公开(公告)号：HK1248739A1

公开(公告)日：2018-10-19

申请号：HK18108653

申请日：2018-07-04

Applicant: FLUIDIGM CANADA INC

Inventor： WINNIK MITCHELL A ,  NITZ MARK ,  BARANOV VLADIMIR ,  LOU XUDONG

IPC: C08F20060101 ,  G01N20060101

公开(公告)号：PT2444804E

公开(公告)日：2015-11-25

申请号：PT07008035

申请日：2007-05-28

Applicant: FLUIDIGM CANADA INC

Inventor： WINNIK MITCHELL A ,  MARK NITZ ,  BARANOV VLADIMIR ,  LOU XUDONG

IPC: G01N33/53 ,  C08F8/42 ,  C08F220/36

公开(公告)号：CA3145861A1

公开(公告)日：2021-02-11

申请号：CA3145861

申请日：2020-08-07

Applicant: FLUIDIGM CANADA INC ,  GOVERNING COUNCIL UNIV TORONTO

Inventor： LIU PENG ,  MAJONIS DANIEL ,  BARANOV VLADIMIR ,  WINNIK MITCHELL A ,  CHO HYUNGJUN

IPC: A61K51/04

Abstract: A new class of mass-tag polymers is provided, which include enriched metal isotopes such as zirconium and hafnium mass tags. The chemistry of these new mass tags are different from that of lanthanide mass tags, and opens up new mass channels that can be used in mass cytometry. These polymers may be used for mass cytometry, therapeutic delivery of a radioactive isotope, or screening of a therapeutic isotope. Aspects include a kit, method of making, and method of using a polymer, isotopic composition, or both. A kit may include a polymer. The polymer may include pendant groups that chelate an enriched isotope, such as zirconium and/or hafnium. The kit may include an isotopic composition comprising an enriched zirconium or hafnium isotope. Polymers may be conjugated to a biologically active material. Aspects may also include making a kit. Aspects include use of a kit, such as for mass cytometry.

公开(公告)号：DK2444804T3

公开(公告)日：2015-11-30

申请号：DK11008035

申请日：2007-05-28

Applicant: FLUIDIGM CANADA INC

Inventor： WINNIK MITCHELL A ,  NITZ MARK ,  BARANOV VLADIMIR ,  LOU XUDONG

IPC: G01N33/53 ,  C08F8/42 ,  C08F220/36

公开(公告)号：CA3112016A1

公开(公告)日：2020-03-19

申请号：CA3112016

申请日：2019-09-09

Applicant: FLUIDIGM CANADA INC ,  GOVERNING COUNCIL UNIV TORONTO

Inventor： CLOSSON TAUNIA ,  BARANOV VLADIMIR ,  WINNIK MITCHELL A

IPC: G01N15/10 ,  G01N33/50

Abstract: This disclosure relates to reagents and their use for elemental imaging mass spectrometry of biological samples.