公开(公告)号：EP3015547A1

公开(公告)日：2016-05-04

申请号：EP14818556.4

申请日：2014-04-24

Applicant: CJ Cheiljedang Corporation

Inventor： LEE, Ji Sun ,  LEE, Kwang Ho ,  KOH, Eun Sung ,  KIM, Hyung Joon ,  LEE, Keun Cheol ,  HWANG, Young Bin

IPC: C12N9/12 ,  C12N15/54 ,  C12N15/70 ,  C12P13/08

CPC classification number: C12N9/1247 ,  C07K14/245 ,  C12N15/70 ,  C12P13/08 ,  C12Y207/07006

Abstract: The present application relates to an L-threonine-producing microorganism and a production method for L-threonine using the same, and more specifically, to a microorganism having enhanced L-threonine productivity and a method for producing L-threonine in high yield using the same.

公开(公告)号：EP2801611A2

公开(公告)日：2014-11-12

申请号：EP13733718.4

申请日：2013-01-07

Applicant: Cj Cheiljedang Corporation

Inventor： CHEONG, Ki Yong ,  LEE, Seok Myung ,  HWANG, Young Bin ,  LEE, Keun Cheol ,  LEE, Kwang Ho

IPC: C12N1/21 ,  C12P13/22 ,  C12N15/70

CPC classification number: C12P13/227 ,  C07K14/245 ,  C12N1/20 ,  C12N9/0053 ,  C12N9/0071 ,  C12P13/08 ,  C12Y114/11 ,  Y02P20/59

Abstract: The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using same. More specifically, the present invention relates to: recombinant Escherichia coli which is more efficient in producing L-threonine or L-tryptophan by increasing the ability to produce ATP which is used as the most plentiful energy source in cells when producing L-threonine or L-tryptophan; and a method for producing L-threonine or L-tryptophan by using same.

公开(公告)号：EP3336191B1

公开(公告)日：2019-08-21

申请号：EP16792968.6

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： PARK, Hye Min ,  LEE, Baek Seok ,  LEE, Seok Myung ,  KIM, Kyungrim ,  LEE, Kwang Ho ,  CHEONG, Ki Yong ,  LEE, Keun Cheol ,  HONG, Hyeongpyo

IPC: C12N15/70 ,  C12P13/22

公开(公告)号：EP2987854A1

公开(公告)日：2016-02-24

申请号：EP14785937.5

申请日：2014-04-16

Applicant: CJ Cheiljedang Corporation

Inventor： KIM, Hyung Joon ,  JANG, Ju No ,  KIM, Kyung Rim ,  LEE, Keun Cheol ,  HWANG, Young Bin ,  HONG, Hyeong Pyo

IPC: C12N1/21 ,  C12N15/54 ,  C12P13/22

CPC classification number: C12P13/227 ,  C12N9/1077 ,  C12Y204/02018 ,  Y02P20/52

Abstract: The present invention relates to a microorganism of the genus Escherichia having enhanced L-tryptophan productivity, which has been modified to express yeast anthranilate phosphoribosyltransferase in order to be able to produce L-tryptophan at high concentration, and to a method for producing L-tryptophan, comprising a step of culturing the microorganism. The microorganism of the genus Escherichia can produce L-tryptophan, and thus can be advantageously used in the pharmaceutical industry and the feed industry, particularly for animal feed.

Abstract translation: 本发明涉及具有增强的L-色氨酸生产力的埃希氏菌属微生物，其已被修饰以表达酵母邻氨基苯甲酸磷酸核糖基转移酶以便能够以高浓度生产L-色氨酸，并且涉及生产L-色氨酸的方法 包括培养微生物的步骤。 埃希氏菌属微生物可产生L-色氨酸，因此可有利地用于制药工业和饲料工业，特别是用于动物饲料。

公开(公告)号：EP2801611B1

公开(公告)日：2020-04-01

申请号：EP13733718.4

申请日：2013-01-07

Applicant: CJ Cheiljedang Corporation

Inventor： CHEONG, Ki Yong ,  LEE, Seok Myung ,  HWANG, Young Bin ,  LEE, Keun Cheol ,  LEE, Kwang Ho

