公开(公告)号：EP1484104A4

公开(公告)日：2008-03-12

申请号：EP03743029

申请日：2003-02-26

Applicant: DAICEL CHEM

Inventor： NAKAJIMA HIDEHIKO ,  HARANO YOSHIYUKI ,  YAMADA MANABU

IPC: B01J3/02 ,  B01J3/00 ,  B01J4/00 ,  B01J4/02 ,  B01J8/22 ,  B01J10/00 ,  B01J19/00 ,  C07C51/12 ,  C07C53/08

CPC classification number: B01J19/0006 ,  B01J4/02 ,  B01J10/002 ,  B01J2219/00006 ,  B01J2219/00065 ,  B01J2219/00162 ,  B01J2219/00164 ,  B01J2219/002 ,  B01J2219/00207 ,  B01J2219/00216 ,  B01J2219/0022 ,  B01J2219/00231 ,  B01J2219/0024 ,  C07C51/12 ,  Y02P20/142 ,  C07C53/08

Abstract: A method for controlling the feed of a gaseous reaction component, wherein an alcohol is continuously fed to a pressurized reaction system, carbon monoxide is pressurized by a compressor (8) on a primary feed line (22) and is continuously fed to the reaction system through a secondary feed line (23) at a standard flow rate (F), a surplus of carbon dioxide in the reaction system is allowed to join the flow in the primary feed line (22) through a branched circulation line (24) for reaction, wherein the standard flow rate (F) is the total sun of a standard consumption flow (Fcs) resulting from the reaction and an excess flow (F1) over a variable consumption flow ( ΔFcv)(F = Fcs + F1, F1 > ΔFcv), and wherein based on the variation of the pressure in the gas phase of the reaction system, the flow rate in the circulation line (24) is controlled to the flow Fr = F1 - ΔFcv and the feed flow rate in the primary feed line (22) is controlled to the flow Fsu = Fcs + ΔFcv, to thereby offset the feed of carbon dioxide against the variation in the consumption in the reaction system. The method allows the suppression of the discharge of a gaseous reaction component in a liquid phase pressurized reaction system (a carbonylation reaction system or the like) and thus the effective use of the component.

公开(公告)号：AU2003220831A1

公开(公告)日：2003-09-09

申请号：AU2003220831

申请日：2003-02-26

Applicant: DAICEL CHEM

Inventor： YAMADA MANABU ,  NAKAJIMA HIDEHIKO ,  HARANO YOSHIYUKI

IPC: B01J3/02 ,  B01J3/00 ,  B01J4/00 ,  B01J4/02 ,  B01J8/22 ,  B01J10/00 ,  B01J19/00 ,  C07C51/12 ,  C07C53/08

Abstract: A method comprises continuously supplying an alcohol to a pressurized reaction system, pressurizing carbon monoxide with a compressor 8 attached to a first feed line 22, for continuously supplying carbon monoxide to the reaction system via a second feed line 23 with a reference flow rate F, and converging excess carbon monoxide in the reaction system in the first feed line via a branched circulation line 24 for allowing to react alcohol with carbon monoxide. The reference flow rate F in the second feed line 23 is a total rate of a reference consumption flow rate Fcs in the reaction and a flow rate F1 in excess rate over a fluctuation consumption flow rate DELTA Fcv in the reaction system (F=Fcs+F1, F1> DELTA Fcv). According to the pressure fluctuation of the gaseous phase in the reaction system, the flow rate in the circulation line 24 is controlled to a flow rate Fr=F1- DELTA Fcv and the feed flow rate in the first feed line 22 is controlled to a flow rate Fsu=Fcs+ DELTA Fcv, for compensating a consumption rate variation in the reaction system with the feed flow rate of carbon monoxide. This ensures discharge inhibition of the gaseous reactant in a liquid phase pressurized reaction system (such as carbonylation reaction system) and effective utilization of the reactant for the reaction.

