公开(公告)号：WO2020264138A1

公开(公告)日：2020-12-30

申请号：PCT/US2020/039585

申请日：2020-06-25

Applicant: EMD MILLIPORE CORPORATION

Inventor： YOSHIOKA, Naohisa

IPC: C12N15/86 ,  C12N9/12 ,  C12N5/071

Abstract: Synthetic, self-replicating RNA vectors comprising sequence encoding at least one immortalization protein, and use of the self-replicating RNA vectors to extend the lifespan of primary cell populations and expand said populations of primary cells.

公开(公告)号：EP3969574A1

公开(公告)日：2022-03-23

申请号：EP20729542.9

申请日：2020-05-13

Applicant: EMD Millipore Corporation

Inventor： YOSHIOKA, Naohisa

IPC: C12N7/04 ,  C12N9/22 ,  C12N15/79

公开(公告)号：EP3990648A1

公开(公告)日：2022-05-04

申请号：EP20742561.2

申请日：2020-06-25

Applicant: EMD Millipore Corporation

Inventor： YOSHIOKA, Naohisa

IPC: C12N15/86 ,  C12N9/12 ,  C12N5/071