公开(公告)号：WO2011106318A2

公开(公告)日：2011-09-01

申请号：PCT/US2011025738

申请日：2011-02-22

Applicant: EDWARDS LIFESCIENCES CORP ,  PHAN LUONG NGOC ,  BACKER STEVEN ,  WILBUR JENNIFER ,  HIGGINS MICHAEL J

Inventor： PHAN LUONG NGOC ,  BACKER STEVEN ,  WILBUR JENNIFER ,  HIGGINS MICHAEL J

IPC: A61B5/145 ,  G06F17/40

CPC classification number: A61B5/002 ,  A61B5/022 ,  A61B2560/045 ,  A61B2562/08

Abstract: A system for sensing a physiological parameter in a human or animal, and storing a processed sensing signal at a sensor with which the sensing was performed. The system includes a physiological sensor adapted to output a sensor signal representative of a sensed physiological parameter, for processing by a remote processor. A microcontroller has memory, and is located locally to the sensor and is fixedly attached to or housed together with the sensor. An authentication algorithm is stored in the memory and the microprocessor is configured to engage in an authentication process to authenticate the sensor when queried by a remote processor. The memory is configured to receive and store data representative of a sensed physiological parameter after data from the sensor has been processed by a remote processor. The microcontroller may be configured to communicate with a remote processor over a single wire by, for example, using a single wire protocol.

Abstract translation: 一种用于感测人或动物中的生理参数并将经处理的感测信号存储在执行感测的传感器的系统。 该系统包括适于输出表示感测的生理参数的传感器信号的生理传感器，用于由远程处理器进行处理。 微控制器具有存储器，并且位于传感器的本地并且固定地附接到传感器或与传感器一起容纳。 认证算法存储在存储器中，并且微处理器被配置为参与认证过程以在远程处理器查询时认证传感器。 存储器被配置为在远程处理器处理来自传感器的数据之后接收和存储表示感测到的生理参数的数据。 微控制器可以被配置为通过例如使用单线协议通过单个线路与远程处理器进行通信。

公开(公告)号：WO2008124346A3

公开(公告)日：2009-03-05

申请号：PCT/US2008058709

申请日：2008-03-28

Applicant: EDWARDS LIFESCIENCES CORP ,  PHAN LUONG NGOC

Inventor： PHAN LUONG NGOC

IPC: A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/14865 ,  A61B2562/182

Abstract: A continuous intravenous analyte monitoring system includes an amperometric biosensor detecting an analyte concentration in the blood, a controller receiving a signal from the biosensor and computing the concentration, and an isolation device isolating the biosensor from EMl. A CPU may be coupled to the controller via the isolation device for continuous output of sensed concentration to a display unit. Isolated circuits may include a temperature sensor transmitting biosensor temperature to the controller for correction of the computed concentration, a multiplexer combining biosensor and temperature sensor signals, and an A/D converter converting multiplexed input to the controller. The biosensor may be a multi-electrode sensor having a working electrode immobilizing an glucose oxidase enzyme to detect blood glucose concentration. The biosensor and temperature sensor may be located in vivo using a catheter for continuous monitoring.

Abstract translation: 连续的静脉内分析物监测系统包括检测血液中的分析物浓度的电流计生物传感器，接收来自生物传感器的信号并计算浓度的控制器以及将生物传感器与EM1隔离的隔离装置。 CPU可以经由隔离装置耦合到控制器，以将感测浓度的连续输出连接到显示单元。 隔离电路可以包括将生物传感器温度传输到控制器以校正计算浓度的温度传感器，组合生物传感器和温度传感器信号的多路复用器，以及将多路复用输入转换成控制器的A / D转换器。 生物传感器可以是具有固定葡萄糖氧化酶以检测血糖浓度的工作电极的多电极传感器。 生物传感器和温度传感器可以使用用于连续监测的导管在体内定位。

公开(公告)号：CA2682043A1

公开(公告)日：2008-10-16

申请号：CA2682043

申请日：2008-03-28

Applicant: EDWARDS LIFESCIENCES CORP

Inventor： PHAN LUONG NGOC

IPC: A61B5/00

Abstract: A continuous intravenous analyte monitoring system includes an amperometr ic biosensor detecting an analyte concentration in the blood, a controller r eceiving a signal from the biosensor and computing the concentration, and an isolation device isolating the biosensor from EMl. A CPU may be coupled to the controller via the isolation device for continuous output of sensed conc entration to a display unit. Isolated circuits may include a temperature sen sor transmitting biosensor temperature to the controller for correction of t he computed concentration, a multiplexer combining biosensor and temperature sensor signals, and an A/D converter converting multiplexed input to the co ntroller. The biosensor may be a multi-electrode sensor having a working ele ctrode immobilizing an glucose oxidase enzyme to detect blood glucose concen tration. The biosensor and temperature sensor may be located in vivo using a catheter for continuous monitoring.