公开(公告)号：MY140979A

公开(公告)日：2010-02-12

申请号：MYPI20031720

申请日：2003-05-07

Applicant: DAICEL CHEM

Inventor： NAKAJIMA HIDEHIKO ,  HARANO YOSHIYUKI ,  YAMADA MANABU

IPC: C07C51/12

Abstract: A METHOD COMPRISES CONTINUOUSLY SUPPLYING AN ALCOHOL TO A PRESSURIZED REACTION SYSTEM, PRESSURIZING CARBON MONOXIDE WITH A COMPRESSOR 8 ATTACHED TO A FIRST FEED LINE 22, FOR CONTINUOUSLY SUPPLYING CARBON MONOXIDE TO THE REACTION SYSTEM VIA A SECOND FEED LINE 23 WITH A REFERENCE FLOW RATE F, AND CONVERGING EXCESS CARBON MONOXIDE IN THE REACTION SYSTEM IN THE FIRST FEED LINE VIA A BRANCHED CIRCULATION LINE 24 FOR ALLOWING TO REACT ALCOHOL WITH CARBON MONOXIDE. THE REFERENCE FLOW RATE F IN THE SECOND FEED LINE 23 IS A TOTAL RATE OF A REFERENCE CONSUMPTION FLOW RATE FCS IN THE REACTION AND A FLOW RATE F1 IN EXCESS RATE OVER A FLUCTUATION CONSUMPTION FLOW RATE ( )FCV IN THE REACTION SYSTEM (F=FCS+F1, F1> ( )FCV). ACCORDING TO THE PRESSURE FLUCTUATION OF THE GASEOUS PHASE IN THE REACTION SYSTEM, THE FLOW RATE IN THE CIRCULATION LINE 24 IS CONTROLLED TO A FLOW RATE FR=F1-( )FCV AND THE FEED FLOW RATE IN THE FIRST FEED LINE 22 IS CONTROLLED TO A FLOW RATE FSU=FCS+ ( )FCV, FOR COMPENSATING A CONSUMPTION RATE VARIATION IN THE REACTION SYSTEM WITH THE FEED FLOW RATE OF CARBON MONOXIDE. THIS ENSURES DISCHARGE INHIBITION OF THE GASEOUS REACTANT IN A LIQUID PHASE PRESSURIZED REACTION SYSTEM (SUCH AS CARBONYLATION REACTION SYSTEM) AND EFFECTIVE UTILIZATION THE REACTANT FOR THE REACTION.

公开(公告)号：JPH11349670A

公开(公告)日：1999-12-21

申请号：JP17817698

申请日：1998-06-10

Applicant: DAICEL CHEM

Inventor： IIYAMA HISASHI ,  SATO TAKASHI ,  YAMADA MANABU ,  UENO TAKASHI

IPC: C07D313/04 ,  C08G63/08 ,  C08G63/78

Abstract: PROBLEM TO BE SOLVED: To provide a process for efficiently conducting the continuous production of a high molecular weight lactone polymer with improved coloring properties or the like which is allowed to have a uniform molecular weight in a reaction apparatus. SOLUTION: Cyclohexanone and an aldehyde are oxidized together or cyclohexanone is oxidized with a peracid to obtain ε-caprolactone and a carboxylic acid which are then added with a group IVa, group Va, group VIa, group VIIa, group VIII group Ib or group IIb element and/or a compound thereof and subjected to distillation to recover ε-caprolactone. The resulting ε- caprolactone alone or together with at least one member selected from the group consisting of another lactone, a bimolecular cyclic ester and a polymer having a hydroxyl group and/or an ester bond as the reaction feedstock is continuously supplied to a tower type continuous reaction apparatus (A) comprising at least one tower type reactor to effect ring-opening polymerization.

