公开(公告)号：WO2013098568A1

公开(公告)日：2013-07-04

申请号：PCT/HU2012/000003

申请日：2012-01-05

Applicant: FEMTONICS KFT. ,  RÓZSA, Balázs ,  KATONA, Gergely ,  VERESS, Máté ,  MAÁK, Pál ,  SZALAY, Gergely

Inventor： RÓZSA, Balázs ,  KATONA, Gergely ,  VERESS, Máté ,  MAÁK, Pál ,  SZALAY, Gergely

IPC: G02F1/33 ,  G02B21/00 ,  G02B27/00

CPC classification number: G02F1/33 ,  G02B5/04 ,  G02B21/002 ,  G02B21/0036 ,  G02B27/0031 ,  G02B27/30

Abstract: The invention relates to a compensator system adapted to compensate for the angular dispersion of electromagnetic beams deflected by at least one acousto-optic deflector of an optical system, wherein the angular dispersion of each deflected beam is dependent on the deflection angle obtained by the deflecting acoustic frequency of the acousto-optic deflector, characterised in that the compensator system comprises: - a first lens group for spatially separating the deflected beams of different deflection angle and angular dispersion by focusing the beams substantially into the focal plane, - a compensator element having a first surface and a second surface, and being arranged such that the first surface of the compensator element lies substantially in the focal plane of the first lens group, and the first and second surfaces of the compensator element have nominal radiuses R 1 and R 2 that together work as prisms with tilt angles β and prism opening angles α p that vary with the distance from the optical axis so as to compensate for the angular dispersion of the spatially separated deflected beams, - a second lens group arranged so as to substantially parallelise the different wavelength components of each deflected beam exiting the compensator element while maintaining the angular variation of the beams deflected at different acoustic frequencies. The invention further relates to method for compensating for the angular dispersion of electromagnetic beams deflected by at least one acousto-optic deflector of an optical system, wherein the angular dispersion of each deflected beam is dependent on the deflection angle obtained by the deflecting acoustic frequency, characterised by - spatially separating the deflected beams of different deflection angle and angular dispersion by focusing the beams via a first lens group substantially into the focal plane of the first lens group, - compensating for the angular dispersion of the spatially separated deflected beams in accordance with the angular dispersion of the given beam, - substantially parallelising the spectral components of each deflected beam while maintaining the angular variation of the beams deflected at different acoustic frequencies.

Abstract translation: 本发明涉及一种补偿器系统，其适于补偿由光学系统的至少一个声光偏转器偏转的电磁波束的角度色散，其中每个偏转光束的角度色散取决于由偏转声学获得的偏转角 声光偏转器的频率，其特征在于补偿器系统包括： - 第一透镜组，用于通过将光束基本聚焦到焦平面中来将不同偏转角和角度色散的偏转光束空间分离， - 补偿元件，其具有 第一表面和第二表面，并且被布置成使得补偿元件的第一表面基本上位于第一透镜组的焦平面中，并且补偿元件的第一和第二表面具有共同工作的标称半径R1和R2 作为具有倾斜角度β和棱镜开口角度的棱镜随着分布而变化的棱镜 以便补偿空间分离的偏转光束的角度色散; - 第二透镜组，其布置成基本上平行于离开补偿元件的每个偏转光束的不同波长分量，同时保持 不同声频偏转的光束。 本发明还涉及用于补偿由光学系统的至少一个声光偏转器偏转的电磁光束的角度色散的方法，其中每个偏转光束的角度色散取决于由偏转声频率获得的偏转角， 其特征在于 - 通过将所述光束经由第一透镜组基本上聚焦到所述第一透镜组的焦平面中，将所述偏转光束的偏转角和角度色散空间分离， - 补偿空间分离的偏转光束的角度色散， 给定光束的角度色散， - 基本上平行于每个偏转光束的光谱分量，同时保持以不同声频偏转的光束的角度变化。

公开(公告)号：WO2018042214A2

公开(公告)日：2018-03-08

申请号：PCT/HU2017/050035

申请日：2017-08-31

Applicant: FEMTONICS KFT

Inventor： RÓZSA, Balázs ,  KATONA, Gergely ,  MAÁK, Pál ,  VERESS, Máté ,  FEHÉR, András ,  SZALAY, Gergely ,  MÁTYÁS, Péter

