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1.发明申请
公开(公告)号：WO2019070502A1
公开(公告)日：2019-04-11
申请号：PCT/US2018/053109
申请日：2018-09-27
Applicant: EMD MILLIPORE CORPORATION
Inventor： PEREIRA, Brian , PROULX, Stephen
Abstract: A testing method that includes the steps of evacuating air from a container to a negative atmospheric pressure, the container being a collapsible, flexible container, and comprising at least two opposing flexible walls, wherein a surface of at least one of the walls internal to the container comprises a plurality of channels or recessed features on said at least one wall and monitoring a mass flow or a state of vacuum so as to determine the integrity of the container. The container can be of any size or conformation, with or without attached fittings.
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2.发明申请DEVICE FOR STORING, TRANSPORTING AND/OR HANDLING A LIQUID AND METHOD OF HANDLING A STERILE OR ASEPTIC LIQUID 审中-公开用于储存，运输和/或处理液体的装置和处理无菌或无菌液体的方法
公开(公告)号：WO2017069839A1
公开(公告)日：2017-04-27
申请号：PCT/US2016/046980
申请日：2016-08-15
Applicant: EMD MILLIPORE CORPORATION
Inventor： PROULX, Stephen , DECOSTE, David
Abstract: A device for storing, transporting and/or handling a liquid or liquids and methods for using the device are described. The device is suitable for use with sterile or aseptic liquids, particularly with large liquid volumes such as 10-1000 liters or more, and avoids the need for bags, bins and carriers commonly used for storing and transporting large volumes of liquids. The device comprises a coiled tubing. The coiled tubing can be loaded onto a spool to support the coiled tubing. The tubing can be filled, sealed, stored and transported in a more robust manner than previously achieved with bags, bins and carriers.
Abstract translation: 描述了用于存储，运输和/或处理液体的装置和使用该装置的方法。 该设备适用于无菌或无菌液体，特别是大容量液体，如10-1000升或更多，并且避免了通常用于储存和运输大量液体的袋子，箱和载体的需要。 该装置包括一个连续油管。 连续油管可以装载到卷轴上以支撑连续油管。 该管可以填充，密封，储存和运输，比以前用袋子，箱子和运输工具实现的方式更加可靠。
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公开(公告)号：WO2016140736A1
公开(公告)日：2016-09-09
申请号：PCT/US2016/013057
申请日：2016-01-12
Applicant: EMD MILLIPORE CORPORATION
Inventor： PROULX, Stephen , PEARSONS, Jeffrey
IPC: G01M3/04
CPC classification number: G01M3/3218 , G01M3/3254
Abstract: A system and method for measuring integrity of flexible containers is disclosed. The system uses a low mass flow transducer to monitor the flow of fluid into the flexible container. Based on this flow rate, the existence of an orifice in the flexible container may be detected. The system also includes a second flow path to the flexible container to allow for faster fill times. Greater flow rates are achieve through the use of a second high mass flow transducer or a calibrated bypass path. These alternate paths allow greater flow rates until the flexible container is determined to be nearly full, at which point all flow passes with the low mass flow transducer.
Abstract translation: 公开了一种用于测量柔性容器的完整性的系统和方法。 该系统使用低质量流量传感器来监测流入柔性容器的流体流动。 基于该流量，可以检测柔性容器中的孔的存在。 该系统还包括到柔性容器的第二流动路径以允许更快的填充时间。 通过使用第二高质量流量传感器或经校准的旁路路径实现更大的流速。 这些替代路径允许更大的流速，直到柔性容器被确定为接近满，在该点，所有流动都与低质量流量传感器一起通过。
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4.发明公开
公开(公告)号：EP3692135A1
公开(公告)日：2020-08-12
申请号：EP18786616.5
申请日：2018-09-27
Applicant: EMD Millipore Corporation
Inventor： PEREIRA, Brian , PROULX, Stephen
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公开(公告)号：EP4246115A3
公开(公告)日：2024-01-03
申请号：EP23189863.6
申请日：2018-09-27
Applicant: EMD Millipore Corporation
Inventor： PEREIRA, Brian , PROULX, Stephen
Abstract: A collapsible, flexible bioprocessing container, the container comprising at least two opposing flexible walls, wherein the surface of the walls internal to the container comprise raised areas, the raised areas are surrounded by a plurality of lowered channels on said walls and the channels being interconnected.
