公开(公告)号：WO2013102935A3

公开(公告)日：2013-10-03

申请号：PCT/IN2013000005

申请日：2013-01-03

Applicant: COUNCIL SCIENT IND RES

Inventor： REDDY SANTHOSH REKULA ,  PRAGATI KISHORE PRASAD ,  NAGA KIRAN CHAITHANYA INDUKURU ,  SUDALAI ARUMUGAM

IPC: C07D307/88

CPC classification number: C07D307/88 ,  C07D307/89

Abstract: The present invention disclosed herein is a novel commercially feasible, one pot synthesis of library of 3-substituted phthalides of formula I via CuCN mediated oxidative cyclization in high yield. Formula I

Abstract translation: 本文公开的本发明是一种新的商业上可行的，通过CuCN介导的高收率氧化环化的3-取代的式I化合物的文库的一锅合成。 一级方程式

公开(公告)号：IN82DE2012A

公开(公告)日：2015-05-01

申请号：IN82DE2012

申请日：2012-01-10

Applicant: COUNCIL SCIENT IND RES

Inventor： SUNITA KHANDERAO GADAKH ,  REDDY SANTHOSH REKULA ,  ARUMUGAM SUDALAI

IPC: C12N20060101

Abstract: The invention relates to a novel process for the synthesis of HIV protease inhibitors. More particularly, the invention relates to the synthesis of HIV protease inhibitorssuch as AmprenavirFosamprenavir,Darunavir and sequinavirvia synazido epoxide with high enantiomeric excessas a common intermediateobtained by Co-catalyzed hydrolytic kinetic resolution of anti-(2SR, 3SR)-3-azido-4-phenyl-l, 2-epoxybutane.

公开(公告)号：IN83DE2012A

公开(公告)日：2015-05-01

申请号：IN83DE2012

申请日：2012-01-10

Applicant: COUNCIL SCIENT IND RES

Inventor： REDDY SANTHOSH REKULA ,  PRAGATI KISHORE PRASAD ,  BRIJ BHUSHAN AHUJA ,  ARUMUGAM SUDALAI

IPC: C07C20060101

Abstract: This invention relates to cheaper and practical protocol for the construction of a wide variety of 1-Amino-2-naphthalenecarboxylic acid derivatives and their structural analogues that proceeds with high yields in a single step via intramolecular cascade cyano ene reaction.