-25

Applicant: CORNING INC

Inventor： LEMEE VALERIE J C ,  PECHEUL MARYLENE D M ,  MARQUE PASCAL ,  ROOT DAVID M

IPC: G01N21/77 ,  B01L3/00 ,  G01N21/64 ,  G01N21/78 ,  G01N33/50

Abstract: A system, method and device for the detection of reactions between biomolecules or cells and a second compound are disclosed. The invention utilizes a fluorescent material having a fluorescence that changes with temperature. The fluorescent material is associated with a substrate, for example, a microarray chip or microplate, preferably suitable for use in high-throughput screening of biomolecules or cells. Substrates containing the fluorescent material also can be used to compensate for temperature variations in refractive index in optical sensors.