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公开(公告)号:WO1996040642A1
公开(公告)日:1996-12-19
申请号:PCT/US1996009373
申请日:1996-06-07
Applicant: DADE CHEMISTRY SYSTEMS INC.
Inventor: DADE CHEMISTRY SYSTEMS INC. , WANG, Chengrong
IPC: C07D223/22
CPC classification number: G01N33/532 , C07D223/22 , C07D223/32 , G01N33/9473 , G01N33/9486 , Y10S435/969 , Y10S435/97 , Y10S435/975 , Y10S436/823 , Y10S530/806 , Y10T436/171538
Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having general formula (1). The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has general structure (2), where X is C=O, CH2 or SO2; Y is C=O, CH2, SO2; R is an alkyl and P is a protein or a hapten.
Abstract translation: 本发明提供了具有通式(1)的适用于与聚合物颗粒试剂共价连接的新型卡马西平酰肼化合物。 本发明还提供了一种新颖的卡马西平酸化合物,适用于与用于生产卡马西平免疫原的蛋白质相连。 本发明的卡马西平抗原具有通式(2),其中X为C = O,CH 2或SO 2; Y为C = O,CH 2,SO 2; R是烷基,P是蛋白质或半抗原。
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公开(公告)号:EP0775116A1
公开(公告)日:1997-05-28
申请号:EP96921347.0
申请日:1996-06-07
Applicant: Dade Chemistry Systems Inc.
Inventor: WANG, Chengrong
CPC classification number: G01N33/532 , C07D223/22 , C07D223/32 , G01N33/9473 , G01N33/9486 , Y10S435/969 , Y10S435/97 , Y10S435/975 , Y10S436/823 , Y10S530/806 , Y10T436/171538
Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having general formula (1). The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has general structure (2), where X is C=O, CH2 or SO2; Y is C=O, CH2, SO2; R is an alkyl and P is a protein or a hapten.
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