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Patent Agency Ranking
公开(公告)号：EP4246115A2
公开(公告)日：2023-09-20
申请号：EP23189863.6
申请日：2018-09-27
Applicant: EMD Millipore Corporation
Inventor： PEREIRA, Brian , PROULX, Stephen
IPC: G01M3/26
Abstract: A collapsible, flexible bioprocessing container, the container comprising at least two opposing flexible walls, wherein the surface of the walls internal to the container comprise raised areas, the raised areas are surrounded by a plurality of lowered channels on said walls and the channels being interconnected.
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公开(公告)号：EP3950919A1
公开(公告)日：2022-02-09
申请号：EP21192523.5
申请日：2018-09-27
Applicant: EMD Millipore Corporation
Inventor： PEREIRA, Brian , PROULX, Stephen
Abstract: A testing method that includes the steps of evacuating air from a container to a negative atmospheric pressure, the container being a collapsible, flexible container, and comprising at least two opposing flexible walls, wherein a surface of at least one of the walls internal to the container comprises a plurality of channels or recessed features on said at least one wall and monitoring a mass flow or a state of vacuum so as to determine the integrity of the container. The container can be of any size or conformation, with or without attached fittings.
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8.发明公开
公开(公告)号：EP3365245A1
公开(公告)日：2018-08-29
申请号：EP16757427.6
申请日：2016-08-15
Applicant: EMD Millipore Corporation
Inventor： PROULX, Stephen , DECOSTE, David
Abstract: A device for storing, transporting and/or handling a liquid or liquids and methods for using the device are described. The device is suitable for use with sterile or aseptic liquids, particularly with large liquid volumes such as 10-1000 liters or more, and avoids the need for bags, bins and carriers commonly used for storing and transporting large volumes of liquids. The device comprises a coiled tubing. The coiled tubing can be loaded onto a spool to support the coiled tubing. The tubing can be filled, sealed, stored and transported in a more robust manner than previously achieved with bags, bins and carriers.
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公开(公告)号：EP3265770A1
公开(公告)日：2018-01-10
申请号：EP16759230.2
申请日：2016-01-12
Applicant: EMD Millipore Corporation
Inventor： PROULX, Stephen , PEARSONS, Jeffrey
IPC: G01M3/04
CPC classification number: G01M3/3218 , G01M3/3254 , G01M3/34
Abstract: A system and method for measuring integrity of flexible containers is disclosed. The system uses a low mass flow transducer to monitor the flow of fluid into the flexible container. Based on this flow rate, the existence of an orifice in the flexible container may be detected. The system also includes a second flow path to the flexible container to allow for faster fill times. Greater flow rates are achieve through the use of a second high mass flow transducer or a calibrated bypass path. These alternate paths allow greater flow rates until the flexible container is determined to be nearly full, at which point all flow passes with the low mass flow transducer.
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公开(公告)号：EP1525023B1
公开(公告)日：2014-03-12
申请号：EP03771865.7
申请日：2003-07-24
Applicant: EMD Millipore Corporation
Inventor： ALMASIAN, Joseph , BELONGIA, Brett , LENTIE, Frank , MORRISSEY, Martin , NAUSEDA, Curtis , NGUYEN, Chau , PROULX, Stephen , RENGANATH, Naren
CPC classification number: F16L29/007 , A61M39/14 , A61M39/18 , A61M39/22 , F16L2201/44 , G01N1/2035 , G01N2001/205 , G01N2001/2071 , Y10S604/905 , Y10T137/87925
Abstract: A sterile to sterile connection device comprising a connector and one or more coupling devices. The connector has body portion which has two openings sealed from the environment so as to form a sterile environment within the connector. At least one of the openings being sealed from the environment by a sterile barrier plug. The connector also has a port capable movement within the body of the connector to at least an open and a closed position. The coupling device is formed of a body having two openings and a stem having a bore through at least a portion of the stem. The stem is contained within the body and capable of moving at least linearly through the body between a first and second stem position. One of the openings of the stem is sealed from the environment by a sterile barrier plug and the other is sealed to a presterilized component. The coupling device opening containing the sterile barrier plug is attached to either the inlet or outlet of the connector.
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