IPC: G02B21/00 ,  G02F1/33

Abstract: The invention relates to a method for scanning along a substantially straight line (3D line) lying at an arbitrary direction in a 3D space with a given speed using a 3D laser scanning microscope having a first pair of acousto-optic deflectors deflecting a laser beam in the x-z plane (x axis deflectors) and a second pair of acousto-optic deflectors deflecting the laser beam in the y-z plane (y axis deflectors) for focusing the laser beam in 3D. The invention further relates to a method for scanning a region of interest with a 3D laser scanning microscope having acousto-optic deflectors for focusing a laser beam within a 3D space defined by an optical axis (Z) of the microscope and X, Y axes that are perpendicular to the optical axis and to each other.

Abstract translation: 本发明涉及一种用3D激光扫描显微镜沿3D空间中任意方向的基本上直线（3D线）以给定速度进行扫描的方法，3D显微镜具有第一对声波 -optic偏转器偏转在xz平面中的激光束（x轴的偏转器）和第二对声光偏转器偏转在yz平面中用于聚焦激光束在三维激光束（y轴的偏转器）。 本发明还涉及一种用3D激光扫描显微镜扫描感兴趣区域的方法，所述3D激光扫描显微镜具有声光偏转器，用于将激光束聚焦在由显微镜的光轴（Z）和X，Y轴限定的3D空间内， 垂直于光轴和彼此。

公开(公告)号：WO2018042214A3

公开(公告)日：2018-03-08

申请号：PCT/HU2017/050035

申请日：2017-08-31

Applicant: FEMTONICS KFT

Inventor： RÓZSA, Balázs ,  KATONA, Gergely ,  MAÁK, Pál ,  VERESS, Máté ,  FEHÉR, András ,  SZALAY, Gergely ,  MÁTYÁS, Péter

IPC: G02B21/00 ,  G02F1/33

Abstract: The invention relates to a method for scanning along a substantially straight line (3D line) lying at an arbitrary direction in a 3D space with a given speed using a 3D laser scanning microscope having a first pair of acousto-optic deflectors deflecting a laser beam in the x-z plane (x axis deflectors) and a second pair of acousto-optic deflectors deflecting the laser beam in the y-z plane (y axis deflectors) for focusing the laser beam in 3D. The invention further relates to a method for scanning a region of interest with a 3D laser scanning microscope having acousto-optic deflectors for focusing a laser beam within a 3D space defined by an optical axis (Z) of the microscope and X, Y axes that are perpendicular to the optical axis and to each other.

公开(公告)号：WO2013102771A1

公开(公告)日：2013-07-11

申请号：PCT/HU2012/000001

申请日：2012-01-05

Applicant: FEMTONICS KFT. ,  RÓZSA, Balázs ,  KATONA, Gergely ,  VERESS, Máté ,  MAÁK, Pál ,  SZALAY, Gergely ,  KASZÁS, Attila ,  CHIOVINI, Balász ,  MÁTYÁS, Péter

Inventor： RÓZSA, Balázs ,  KATONA, Gergely ,  VERESS, Máté ,  MAÁK, Pál ,  SZALAY, Gergely ,  KASZÁS, Attila ,  CHIOVINI, Balász ,  MÁTYÁS, Péter

IPC: G02F1/33 ,  G02B21/00 ,  G01N21/64

CPC classification number: G02F1/332 ,  G02B21/004 ,  G02B26/101 ,  G02F1/33 ,  G02F2001/291 ,  G02F2201/16

Abstract: The invention relates to a method for scanning along a continuous scanning trajectory with a scanner system (100) comprising a first pair of acousto-optic deflectors (10) for deflecting a focal spot of an electromagnetic beam generated by a consecutive lens system (200) defining an optical axis (z) in an x-z plane, and a second pair of acousto-optic deflectors (20) for deflecting the focal spot in a y-z plane being substantially perpendicular to the x-z plane, characterised by changing the acoustic frequency sweeps with time continuously in the deflectors (12, 12') of the first pair of deflectors (10) and in the deflectors (22, 22') of the second pair of deflectors (20) so as to cause the focal spot to move continuously along the scanning trajectory.

