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公开(公告)号:WO2008043046A3
公开(公告)日:2008-08-07
申请号:PCT/US2007080489
申请日:2007-10-04
Applicant: FLUIDIGM CORP , WANG JING , NASSEF HANY R
Inventor: WANG JING , NASSEF HANY R
CPC classification number: F16K99/0026 , B01L3/502738 , B01L2200/12 , B01L2300/0887 , B01L2400/0605 , B01L2400/0638 , F16K99/0001 , F16K99/0057 , F16K2099/0078 , F16K2099/008
Abstract: A microfluidic check valve and a method of using the check valve In microfluidic devices includes a check valve comprising two stacked chambers that are separated by a pore-containing membrane. The membrane is composed of an elastomeric material and can be configured in normally open or normally closed state. The normally open check valve can be implemented so that the degree of back pressure necessary to close the valve can be set.
Abstract translation: 微流体止回阀和使用止回阀的方法在微流体装置中包括止回阀,其包括由含孔膜隔开的两个堆叠室。 膜由弹性体材料构成,可以配置成常开或常闭状态。 可以实现常开止回阀,使得可以设定关闭阀所需的背压程度。
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公开(公告)号:WO2004000721A3
公开(公告)日:2005-02-03
申请号:PCT/US0319775
申请日:2003-06-23
Applicant: FLUIDIGM CORP , MANGER IAN D , BARCO JOSEPH W , NASSEF HANY R
Inventor: MANGER IAN D , BARCO JOSEPH W , NASSEF HANY R
IPC: B01L3/00 , B81C20060101 , F04B19/00 , F04B43/02 , G01N21/00 , G01N33/53 , G01N33/543 , G01N33/566 , G01N37/00
CPC classification number: B81B3/00 , B01L3/5025 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0861 , B01L2300/088 , B01L2300/0887 , B01L2400/0415 , B01L2400/0481 , B01L2400/0655 , F04B19/006 , F04B43/02 , F16K99/0001 , F16K99/0003 , F16K99/0026 , F16K99/0036 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , F16K2099/0084 , G01N33/5304 , G01N33/54366 , Y10T436/2575
Abstract: The present invention provides microfluidic devices comprising elastomeric components and solid substrate component for attaching ligands and methods for conducting a variety of assays and high throughput screening. The elastomeric components comprise a plurality of first and second flow channels forming a plurality of intersecting areas, further capable of forming looped flow channels, and in fluid communication with the solid substrate surface, a plurality of control channels, a plurality of first and second control valves, and a plurality of loop forming control valves.
Abstract translation: 本发明提供了包含弹性体组分和用于附着配体的固体底物组分和用于进行各种测定和高通量筛选的方法的微流体装置。 弹性体部件包括形成多个相交区域的多个第一和第二流动通道,其还能够形成环形流动通道,并且与固体基板表面流体连通,多个控制通道,多个第一和第二控制 阀和多个回路成形控制阀。
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公开(公告)号:AU2003277853A8
公开(公告)日:2004-01-06
申请号:AU2003277853
申请日:2003-06-23
Applicant: FLUIDIGM CORP
Inventor: BARCO JOSEPH W , NASSEF HANY R , MANGER IAN D
IPC: B01L3/00 , B81C20060101 , F04B19/00 , F04B43/02 , G01N21/00 , G01N33/53 , G01N33/543 , G01N33/566 , G01N37/00
Abstract: A microfluidic device includes a plurality of first flow channels and a plurality of second flow channels, each such second flow channel intersecting multiple of the first flow channels to define intersecting volumes and a plurality of looped flow channels that each include segments of the flow channels between the intersecting volumes to define a closed loop. The microfluidic device also includes a plurality of control valves each such control valve having a control channel and a deformable segment disposed to restrict flow through a respective one of the first and second flow channels in response to an actuation force applied to the control channel to deflect the deformable segment. The microfluidic device further includes a pump operatively disposed to regulate flow through one of the looped flow channels to regulate flow by the recirculating pump.
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公开(公告)号:AU2003277853A1
公开(公告)日:2004-01-06
申请号:AU2003277853
申请日:2003-06-23
Applicant: FLUIDIGM CORP
Inventor: MANGER IAN D , BARCO JOSEPH W , NASSEF HANY R
IPC: B01L3/00 , B81C20060101 , F04B19/00 , F04B43/02 , G01N21/00 , G01N33/53 , G01N33/543 , G01N33/566 , G01N37/00
Abstract: A microfluidic device includes a plurality of first flow channels and a plurality of second flow channels, each such second flow channel intersecting multiple of the first flow channels to define intersecting volumes and a plurality of looped flow channels that each include segments of the flow channels between the intersecting volumes to define a closed loop. The microfluidic device also includes a plurality of control valves each such control valve having a control channel and a deformable segment disposed to restrict flow through a respective one of the first and second flow channels in response to an actuation force applied to the control channel to deflect the deformable segment. The microfluidic device further includes a pump operatively disposed to regulate flow through one of the looped flow channels to regulate flow by the recirculating pump.
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公开(公告)号:EP2074341A4
公开(公告)日:2013-04-10
申请号:EP07843872
申请日:2007-10-04
Applicant: FLUIDIGM CORP
Inventor: WANG JING , NASSEF HANY R
CPC classification number: F16K99/0026 , B01L3/502738 , B01L2200/12 , B01L2300/0887 , B01L2400/0605 , B01L2400/0638 , F16K99/0001 , F16K99/0057 , F16K2099/0078 , F16K2099/008
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