公开(公告)号：WO2013190509A3

公开(公告)日：2013-12-27

申请号：PCT/IB2013/055096

申请日：2013-06-21

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： NARIYAM, Sekhar Munaswamy ,  BHALERAO, Dinesh Shivaji ,  DAHANUKAR, Vilas Hareshwar ,  ORUGANTI, Srinivas ,  RAPOLU, Rajesh Kumar ,  KANDAGATLA, Bhaskar ,  IQBAL, Javed ,  KHOBARE, Sandip Ramdas ,  KALLAM, Srinivasa Reddy ,  BANDA, Malavika ,  GARARE, Vikas Sadashiv ,  EDA, Vishnuvardhana vema Reddy

IPC: C07C273/18 ,  C07C275/16 ,  C07D209/52 ,  C07K5/08 ,  A61K31/401 ,  A61P31/00

Abstract: Processes for preparing intermediates of Boceprevir and their use in preparation of Boceprevir or its pharmaceutically acceptable salts are provided.

公开(公告)号：WO2013168126A1

公开(公告)日：2013-11-14

申请号：PCT/IB2013/053785

申请日：2013-05-10

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： IQBAL, Javed ,  ORUGANTI, Srinivas ,  RAPOLU, Rajesh Kumar ,  PEDDY, Vishweshwar ,  BOGE, Rajesham ,  PATHIVADA, Deepika ,  VELAGA, Dharma Jagannadha Rao ,  YARRAGUNTLA, Sesha Reddy ,  BADDAM, Sudhakar Reddy ,  NAREDLA, Anitha ,  DONIPARTHI, Kiran Kumar ,  NADGOUD, Ramesh Kumar ,  PAGADALA, Narasimha Rao ,  UNNIARAN, Syam Kumar ,  RAMAKRISHNAN, Srividya

IPC: C07D405/14 ,  A61K31/404 ,  A61P25/24

CPC classification number: C07D405/12 ,  C07B2200/13 ,  C07D405/14

Abstract: Provided are crystalline and amorphous vilazodone hydrochloride. Further provided are amorphous solid dispersions of vilazodone hydrochloride with pharmaceutically acceptable carries. Also provided is a process for the preparation of form I of vilazodone free base.

Abstract translation: 提供结晶和无定形的维拉唑酮盐酸盐。 还提供了盐酸维拉扎酮与药学上可接受的载体的无定形固体分散体。 还提供了制备维拉唑酮游离碱形式I的方法。