公开(公告)号：WO2013008250A2

公开(公告)日：2013-01-17

申请号：PCT/IN2012/000468

申请日：2012-07-02

Applicant: DR.REDDYS LABORATORIES LIMITED. ,  PEDDY, Vishweshwar ,  BOGE, Rajesham ,  CHIMALA, Venkata Ramana Reddy ,  MUDAPAKA, Vamsi Krishna ,  PATHIVADA, Deepika ,  NALIVELA, Venu ,  KUMAR, Ramya ,  RAMAKRISHNAN, Srividya ,  RANGINENI, Srinivasulu ,  SAMINENI, Laxmi Charan

Inventor： PEDDY, Vishweshwar ,  BOGE, Rajesham ,  CHIMALA, Venkata Ramana Reddy ,  MUDAPAKA, Vamsi Krishna ,  PATHIVADA, Deepika ,  NALIVELA, Venu ,  KUMAR, Ramya ,  RAMAKRISHNAN, Srividya ,  RANGINENI, Srinivasulu ,  SAMINENI, Laxmi Charan

CPC classification number: C07C271/28 ,  A61K31/325

Abstract: Aspects of the present invention relate to crystalline form of retigabine, process for its preparation and processes for preparation of mixture of known retigabine modifications and pharmaceutical composition comprising thereof.

Abstract translation: 本发明的方面涉及瑞替加林的结晶形式，其制备方法以及制备已知的瑞替加滨改性物的混合物的方法以及包含其的药物组合物。

公开(公告)号：WO2013168126A1

公开(公告)日：2013-11-14

申请号：PCT/IB2013/053785

申请日：2013-05-10

Applicant: DR.REDDYS LABORATORIES LIMITED

Inventor： IQBAL, Javed ,  ORUGANTI, Srinivas ,  RAPOLU, Rajesh Kumar ,  PEDDY, Vishweshwar ,  BOGE, Rajesham ,  PATHIVADA, Deepika ,  VELAGA, Dharma Jagannadha Rao ,  YARRAGUNTLA, Sesha Reddy ,  BADDAM, Sudhakar Reddy ,  NAREDLA, Anitha ,  DONIPARTHI, Kiran Kumar ,  NADGOUD, Ramesh Kumar ,  PAGADALA, Narasimha Rao ,  UNNIARAN, Syam Kumar ,  RAMAKRISHNAN, Srividya

IPC: C07D405/14 ,  A61K31/404 ,  A61P25/24

CPC classification number: C07D405/12 ,  C07B2200/13 ,  C07D405/14

Abstract: Provided are crystalline and amorphous vilazodone hydrochloride. Further provided are amorphous solid dispersions of vilazodone hydrochloride with pharmaceutically acceptable carries. Also provided is a process for the preparation of form I of vilazodone free base.

Abstract translation: 提供结晶和无定形的维拉唑酮盐酸盐。 还提供了盐酸维拉扎酮与药学上可接受的载体的无定形固体分散体。 还提供了制备维拉唑酮游离碱形式I的方法。