公开(公告)号：CA2703840A1

公开(公告)日：2009-05-07

申请号：CA2703840

申请日：2008-10-31

Applicant: EDWARDS LIFESCIENCES CORP

Inventor： PHAN LUONG NGOC ,  HIGGINS MICHAEL J

IPC: G01N27/327

Abstract: An analyte monitoring system includes a biosensor (10) for detecting an analyte concentration in blood. The monitoring system includes first and second power sources (22, 26), each selectively couplable to the biosensor for providing power to the biosensors. A sensor is associated with the first power source and senses the output thereof. A selector (24) is coupled to both the first and second power sources and the biosensor, such that it may selectively couple an output or outputs of either the first or second power sources to the biosensor. In operation, the first power source (22) is coupled to the biosensor to thereby bias the sensor. If the sensor indicates that the first power source (22) is not providing power to the biosensor, the selector (24) decouples the first power source from the biosensor and couples the second power (26) source to the biosensor to thereby maintain the biosensor in a biased state.

公开(公告)号：CA2688442A1

公开(公告)日：2009-05-07

申请号：CA2688442

申请日：2008-10-31

Applicant: EDWARDS LIFESCIENCES CORP

Inventor： HIGGINS MICHAEL J ,  PHAN LUONG NGOC

IPC: A61B5/00

Abstract: An analyte monitoring system includes a biosensor for detecting an analyt e concentration in blood. The monitoring system includes a sensor for sensin g whether a tool or other piece of equipment is producing electrical noise t hat may affect operation of the biosensor. If such electrical noise is detec ted, the system isolates the biosensor during the period of detected operati on of the other tool or equipment. In some embodiments, the system measures both signal noise in and temperature of the environment surrounding the bios ensor to determine whether another tool or other piece of equipment is curre ntly in operation. The system may also include an auxiliary power source to maintain the biosensor in a biased state during the period when the biosenso r is placed in isolation.

公开(公告)号：EP2538843A4

公开(公告)日：2013-07-24

申请号：EP11747930

申请日：2011-02-22

Applicant: EDWARDS LIFESCIENCES CORP

Inventor： PHAN LUONG NGOC ,  BACKER STEVEN ,  WILBUR JENNIFER ,  HIGGINS MICHAEL J

IPC: G06F17/40 ,  A61B5/00

CPC classification number: A61B5/002 ,  A61B5/022 ,  A61B2560/045 ,  A61B2562/08

Abstract: A system for sensing a physiological parameter in a human or animal, and storing a processed sensing signal at a sensor with which the sensing was performed. The system includes a physiological sensor adapted to output a sensor signal representative of a sensed physiological parameter, for processing by a remote processor. A microcontroller has memory, and is located locally to the sensor and is fixedly attached to or housed together with the sensor. An authentication algorithm is stored in the memory and the microprocessor is configured to engage in an authentication process to authenticate the sensor when queried by a remote processor. The memory is configured to receive and store data representative of a sensed physiological parameter after data from the sensor has been processed by a remote processor. The microcontroller may be configured to communicate with a remote processor over a single wire by, for example, using a single wire protocol.

Abstract translation: 一种用于感测人或动物中的生理参数并将经处理的感测信号存储在执行感测的传感器的系统。 该系统包括适于输出表示感测的生理参数的传感器信号以供远程处理器处理的生理传感器。 微控制器具有存储器，并且位于传感器的本地，并且固定地连接到传感器或与传感器一起容纳。 认证算法被存储在存储器中，并且微处理器被配置为在由远程处理器查询时参与认证过程以认证传感器。 存储器被配置为在来自传感器的数据已经被远程处理器处理之后接收并存储表示感测到的生理参数的数据。 微控制器可以被配置为通过例如使用单线协议通过单线与远程处理器通信。