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公开(公告)号：WO2018085070A1
公开(公告)日：2018-05-11
申请号：PCT/US2017/057856
申请日：2017-10-23
Applicant: EMD MILLIPORE CORPORATION
Inventor： MORRISSEY, Martin
IPC: B01D35/28
Abstract: Containers for separating microcarriers from a cell culture fluid that offer a greater efficiency of filtration of cell culture fluids containing microcarriers relative to systems described in the art. The container may include a first compartment that may include a sterile collapsible bag, an inlet port providing a fluid path into the first compartment and an outlet port providing a fluid path exiting the first compartment; and a second compartment fluidly connected with the inlet port of the first compartment and including a plurality of independent or discrete microcarrier receiving regions defined by boundary walls which are partially or fully porous and having a porosity sufficient to retain the microcarriers inside the second compartment, while allowing the cell culture fluid to pass through the second compartment into the outlet port of the first compartment, where the cell culture fluid can be collected.
Abstract translation: 用于从细胞培养液分离微载体的容器相对于本领域描述的系统提供了包含微载体的细胞培养液的更高的过滤效率。 该容器可以包括第一隔室和第二隔室，第一隔室可以包括无菌可收缩袋，提供流体路径进入第一隔室的入口和提供离开第一隔室的流体路径的出口; 以及与第一隔室的入口端口流体连通并包括多个独立或离散的微载体接收区域的第二隔室，所述微载体接收区域由部分或完全多孔的边界壁限定并且具有足以将微载体保持在第二隔室内的孔隙率，而 允许细胞培养液通过第二隔室进入第一隔室的出口，在那里可以收集细胞培养液。
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公开(公告)号：WO2014085034A1
公开(公告)日：2014-06-05
申请号：PCT/US2013/068373
申请日：2013-11-05
Applicant: EMD MILLIPORE CORPORATION
Inventor： MORRISSEY, Martin , PEREIRA, Brian
IPC: B01F13/08
CPC classification number: B01F7/00241 , B01F7/162 , B01F7/1635 , B01F13/0827 , B01F13/0872 , B01F15/0085
Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The impeller assembly has a protective hood surrounding at least a portion of the moveable blades or vanes of the impeller assembly and being above at least a portion of the blades or vanes. The hood surrounds the blades or vanes and arcs over the height of the blades or vanes. The hood is shaped in a dome shape or semi-spherical shape that is around and above the impeller blades and acts as a protector for the container surface against the impeller assembly both during shipping and storage as well as when in use, particularly at lower liquid levels.
Abstract translation: 用于流体的一次性容器，例如可变形袋，具有一个或多个入口和一个或多个出口以及容器内的叶轮组件，用于引起包含或添加的一种或多种成分的混合，分散，均化和/或循环 到容器 叶轮组件具有围绕叶轮组件的可移动叶片或叶片的至少一部分并且在叶片或叶片的至少一部分上方的保护罩。 发动机罩围绕叶片或叶片并在叶片或叶片的高度上弧形。 发动机罩形成为圆顶形或半球形，其在叶轮叶片周围和上方，并且在运输和储存期间以及在使用时特别是在较低液体下作为用于容器表面抵靠叶轮组件的保护器 水平。
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公开(公告)号：WO2018026418A1
公开(公告)日：2018-02-08
申请号：PCT/US2017/033907
申请日：2017-05-23
Applicant: EMD MILLIPORE CORPORATION
Inventor： MORRISSEY, Martin
IPC: F16L33/22
Abstract: A clamp device for a barb member having a barbed region for disposing within an end of a flexible tube having an outer surface. The clamp device includes a flexible member including a body having a plurality of finger members compressible between a first resting position and a second clamping position; at least one of the flexible finger members having a radially inwardly extending tooth; the body having a through bore and an outer surface comprising threads; the flexible member being slidable over the barbed region and the outer surface of the flexible tube; a compression member having a body having a through bore and an inner surface including threads; the compression member being slidable over the flexible member; wherein upon threadingly engaging the compression member with the flexible member, the compression member compresses the finger member against the barb member.