Abstract translation: 本发明涉及一种用扫描仪系统（100）沿连续扫描轨迹进行扫描的方法，扫描仪系统（100）包括第一对声光偏转器（10），用于偏转连续透镜系统（200）产生的电磁波束的焦点， 在xz平面中限定光轴（z），以及第二对声光偏转器（20），用于偏转基本上垂直于xz平面的yz平面中的焦斑，其特征在于随时间改变声频扫描 连续地在第一对偏转器（10）的偏转器（12,12'）和第二对偏转器（20）的偏转器（22,22'）中，以使焦斑沿着 扫描轨迹。

公开(公告)号：WO2013050798A2

公开(公告)日：2013-04-11

申请号：PCT/HU2012/000100

申请日：2012-10-03

Applicant: FEMTONICS KFT. ,  CSIZMADIA, Imre Gyula ,  MUCSI, Zoltán ,  SZALAY, Gergely ,  KASZÁS, Attila ,  LUKÁCSNÉ HAVELAND, Csilla ,  MAJERCSIK, Orsolya ,  POTOR, Attila ,  KATONA, Gergely ,  RÓZSA, József Balázs ,  GÜNDISCH, Dorina ,  CHIOVINI, Balázs ,  PÁLFI, Dénes

Inventor： CSIZMADIA, Imre Gyula ,  MUCSI, Zoltán ,  SZALAY, Gergely ,  KASZÁS, Attila ,  LUKÁCSNÉ HAVELAND, Csilla ,  MAJERCSIK, Orsolya ,  POTOR, Attila ,  KATONA, Gergely ,  RÓZSA, József Balázs ,  GÜNDISCH, Dorina ,  CHIOVINI, Balázs ,  PÁLFI, Dénes

IPC: C07D209/08

CPC classification number: C12Q1/52 ,  C07D209/08 ,  C07D209/14 ,  C07D209/20 ,  C12Q1/32

Abstract: Use of photochemically cleavable compounds in course of one or multi-photon irradiation experiments.

Abstract translation: 在一次或多光子照射实验过程中使用光化学裂解化合物。

公开(公告)号：WO2022248895A1

公开(公告)日：2022-12-01

申请号：PCT/HU2021/050034

申请日：2021-05-28

Applicant: FEMTONICS KFT. ,  HCEMM NONPROFIT KFT. ,  SEMMELWEIS EGYETEM

Inventor： RÓZSA, J. Balázs ,  KATONA, Gergely ,  MÁTHÉ, Domokos ,  MUCSI, Zoltán ,  KOVÁCS, Ervin ,  SZILÁGYI, Szandra ,  KONTRA, Bence ,  SZALAY, Gergely

IPC: C09B11/06 ,  C09K11/06 ,  G01N33/84

Abstract: Compound of the general formula (I), in which which R1 and R2 represent independently a hydrogen atom, straight-chain or branched, unsubstituted or C1-C10 alkyl or C1-C10 alkoxy group substituted by one or more halogen atoms, substituted or unsubstituted aryl or aralkyl group, with the proviso that at least one of R1 and R2 is not hydrogen, one of R3 and R4 is a hydrogen atom, and the other represents a group of the general formula (II) wherein R5 and R6 represent independently a hydrogen atom, C1-C4 alkyl, C1-C4 alkoxy group, or R5 and R6 together form a -O-CH2-O- group, R7 represents a hydrogen atom, C1-C4 or C1-C4 alkoxy group, and tautomeric forms and salts thereof.

公开(公告)号：WO2021009526A1

公开(公告)日：2021-01-21

申请号：PCT/HU2020/050029

申请日：2020-07-09

Applicant: FEMTONICS KFT.

Inventor： DOBOS, Gergely ,  PINKE, Domonkos Péter ,  DR. TOMPA, Tamás ,  MAÁK, Pál ,  MAROSI, Máté ,  KATONA, Gergely ,  SZALAY, Gergely ,  RÓZSA, Balázs

IPC: A01K29/00 ,  G02B27/01 ,  A01K15/02 ,  A01K1/03

Abstract: The present invention relates to a virtual reality simulator (10) for small laboratory animals (100), in particular rodents, which comprises a head clamping mechanism (20) for securing the laboratory animal (100) and virtual reality glasses (40) with two wings (30), each of the wings (30) having a display (34) and a lens system (36) spaced therefrom and connected together by a light barrier cover (32), and the virtual reality glasses (40) are configured to allow the two wings (30) to align with each of the eyes (101 ) of the laboratory animal (100), respectively. The invention further relates to a method applying such a simulator (10).

