Production of purified porcine immunoglobulins
    1.
    发明公开
    Production of purified porcine immunoglobulins 失效
    Herstellung gereinigter Schweine-Immunoglobuline。

    公开(公告)号:EP0256190A1

    公开(公告)日:1988-02-24

    申请号:EP86306450.7

    申请日:1986-08-20

    CPC classification number: C07K16/065 A61K38/00

    Abstract: A method for the continuous production of a purified immunoglobulin preparation wherein the antibodies are substantially enriched by means of a selective two-step ammonium sulfate fractionation procedure employing centrifugation and ion depletion processes. The purified immunoglobulins are subsequently commingled with condensed skim milk and spray dried. The resulting product for example is employed in the formulation of milk replacers for artificial rearing of neonatal pigs to provide the passive immunity to disease normally provided by sows' colostrum and later milk.

    Abstract translation: 用于连续生产纯化的免疫球蛋白制剂的方法,其中所述抗体通过采用离心和离子消耗过程的选择性两步硫酸铵分级方法基本上富集。 随后将纯化的免疫球蛋白与冷凝的脱脂乳混合并喷雾干燥。 所得到的产品例如用于新生猪的人造饲养的乳替代品的配制中,以提供通常由母猪的初乳和后来的牛奶提供的疾病的被动免疫。

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