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    METHODS AND DEVICES USED FOR REDUNDANT STERILE FILTRATION
    1.
    发明申请
    METHODS AND DEVICES USED FOR REDUNDANT STERILE FILTRATION 审中-公开
    用于冗余无菌过滤的方法和设备

    公开(公告)号：WO2014088882A2

    公开(公告)日：2014-06-12

    申请号：PCT/US2013/071861

    申请日：2013-11-26

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： PERREAULT, Jeremy ,  FOLEY, Sean ,  RAUTIO, Kevin

    IPC: B01D25/26

    CPC classification number: B01D19/0031 ,  A61L2/0017 ,  B01D61/142 ,  B01D61/18 ,  B01D63/084 ,  B01D2313/16 ,  B01D2313/44 ,  B01D2315/08 ,  B01D2317/025 ,  B01D2317/06 ,  B01D2325/36 ,  B01D2325/38

    Abstract: Redundant filtration system that includes at least one barrier filter as a process filter, the barrier filter having both hydrophilic and hydrophobic paths, allowing both fluid and gas permeability. The need for vents is eliminated, as is an intermediate drain filter. The device also can be dried in series. The filtration system includes a network of conduits and receptacles, the network receiving liquid raw and/or starting material at one end, conducting it through the process stream defined thereby, and producing the desired liquid product at another end. The network is provided with one or more inputs for introducing liquid raw material into the fluid process stream, and one or more output ports for discharging fluid out of the fluid process stream. The network is preferably an essentially closed network, and also, preferably sterile and/or aseptic.

    Abstract translation: 冗余过滤系统，其包括至少一个阻挡过滤器作为过程过滤器，该阻隔过滤器具有亲水和疏水路径，允许流体和气体渗透性。 消除了通风口的需要，中间排水过滤器也是如此。 该装置也可以串联干燥。 过滤系统包括管道和容器的网络，网络在一端接收液体原料和/或起始材料，将其通过由其限定的工艺流进行，并在另一端产生所需的液体产物。 该网络具有用于将液体原料引入流体工艺流中的一个或多个输入，以及用于将流体从流体工艺流中排出的一个或多个输出端口。 网络优选是基本上封闭的网络，并且优选地是无菌和/或无菌的。

    DEVICE FOR BIND AND ELUTE CHROMATOGRAPHY USING MEMBRANES, AND METHOD OF MANUFACTURE
    2.
    发明申请
    DEVICE FOR BIND AND ELUTE CHROMATOGRAPHY USING MEMBRANES, AND METHOD OF MANUFACTURE 审中-公开

    公开(公告)号：WO2020172354A1

    公开(公告)日：2020-08-27

    申请号：PCT/US2020/018947

    申请日：2020-02-20

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： RAUTIO, Kevin ,  FOLEY, Sean ,  HUNT, Stephen G. ,  LEE, Bumchul

    IPC: B01D63/08

    Abstract: Single-use integral chromatography unit having an inlet and an outlet, and comprising one or more plates or pairs of filter plates interposable between a pair of end plates. In certain embodiments, each of the filter plates comprises a polymeric framework with one or more membranes supported therein. The filter plates and end plates may be assembled to form a substantially fixed, substantially water-tight, integral stack. Fluid entering the unit through a common inlet passes the membrane or membranes of each filter plate substantially contemporaneously prior to exiting the unit through a common outlet (cf, "parallel" flow). The assembly is a modular design, as multiple pairs of plates can be stacked in a suitable holder to form a single chromatography unit.

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