公开(公告)号：US20240180843A1

公开(公告)日：2024-06-06

申请号：US18285814

申请日：2022-04-27

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Ruhani Singh ,  Daniel Layton ,  Cara Doherty

IPC: A61K9/51 ,  A61K39/00 ,  A61K39/12 ,  A61K47/46 ,  C12N7/00

CPC classification number: A61K9/5146 ,  A61K9/5192 ,  A61K39/12 ,  A61K47/46 ,  C12N7/00 ,  A61K2039/55505 ,  A61K2039/55555

Abstract: The present application relates to metal-organic framework (MOF) encapsulation or viral vaccines and vectors. The present application discloses methods for stabilizing viral vaccines and vectors and provides MOF encapsulated viral vaccines and vectors with improved stability.

公开(公告)号：US20240209397A1

公开(公告)日：2024-06-27

申请号：US18287604

申请日：2022-05-17

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Ruhani Singh ,  Daniel Layton ,  Cara Doherty ,  Xavier Mulet ,  Benjamin Muir

IPC: C12N15/88 ,  A61K47/02 ,  A61K47/24 ,  A61K47/54 ,  A61K47/69 ,  A61K48/00

CPC classification number: C12N15/88 ,  A61K47/02 ,  A61K47/24 ,  A61K47/543 ,  A61K47/6911 ,  A61K48/0041

Abstract: The present application relates to metal-organic framework (MOF) encapsulation of lipid-nucleic acid formulations. The present application discloses methods for stabilizing lipid-nucleic acid formulations and provides MOF encapsulated lipid-nucleic acid formulations with improved stability.