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公开(公告)号:KR20200138750A
公开(公告)日:2020-12-10
申请号:KR20207028795
申请日:2019-03-06
Inventor: HACKENBERGER CHRISTIAN , BAUMANN ALICE LEONIE , KASPER MARC ANDRE , BYRNE STEPHEN , HELMA SMETS JONAS , LEONHARDT HEINRICH , STOSCHECK TINA , GERLACH MARCUS , SCHUMACHER DOMINIK
Abstract: 신규한접합체및 그의제조방법이개시된다. 알켄- 또는알킨-포스포노티올레이트및 -포스포네이트를제조하는방법은화학식 (I)의화합물을화학식 (II)의티올-함유분자와반응시켜화학식 (III)의화합물을생성하는단계를포함한다: JPEGpct00657.jpg3731JPEGpct00658.jpg1728JPEGpct00659.jpg4653 상기식에서, JPEGpct00660.jpg49는아미노산, 펩티드, 단백질, 항체, 뉴클레오티드, 올리고뉴클레오티드, 당류, 다당류, 중합체, 임의적으로치환된 C1-C8-알킬, 임의적으로치환된페닐, 또는임의적으로치환된방향족의 5 또는 6원헤테로사이클릭시스템을나타낸다.
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2.
公开(公告)号:AU2019232602B2
公开(公告)日:2025-03-27
申请号:AU2019232602
申请日:2019-03-06
Inventor: HACKENBERGER CHRISTIAN , BAUMANN ALICE LEONIE , KASPER MARC-ANDRÉ , BYRNE STEPHEN , HELMA-SMETS JONAS , LEONHARDT HEINRICH , STOSCHECK TINA , GERLACH MARCUS , SCHUMACHER DOMINIK
Abstract: Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene-or alkyne-phosohonothiolates and -phosphonates comprises the step of: reacting a compound of formula (I) with a thiol-containing molecule of formula (II) wherein represents an amino acid, a peptide, a protein, an antibody, a nucleotide, an oligonucleotide, a saccharide, a polysaccharide, a polymer, an optionally substituted C
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3.
公开(公告)号:AU2019232602A1
公开(公告)日:2020-09-17
申请号:AU2019232602
申请日:2019-03-06
Inventor: HACKENBERGER CHRISTIAN , BAUMANN ALICE LEONIE , KASPER MARC-ANDRÉ , BYRNE STEPHEN , HELMA-SMETS JONAS , LEONHARDT HEINRICH , STOSCHECK TINA , GERLACH MARCUS , SCHUMACHER DOMINIK
Abstract: Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene-or alkyne-phosohonothiolates and -phosphonates comprises the step of: reacting a compound of formula (I) with a thiol-containing molecule of formula (II) wherein represents an amino acid, a peptide, a protein, an antibody, a nucleotide, an oligonucleotide, a saccharide, a polysaccharide, a polymer, an optionally substituted C
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4.
公开(公告)号:CA3092286A1
公开(公告)日:2019-09-12
申请号:CA3092286
申请日:2019-03-06
Inventor: HACKENBERGER CHRISTIAN , BAUMANN ALICE LEONIE , KASPER MARC-ANDRE , BYRNE STEPHEN , HELMA-SMETS JONAS , LEONHARDT HEINRICH , STOSCHECK TINA , GERLACH MARCUS , SCHUMACHER DOMINIK
Abstract: Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene-or alkyne-phosohonothiolates and -phosphonates comprises the step of: reacting a compound of formula (I) with a thiol-containing molecule of formula (II) wherein represents an amino acid, a peptide, a protein, an antibody, a nucleotide, an oligonucleotide, a saccharide, a polysaccharide, a polymer, an optionally substituted C1-C8-alkyl, an optionally substituted phenyl, or an optionally substituted aromatic 5-or 6- membered heterocyclic system; resulting in a compound of formula (III)..
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5.
公开(公告)号:SG11202008186RA
公开(公告)日:2020-09-29
申请号:SG11202008186R
申请日:2019-03-06
Inventor: HACKENBERGER CHRISTIAN , BAUMANN ALICE LEONIE , KASPER MARC-ANDRÉ , BYRNE STEPHEN , HELMA-SMETS JONAS , LEONHARDT HEINRICH , STOSCHECK TINA , GERLACH MARCUS , SCHUMACHER DOMINIK
Abstract: Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene- or alkyne-phosohonothiolates and -phosphonates comprises the step of: reacting a compound of formula (I) with a thiol-containing molecule of formula (II) wherein represents an amino acid, a peptide, a protein, an antibody, a nucleotide, an oligonucleotide, a saccharide, a polysaccharide, a polymer, an optionally substituted C1-C8-alkyl, an optionally substituted phenyl, or an optionally substituted aromatic 5- or 6-membered heterocyclic system; resulting in a compound of formula (III).
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