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    HYDRODYNAMIC FOCUSING DEVICE
    1.
    发明申请
    HYDRODYNAMIC FOCUSING DEVICE 审中-公开

    公开(公告)号：WO2021144635A1

    公开(公告)日：2021-07-22

    申请号：PCT/IB2020/061305

    申请日：2020-12-01

    Applicant: FOSS ANALYTICAL A/S

    Inventor： BISGAARD, Christer Zoffmann ,  BRASK, Anders ,  TEMBOURY, Miguel Carro

    IPC: G01N15/14 ,  G01N15/10 ,  G01N15/1404 ,  G01N15/1436 ,  G01N2015/1006 ,  G01N2015/1413

    Abstract: A hydrodynamic focusing device, preferably realized as a microfluidic device, comprises a first flow channel (4); a smaller second flow channel (8); an envelopment region (12) connected in-line between the first (4) and the second (8) flow channels; and a chimney (14) comprising a body (16) and a sample fluid inlet (18), which extends from a, preferably sloped, wall (20) delimiting the envelopment region (12) and into the envelopment region (12). The body (16) and the sample fluid inlet (18) are each formed with an elongate, preferably teardrop-shaped, profile having a leading edge (28) facing the first flow channel (4) and opposing long edges (30a, 30b) relatively tapered towards a trailing edge (32).

    DETERMINATION OF ANALYTES IN A SAMPLE MATRIX BY SOLVENT EXTRACTION
    2.
    发明申请
    DETERMINATION OF ANALYTES IN A SAMPLE MATRIX BY SOLVENT EXTRACTION 审中-公开
    通过溶剂萃取法确定样品基质中的分析物

    公开(公告)号：WO2016063104A1

    公开(公告)日：2016-04-28

    申请号：PCT/IB2014/065461

    申请日：2014-10-20

    Applicant: FOSS ANALYTICAL A/S

    Inventor： BISGAARD, Christer Zoffmann ,  DAHL, Malin ,  HOLM, Claus

    IPC: A23L1/015 ,  A23B9/00 ,  G01N1/40

    CPC classification number: G01N1/40 ,  A23L5/23 ,  B01D11/02 ,  B01D11/0203 ,  G01N1/34 ,  G01N1/4055 ,  G01N15/1012 ,  G01N15/1459 ,  G01N30/60 ,  G01N33/543 ,  G01N33/569 ,  G01N2001/2893 ,  G01N2001/4061 ,  G01N2015/1006 ,  G01N2015/1018 ,  G01N2030/009 ,  G01N2030/062

    Abstract: Determination of Analytes in a Sample Matrix by Solvent Extraction A method for the assay of one or more analytes in a sample matrix comprising the steps of: performing analyte extraction on the sample matrix, said analyte extraction comprising combining the sample matrix with a solvent for an extraction period which is less than that required for reaching equilibrium; and separating the analyte containing solvent from the sample matrix; next measuring a level of analyte present in the separated solvent; and then applying in a computer a calibration by which is established a mathematical relationship between levels of analyte extracted from each of a plurality of reference samples by means of the process employed above in the extraction for the sample matrix and a reference value of the levels of analyte for each reference sample to thereby derive a measure of the level of analyte in the sample matrix. Specifically a method to determine the amount of mycotoxins in cereal grain, especially OTA (ochratoxin A) and DON (deoxynivalenol) by mixing with a solvent comprising water alcohol mixture, with 20-40% ethanol by volume.

    Abstract translation: 通过溶剂萃取测定样品基质中的分析物一种用于测定样品基质中一种或多种分析物的方法，包括以下步骤：在样品基质上进行分析物提取，所述分析物提取包括将样品基质与溶剂组合，用于 提取时间小于达到平衡所需的时间; 并从样品基质中分离含有分析物的溶剂; 接下来测量分离的溶剂中存在的分析物的水平; 然后在计算机中应用校准，通过该校准建立了从多个参考样本中的每一个提取的分析物的水平之间的数学关系，借助于上述在样本矩阵的提取中使用的过程以及水平的参考值 分析物，从而得到样品基质中分析物水平的量度。 具体地说，一种通过与包含水醇混合物的溶剂与体积为20-40％乙醇的混合来测定谷粒中尤其是OTA（赭曲霉毒素A）和DON（脱氧雪腐镰刀菌烯醇）的霉菌毒素的量的方法。

    DETERMINATION OF ANALYTES IN A SAMPLE MATRIX BY SOLVENT EXTRACTION
    3.
    发明公开
    DETERMINATION OF ANALYTES IN A SAMPLE MATRIX BY SOLVENT EXTRACTION 审中-公开
    溶剂萃取法测定样品基质中的分析物

    公开(公告)号：EP3209145A1

    公开(公告)日：2017-08-30

    申请号：EP14805666.6

    申请日：2014-10-20

    Applicant: FOSS Analytical A/S

    Inventor： BISGAARD, Christer Zoffmann ,  DAHL, Malin ,  HOLM, Claus

    IPC: A23L5/20 ,  A23B9/00 ,  G01N1/40

    CPC classification number: G01N1/40 ,  A23L5/23 ,  B01D11/02 ,  B01D11/0203 ,  G01N1/34 ,  G01N1/4055 ,  G01N15/1012 ,  G01N15/1459 ,  G01N30/60 ,  G01N33/543 ,  G01N33/569 ,  G01N2001/2893 ,  G01N2001/4061 ,  G01N2015/1006 ,  G01N2015/1018 ,  G01N2030/009 ,  G01N2030/062

    Abstract: Determination of Analytes in a Sample Matrix by Solvent Extraction A method for the assay of one or more analytes in a sample matrix comprising the steps of: performing analyte extraction on the sample matrix, said analyte extraction comprising combining the sample matrix with a solvent for an extraction period which is less than that required for reaching equilibrium; and separating the analyte containing solvent from the sample matrix; next measuring a level of analyte present in the separated solvent; and then applying in a computer a calibration by which is established a mathematical relationship between levels of analyte extracted from each of a plurality of reference samples by means of the process employed above in the extraction for the sample matrix and a reference value of the levels of analyte for each reference sample to thereby derive a measure of the level of analyte in the sample matrix. Specifically a method to determine the amount of mycotoxins in cereal grain, especially OTA (ochratoxin A) and DON (deoxynivalenol) by mixing with a solvent comprising water alcohol mixture, with 20-40% ethanol by volume.

    Abstract translation: 通过溶剂提取测定样品基质中的分析物用于测定样品基质中的一种或多种分析物的方法包括以下步骤：在样品基质上进行分析物提取，所述分析物提取包括将样品基质与溶剂 提取时间小于达到平衡所需的时间; 并从样品基质中分离含分析物的溶剂; 接下来测量分离的溶剂中存在的分析物的水平; 然后在计算机中应用校准，借助于上面在采样矩阵的提取中所采用的过程以及参考值的参考值建立从多个参考样本中的每一个提取的分析物的水平之间的数学关系 分析每个参考样品的分析物，从而导出样品基质中分析物水平的量度。 特别是通过与包含水醇混合物的溶剂和20-40％体积乙醇混合来测定谷物中特别是OTA（赭曲霉毒素A）和DON（脱氧雪腐镰刀菌烯醇）中霉菌毒素的量的方法。

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