IPC: C12N1/21 ,  C12P13/22 ,  C12N15/70

公开(公告)号：EP3296400A1

公开(公告)日：2018-03-21

申请号：EP16792967.8

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： LEE, Seok Myung ,  LEE, Baek Seok ,  KIM, Kyungrim ,  LEE, Kwang Ho ,  LEE, Keun Cheol ,  HONG, Hyeongpyo

IPC: C12N15/70 ,  C12P13/14

CPC classification number: C12P13/227 ,  C12N1/20 ,  C12N15/70 ,  C12P13/14

Abstract: The present invention relates to a microorganism of the genus Escherichia in which L-tryptophan productivity is improved by inactivating phosphatase activity. Further, the present invention relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.

Abstract translation: 本发明涉及埃希氏菌属微生物，其中通过失活磷酸酶活性来提高L-色氨酸生产力。 此外，本发明涉及使用埃希氏菌属微生物生产L-色氨酸的方法。

公开(公告)号：EP3159401A1

公开(公告)日：2017-04-26

申请号：EP15811391.0

申请日：2015-06-23

Applicant: CJ Cheiljedang Corporation

Inventor： CHEONG, Ki Yong ,  KIM, Kyung Rim ,  LEE, Seok Myung ,  LEE, Kwang Ho ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12N1/21 ,  C12N15/52 ,  C12P13/22

CPC classification number: C12P13/227 ,  C12N9/88 ,  C12N15/52 ,  C12P13/22 ,  C12Y401/02014 ,  C12Y402/01012

Abstract: The present application relates to a microorganism of the genus Escherichia producing L-tryptophan and, more specifically, to a microorganism of the genus Escherichia with improved activity of producing L-tryptophan by weakening or inactivating the activity of endogenous 6-phosphogluconate dehydratase and 2-keto-3-deoxy-6-phosphogluconate aldolase.
Additionally, the present application relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.

Abstract translation: 本申请涉及到属微生物大肠杆菌生产L-色氨酸，更具体地说，埃希氏杆菌属的具有改进的产生L-色氨酸通过弱化或失活内源性6-磷酸葡糖酸脱水和2-的活性的酶活性的微生物 酮-3-脱氧-6-磷酸葡糖酸醛缩酶。 此外，本申请涉及一种用于制造使用埃希氏菌属的微生物的L-色氨酸的方法。

公开(公告)号：EP3147351B1

公开(公告)日：2019-08-28

申请号：EP15795904.0

申请日：2015-04-14

Applicant: CJ Cheiljedang Corporation

Inventor： JANG, Juno ,  PARK, Hye Min ,  LEE, Kwang Ho ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12P13/08 ,  C12P13/22

公开(公告)号：EP3119874B1

公开(公告)日：2019-05-08

申请号：EP15764058.2

申请日：2015-03-17

Applicant: CJ Cheiljedang Corporation

Inventor： KOH, Eun Sung ,  KWON, Su Yon ,  LEE, Kwang Ho ,  LEE, Ji Sun ,  JANG, Juno ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12N1/21 ,  C12N15/70 ,  C12P13/04

公开(公告)号：EP3336191A1

公开(公告)日：2018-06-20

申请号：EP16792968.6

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： PARK, Hye Min ,  LEE, Baek Seok ,  LEE, Seok Myung ,  KIM, Kyungrim ,  LEE, Kwang Ho ,  CHEONG, Ki Yong ,  LEE, Keun Cheol ,  HONG, Hyeongpyo

IPC: C12N15/70 ,  C12P13/14

CPC classification number: C12P13/227 ,  C12N9/16 ,  C12N15/71 ,  C12Y301/03

Abstract: The present disclosure relates to a microorganism of the genus Escherichia producing more L-tryptophan by inactivating the activity of phosphatase.
Additionally, the present disclosure relates to a method for producing L-tryptophan using the microorganism of the genus Escherichia.