公开(公告)号：WO2013050795A1

公开(公告)日：2013-04-11

申请号：PCT/HU2011/000129

申请日：2011-12-20

Applicant: FEMTONICS KFT. ,  CSIZMADIA, Imre Gyula ,  MUCSI, Zoltán ,  SZALAY, Gergely ,  KASZÁS, Attila ,  LUKÁCSNÉ HAVELAND, Csilla ,  MAJERCSIK, Orsolya ,  POTOR, Attila ,  KATONA, Gergely ,  RÓZSA, József Balázs ,  GÜNDISCH, Dorina ,  CHIOVINI, Balázs

Inventor： CSIZMADIA, Imre Gyula ,  MUCSI, Zoltán ,  SZALAY, Gergely ,  KASZÁS, Attila ,  LUKÁCSNÉ HAVELAND, Csilla ,  MAJERCSIK, Orsolya ,  POTOR, Attila ,  KATONA, Gergely ,  RÓZSA, József Balázs ,  GÜNDISCH, Dorina ,  CHIOVINI, Balázs

IPC: C07D209/08

CPC classification number: C12Q1/52 ,  C07D209/08 ,  C07D209/14 ,  C07D209/20 ,  C12Q1/32

Abstract: Use of photochemically cleavable compounds in course of one or multi-photon irradiation experiments. ˙

Abstract translation: 在一次或多光子照射实验过程中使用光化学裂解化合物。 。

公开(公告)号：WO2020035710A1

公开(公告)日：2020-02-20

申请号：PCT/HU2019/050039

申请日：2019-08-14

Applicant: FEMTONICS KFT.

Inventor： KATONA, Gergely ,  FEHÉR, András ,  VERESS, Máté ,  MAÁK, Pál ,  SZALAY, Gergely ,  CHIOVINI, Balázs ,  SZADAI, Zoltán ,  SULCZ-JUDÁK, Linda ,  RÓZSA, Balázs József

IPC: G02F1/11 ,  G02F1/33 ,  G02B21/00

Abstract: The object of the invention relates to a method for scanning with an optical beam (50) using a first acousto-optic deflector (15, 15') having an optical axis along a Z-axis and at least one acousto-optic crystal layer (14), involving directing the optical beam (50) in the first acousto-optic deflector (15, 15'), and deflecting the optical beam (50) along an X-axis perpendicular to the Z-axis by means of the first acousto-optic deflector (15, 15'), during which generating a plurality of acoustic chirp signals (30) in the at least one acousto-optic crystal layer (14) of the acousto-optic deflector (15, 15') by - generating a first acoustic chirp signal (30a) having a duration of τ in the acousto-optic crystal layer (14), then - generating a second acoustic chirp signal (30b) in the acousto-optic crystal layer (14) within a τ period of time counted from the start of the generation of the first acoustic chirp signal (30a).

公开(公告)号：WO2018042214A9

公开(公告)日：2018-03-08

申请号：PCT/HU2017/050035

申请日：2017-08-31

Applicant: FEMTONICS KFT

Inventor： RÓZSA, Balázs ,  KATONA, Gergely ,  MAÁK, Pál ,  VERESS, Máté ,  FEHÉR, András ,  SZALAY, Gergely ,  MÁTYÁS, Péter

IPC: G02B21/00 ,  G02F1/33

Abstract: The invention relates to a method for scanning along a substantially straight line (3D line) lying at an arbitrary direction in a 3D space with a given speed using a 3D laser scanning microscope having a first pair of acousto-optic deflectors deflecting a laser beam in the x-z plane (x axis deflectors) and a second pair of acousto-optic deflectors deflecting the laser beam in the y-z plane (y axis deflectors) for focusing the laser beam in 3D. The invention further relates to a method for scanning a region of interest with a 3D laser scanning microscope having acousto-optic deflectors for focusing a laser beam within a 3D space defined by an optical axis (Z) of the microscope and X, Y axes that are perpendicular to the optical axis and to each other.