Abstract translation: 一种用于倒钩构件的夹紧装置，该倒钩构件具有用于设置在具有外表面的柔性管的端部内的倒刺区域。 所述夹持装置包括柔性构件，所述柔性构件包括具有可压缩在第一静止位置和第二夹持位置之间的多个指状构件的本体; 至少一个柔性指状件具有径向向内延伸的齿; 该主体具有通孔和包括螺纹的外表面; 所述柔性构件可滑过所述柔性管的倒刺区域和外表面; 压缩构件，所述压缩构件具有主体，所述主体具有通孔和包括螺纹的内表面; 压缩构件可在柔性构件上滑动; 其中在将所述压缩构件与所述柔性构件螺纹接合时，所述压缩构件将所述指状构件压靠在所述倒钩构件上。
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公开(公告)号：WO2014085035A2
公开(公告)日：2014-06-05
申请号：PCT/US2013/068375
申请日：2013-11-05
Applicant: EMD MILLIPORE CORPORATION
Inventor： MORRISSEY, Martin , PEREIRA, Brian
IPC: B01F3/12
CPC classification number: B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
Abstract translation: 用于流体的一次性容器，例如可变形袋，具有一个或多个入口和一个或多个出口以及容器内的叶轮组件，用于引起包含或添加的一种或多种成分的混合，分散，均化和/或循环 到容器 容器内可容纳液体的区域是漏斗形的，其允许非常低的液面混合，分配同时混合，以及减少或消除涡流形成。
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公开(公告)号：WO2012150991A3
公开(公告)日：2012-11-08
申请号：PCT/US2012/026858
申请日：2012-02-28
Applicant: EMD MILLIPORE CORPORATION , MORRISSEY, Martin , HARTNETT, Jeff
Inventor： MORRISSEY, Martin , HARTNETT, Jeff
Abstract: The present invention is a device for fluid movement and method of making the same. The device has a core element comprised of a preformed barbed fitting having two or more barbed extensions. Each extension has a central bore connected to the central bores of the other extensions so as to provide fluid communications between them. A tube having a central bore is fitted over the barb of each extension. A molded housing is formed over the fitting and tubes to form the device.
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Patent Agency Ranking
公开(公告)号：WO2021040983A1
公开(公告)日：2021-03-04
申请号：PCT/US2020/045085
申请日：2020-08-06
Applicant: EMD MILLIPORE CORPORATION
Inventor： MORRISSEY, Martin , KING, Conor , BOROZENETS, Philip
Abstract: An apparatus for use with an isolator, including a crown for releasably joining with a beta port of the isolator, wherein the crown includes at least one anchoring support; a spring hook on at least one end of the at least one anchoring support; a needle block including at least one through hole for having a needle positioned therein, wherein the at least one needle is joined with tubing; a yoke; and a biasing element releasably joined with the yoke and the at least one anchoring support; wherein the needle block is releasably joined to the crown.
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公开(公告)号：EP2925428A1
公开(公告)日：2015-10-07
申请号：EP13858562.5
申请日：2013-11-05
Applicant: EMD Millipore Corporation
Inventor： MORRISSEY, Martin , PEREIRA, Brian
IPC: B01F13/08
CPC classification number: B01F7/00241 , B01F7/162 , B01F7/1635 , B01F13/0827 , B01F13/0872 , B01F15/0085
Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The impeller assembly has a protective hood surrounding at least a portion of the moveable blades or vanes of the impeller assembly and being above at least a portion of the blades or vanes. The hood surrounds the blades or vanes and arcs over the height of the blades or vanes. The hood is shaped in a dome shape or semi-spherical shape that is around and above the impeller blades and acts as a protector for the container surface against the impeller assembly both during shipping and storage as well as when in use, particularly at lower liquid levels.
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公开(公告)号：EP3869170A1
公开(公告)日：2021-08-25
申请号：EP21169054.0
申请日：2010-03-10
Applicant: EMD Millipore Corporation
Inventor： DELBOS, Cécile , WEISSENBACH, Jean-Louis , VIGNA, James , MORRISSEY, Martin , REINBIGLER, René
Abstract: A method for determining a physical value of a liquid flowing in a pipe, without contact with said liquid, said method comprising:
- providing a sensor (3) for said physical value;
- providing a connector (2) to insert into said pipe and comprising:
- an internal passage (13) extending between two apertures (11, 12),
- a flexible membrane (6) for a pressure sensor, forming a wall of said internal passage (13);
- fastening said sensor (3) onto said connector (2); and
- determining with said sensor (3) said physical value of said liquid flowing in a pipe;
characterized in that said sensor is a temperature sensor (3) and that said step of fastening said sensor (3) onto said connector (2) is such that the sensitive part of said sensor (3) is turned towards said membrane (6).-
公开(公告)号：EP2925427A2
公开(公告)日：2015-10-07
申请号：EP13858238.2
申请日：2013-11-05
Applicant: EMD Millipore Corporation
Inventor： MORRISSEY, Martin , PEREIRA, Brian
IPC: B01F3/12
CPC classification number: B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号：EP3972789A1
公开(公告)日：2022-03-30
申请号：EP20761006.4
申请日：2020-08-06
Applicant: EMD Millipore Corporation
Inventor： MORRISSEY, Martin , KING, Conor , BOROZENETS, Philip
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