公开(公告)号：JPH0374362A

公开(公告)日：1991-03-28

申请号：JP20838889

申请日：1989-08-11

Applicant: DAICEL CHEM

Inventor： TSUJI YASUO ,  YAMADA MANABU

IPC: C07C319/16 ,  C07C323/60

Abstract: PURPOSE:To obtain the title compound in a high yield capable of readily controlling reaction temperature scarcely causing polymerization reaction under table conditions by blending an unsaturated nitrile used as a raw material with water and reacting the unsaturated nitrile kept in suspension state with hydrogen sulfide in the presence of an alkali catalyst. CONSTITUTION:An unsaturated nitrile such as acrylonitrile expressed by the formula (R1 and R2 are H or 1-3C alkyl; n is 0-3) is blended with water 0.5-10 times by vol. the unsaturated nitrile and the unsaturated nitrile kept in suspension state is reacted with hydrogen sulfide in the presence of an alkali catalyst such as NaOH of 1-10mol% based on the compound expressed by the formula under ordinary pressure to 30kg pressure at 10-70 deg.C, preferably 30-50 deg.C and the resultant reaction liquid divided into two layers consisting of upper and lower layers is separated using a separating funnel and the aimed compound contained in each layer is separated by a high performance liquid chromatography and the chromatographed both layers are put together to provide the aimed compound in a high yield of >=95%.

公开(公告)号：JPH10195186A

公开(公告)日：1998-07-28

申请号：JP33355997

申请日：1997-11-18

Applicant: DAICEL CHEM

Inventor： IIYAMA HISASHI ,  SATO TAKASHI ,  YAMADA MANABU

IPC: C08G63/08 ,  C08G63/78 ,  C08G63/88

Abstract: PROBLEM TO BE SOLVED: To obtain a high-quality polyester polymer continuously without encountering many difficulties resulting from an increase in the viscosity of the reaction mixture by using a tower-type continuous reactor in the production of a high-molecular-weight polyester polymer by ring opening polymerization. SOLUTION: A polymerization material comprising at least one lactone is fused in an inert gas atmosphere, continuously fed into a tower-type continuous reactor and polymerized through ring opening to continuously produce a polyester polymer. If required for the purpose of e.g. viscosity control, at most 20 pts.wt., per 100 pts.wt. polymerization component, solvent is added, and the reaction is performed. After the polymerization, the residual monomer and/or the solvent are removed from the formed polymer by means of a devolatilizer contiguous to the reactor and recovered. Alternatively, a polymerization material comprising a cyclic ester formed from two molecules of at least one hydroxycarboxylic acid and at least one polymer having hydroxyl groups and/or ester bonds is continuously fed into a tower-type continuous reactor and copolymerized to continuously produced a polyester polymer.

公开(公告)号：JP2003251167A

公开(公告)日：2003-09-09

申请号：JP2002051797

申请日：2002-02-27

Applicant: DAICEL CHEM

Inventor： NAKAJIMA HIDEHIKO ,  HARANO YOSHIYUKI ,  YAMADA MANABU

IPC: B01J3/02 ,  B01J3/00 ,  B01J4/00 ,  B01J4/02 ,  B01J8/22 ,  B01J10/00 ,  B01J19/00 ,  C07C51/12 ,  C07C53/08

Abstract: PROBLEM TO BE SOLVED: To provide a method which enables the control of the discharge of a gas reaction component in a liquid phase pressurized reaction system (a carbonylation reaction system or the like) and can be used effectively in a reaction. SOLUTION: An alcohol is supplied continuously to the pressurized reaction system, and carbon monoxide is pressurized by the compressor 8 of a primary supply line 22 and supplied continuously to the reaction system in a standard flow rate F by a secondary supply line 23, and the excess carbon monoxide of the reaction system is reacted while being jointed to the primary supply line 22 by a branched circulation line 24. The standard flow rate F of the secondary supply line 23 is the sum of a standard consumption flow rate Fcs by the reaction and a flow rate F1 more excessive than a variable consumption flow rate ΔFcv in the reaction system (F=Fcs+F1, F1>ΔFcv). On the basis of the pressure variation of the gas phase of the reaction system, the flow rate of the circulation line 24 is controlled to be Fr=F1-ΔFcv, the supply flow rate of the primary supply line 22 is controlled to be Fsu=Fcs+ΔFcv, and the variation in the consumption quantity of the reaction system is compensated by the quantity of supplied carbon monoxide. COPYRIGHT: (C)2003,JPO

