公开(公告)号：WO2003056320A3

公开(公告)日：2003-07-10

申请号：PCT/EP2002/014761

申请日：2002-12-24

Applicant: FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS (F.O.R.T.H) ,  FOTAKIS, Costas ,  THIREOS, George ,  ZERGIOTI, Ioanna ,  KAFETZOPOULOS, Dimitris

Inventor： FOTAKIS, Costas ,  THIREOS, George ,  ZERGIOTI, Ioanna ,  KAFETZOPOULOS, Dimitris

IPC: B01J19/00

Abstract: A method and an apparatus for microfabricating precision patterns of biopolymers onto solid substrates by means of laser transfer are disclosed. The method involves the use of ultrafast laser pulses for transferring target biopolymer material, dimensioned according to the focal spot of the laser, from one surface of a transparent support onto the opposite positioned surface of receiving substrate. Repeating the transfer process at different target and substrate positions results in the production of extended patterns such as arrays of features or localized coatings. The apparatus is designed to produce the patters of biopolymers on solid substrates in an automated fashion. The method and the apparatus are of particular utility in producing devices for biological and biochemical assay systems such as biosensors and microarrays.

公开(公告)号：WO2003056320A2

公开(公告)日：2003-07-10

申请号：PCT/EP2002/014761

申请日：2002-12-24

Applicant: FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS (F.O.R.T.H) ,  FOTAKIS, Costas ,  THIREOS, George ,  ZERGIOTI, Ioanna ,  KAFETZOPOULOS, Dimitris

Inventor： FOTAKIS, Costas ,  THIREOS, George ,  ZERGIOTI, Ioanna ,  KAFETZOPOULOS, Dimitris

IPC: G01N27/327

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00441 ,  B01J2219/00527 ,  B01J2219/00529 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00727 ,  B01J2219/0074 ,  B41J2/04515 ,  B41J2/04573 ,  B41J2/04581 ,  B41J2/04588 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14

Abstract: A method and an apparatus for microfabricating precision patterns of biopolymers onto solid substrates by means of laser transfer are disclosed. The method involves the use of ultrafast laser pulses for transferring target biopolymer material, dimensioned according to the focal spot of the laser, from one surface of a transparent support onto the opposite positioned surface of receiving substrate. Repeating the transfer process at different target and substrate positions results in the production of extended patterns such as arrays of features or localized coatings. The apparatus is designed to produce the patters of biopolymers on solid substrates in an automated fashion. The method and the apparatus are of particular utility in producing devices for biological and biochemical assay systems such as biosensors and microarrays.

Abstract translation: 公开了通过激光转移将生物聚合物的精密图案微调到固体基底上的方法和装置。 该方法包括使用超快激光脉冲将目标生物聚合物材料（根据激光的焦斑尺寸设置）从透明支撑体的一个表面转移到接收基底的相对定位的表面上。 在不同目标和基板位置重复转移过程导致生产扩展图案，如特征阵列或局部涂层。 该设备被设计成以自动化方式在固体基底上产生生物聚合物的图案。 该方法和装置在生物和生物化学测定系统如生物传感器和微阵列的生产装置中特别有用。

公开(公告)号：EP1461146A2

公开(公告)日：2004-09-29

申请号：EP02791868.9

申请日：2002-12-24

Applicant: FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS

Inventor： FOTAKIS, Costas ,  THIREOS, George ,  ZERGIOTI, Ioanna ,  KAFETZOPOULOS, Dimitris;

IPC: B01J19/00

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00441 ,  B01J2219/00527 ,  B01J2219/00529 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00727 ,  B01J2219/0074 ,  B41J2/04515 ,  B41J2/04573 ,  B41J2/04581 ,  B41J2/04588 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14

Abstract: A method and an apparatus for microfabricating precision patterns of biopolymers onto solid substrates by means of laser transfer are disclosed. The method involves the use of ultrafast laser pulses for transferring target biopolymer material, dimensioned according to the focal spot of the laser, from one surface of a transparent support onto the opposite positioned surface of receiving substrate. Repeating the transfer process at different target and substrate positions results in the production of extended patterns such as arrays of features or localized coatings. The apparatus is designed to produce the patters of biopolymers on solid substrates in an automated fashion. The method and the apparatus are of particular utility in producing devices for biological and biochemical assay systems such as biosensors and microarrays.