公开(公告)号：JPH03236337A

公开(公告)日：1991-10-22

申请号：JP3189790

申请日：1990-02-13

Applicant: DAICEL CHEM

Inventor： MATSUOKA KAZUYUKI ,  YAMADA MANABU

IPC: B01J31/10 ,  C07B61/00 ,  C07C29/10 ,  C07C35/14

Abstract: PURPOSE:To obtain the title compound by liquid phase reaction between cyclohexene oxide and an excess of water in the presence of a porous strongly acidic cation exchange resin with sulfonic acid group bound to the skeleton consisting of a styrene-divinylbenzene copolymer. CONSTITUTION:The objective compound can be obtained by liquid phase reaction at room temperature to 120 deg.C between cyclohexene oxide and 2-100 molar times of water using as catalyst a porous strongly acidic cation exchange resin >=0.1m /g in internal surface area, >=5% pore volume and 10-50% in crosslinking degree with sulfonic acid group bound to the skeleton consisting of a styrene- divinylbenzene copolymer. It is preferable that the cyclohexene oxide be added to the system according to the reaction rate while agitating the catalyst and water. This catalyst is small in activity degradation and in the amount of the formation of by-products. The present compound is useful as an intermediate for medicines and pesticides.

公开(公告)号：JPH08134133A

公开(公告)日：1996-05-28

申请号：JP26947394

申请日：1994-11-02

Applicant: DAICEL CHEM

Inventor： YAMADA MANABU ,  GOU HIROYUKI

IPC: C08F4/30 ,  C08F4/28 ,  C08F6/06 ,  C08F6/10

Abstract: PURPOSE: To efficiently recover unreacted allyl alcohol by carrying out the azeotropic distillation and separation of water in a low-boiling fraction separated after copolymerizing the allyl alcohol with styrene in the presence of H2 O2 as an initiator using diallyl ether as an entrainer. CONSTITUTION: The azeotropic distillation and separation of water in a low- boiling fraction obtained by separation with an evaporator, etc., after copolymerizing allyl alcohol (A) with styrene (S) in the presence of H2 O2 as an initiator are carried out using diallyl ether (D) as an entrainer to recover the unreacted A. For example, the low-boiling fraction is charged into a recovering column 1-1 and the D is then charged from the column top to perform the azeotropic distillation. The three-component azeotropic distillation of water in the charging liquid with the A and D is carried out to condense the distillate in a condenser 2-2 at the column top. The condensate is collected in a separating tank 3-3 thereunder and the aqueous layer in the separated lower layer of the condensate is taken out of the system. The upper layer containing the D is returned to the column top of the recovering column 1-1 to recover the dehydrated A from the column bottom.

公开(公告)号：JPH02121962A

公开(公告)日：1990-05-09

申请号：JP27265488

申请日：1988-10-28

Applicant: DAICEL CHEM

Inventor： TSUJI YASUO ,  YAMADA MANABU

IPC: B01J27/02 ,  C07B61/00 ,  C07C319/16 ,  C07C323/52

Abstract: PURPOSE:To produce a mercaptocarboxylic acid in a high yield by reaoting an aqueous solution of an alkaline hydrosulfide with an unsaturated nitrile using a sulfur compound as a reaction accelerator, neutralizing and hydrolyzing the resultant reaction mixture. CONSTITUTION:An unsaturated nitrile (e.g., acrylonitrile) of the formula (R1 and R2 are H or 1-3C alkyl; n is 0-3) is added to an aqueous solution of an alkaline hydrosulfide and the resultant mixture is reacted using a sulfur compound such as sulfur or sodium disulfide as a reaction accelerator in an amount of the order of 0.7-5wt.% based on that of the alkaline hydrosulfide. The resultant reaction mixture is neutralized and hydrolyzed, thus obtaining the objective mercaptocarboxylic acid (e.g., beta-mercaptopropionic acid) in a high yield.