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    METHODS AND DEVICES FOR DYNAMIC FILTRATION OF PHARMACEUTICAL PRODUCTS
    1.
    发明申请
    METHODS AND DEVICES FOR DYNAMIC FILTRATION OF PHARMACEUTICAL PRODUCTS 审中-公开
    用于动态过滤药物产品的方法和装置

    公开(公告)号：WO2009002794A3

    公开(公告)日：2009-03-05

    申请号：PCT/US2008067440

    申请日：2008-06-19

    Applicant: GEN ELECTRIC ,  LEACH ANDREW MICHAEL ,  MILLER PETER ,  TELFEYAN ERIC JOHN ,  WHITT DAVID BRANDON

    Inventor： LEACH ANDREW MICHAEL ,  MILLER PETER ,  TELFEYAN ERIC JOHN ,  WHITT DAVID BRANDON

    IPC: B01D69/14 ,  B01J47/00

    CPC classification number: A61M5/165 ,  B01D15/00 ,  B01D15/08 ,  B01D15/322 ,  B01D15/327 ,  B01J20/103 ,  B01J20/26 ,  B01J20/3242

    Abstract: A device for dynamic filtration of a pharmaceutical product is provided. The device includes a resin configured to selectively retain one or more components from a mixture having the pharmaceutical product, where the resin is configured to be activated by a medium of the mixture. The device further includes at least one positioning material disposed adjacent to the resin, where the positioning material is configured to provide mechanical support to the resin to at least partially retain the resin in position. In certain embodiments, the device does not require conditioning immediately prior to filtration.

    Abstract translation: 提供了用于药物动力过滤的装置。 该装置包括被配置为从具有药物产品的混合物中选择性地保持一种或多种组分的树脂，其中树脂被配置为由混合物的介质活化。 该装置还包括邻近树脂设置的至少一个定位材料，其中定位材料构造成为树脂提供机械支撑以至少部分地将树脂保持在适当位置。 在某些实施方案中，该装置在过滤之前不需要立即进行调节。

    SENSOR SYSTEM AND METHODS FOR IMPROVED QUANTITATION OF ENVIRONMENTAL PARAMETERS
    3.
    发明申请
    SENSOR SYSTEM AND METHODS FOR IMPROVED QUANTITATION OF ENVIRONMENTAL PARAMETERS 审中-公开
    传感器系统和改进环境参数定量的方法

    公开(公告)号：WO2005052598A3

    公开(公告)日：2008-01-03

    申请号：PCT/US2004039213

    申请日：2004-11-23

    Applicant: GEN ELECTRIC ,  POTYRAILO RADISLAV ALEXANDROVI ,  MORRIS WILLIAM GUY ,  BOYETTE SCOTT MARTELL ,  WISNUDEL MARC BRIAN ,  LEACH ANDREW MICHAEL ,  STANLEY MARY LYNN

    Inventor： POTYRAILO RADISLAV ALEXANDROVI ,  MORRIS WILLIAM GUY ,  BOYETTE SCOTT MARTELL ,  WISNUDEL MARC BRIAN ,  LEACH ANDREW MICHAEL ,  STANLEY MARY LYNN

    IPC: G01N35/00 ,  B01L3/00 ,  G01N21/59

    CPC classification number: G01N21/5907 ,  B01J2219/00536 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01L3/502715 ,  B01L3/545 ,  B01L2300/024 ,  B01L2300/0806 ,  G01N35/00069

    Abstract: Systems and methods employing optical disk drives (202) for quantitative analysis of chemical and biochemical parameters are provided. A system (200) includes an optical disk (204) having at least one sensor region (205), a light source (208) for directing light onto the at least one sensor region, an optical detector (210) for detecting interacted light transmitted from the sensor region, the interacted transmitted light being indicative of a concentration of an environmental parameter disposed on the sensor region (205), and an analog-to-digital converter (220) for quantifying a measurable property of the interacted transmitted light. A method for preparing an optical disk (300) with a plurality of sensor spots (306) is provided. A system (1900) includes a robotic arm (1904) for transmitting the disk through a variety of stations that include dipping the disk into a source of a compound, removing excess amounts of the source, optically scanning the disk, and discarding the disk. A system (200) includes control software for directing the light source (208) and optical detector (210) to specified positions of the disk (204) during disk rotation, and for processing the sensor response data to display a map of the sensor material response, and to improve precision of the measured signal.

    Abstract translation: 提供了使用光盘驱动器（202）进行化学和生化参数定量分析的系统和方法。 一种系统（200）包括具有至少一个传感器区域（205），用于将光引导到至少一个传感器区域上的光源（208）的光盘（204），用于检测所传输的相互作用的光 来自传感器区域的相互作用的透射光指示设置在传感器区域（205）上的环境参数的浓度，以及用于量化相互作用的透射光的可测量性质的模数转换器（220）。 提供了一种用于制备具有多个传感器点（306）的光盘（300）的方法。 系统（1900）包括机器人手臂（1904），用于通过包括将盘浸入到化合物源中的各种站传输盘，去除多余的源，光学扫描盘并丢弃盘。 一种系统（200）包括用于在光盘旋转期间将光源（208）和光学检测器（210）引导到盘（204）的指定位置的控制软件，并且用于处理传感器响应数据以显示传感器材料的图 响应，并提高测量信号的精度。

    APPARATUS AND METHOD FOR FULLY AUTOMATED CLOSED SYSTEM OPTICAL MEASUREMENT OF VOLUME
    4.
    发明申请
    APPARATUS AND METHOD FOR FULLY AUTOMATED CLOSED SYSTEM OPTICAL MEASUREMENT OF VOLUME 审中-公开
    全自动封闭系统的光学测量装置和方法

    公开(公告)号：WO2008137642A3

    公开(公告)日：2009-01-08

    申请号：PCT/US2008062366

    申请日：2008-05-02

    Applicant: GEN ELECTRIC ,  MILLER PETER ,  LEACH ANDREW MICHAEL

    Inventor： MILLER PETER ,  LEACH ANDREW MICHAEL

    IPC: G01N21/01

    CPC classification number: G01N21/31 ,  G01F23/292 ,  G01N21/0303

    Abstract: The present invention provides an apparatus and method for a noninvasive optical determination of the volume of a fluid in a compartment within a closed system comprising a compartment wherein a fluid resides which is permeable to at least one wavelength of light, a light source and light detecting device configured to obtain spectral data for a fluid for at least one wavelength, a processor adapted to determine the volume of the fluid by correlating the spectral data for a fluid at a known path length with the spectral data for the fluid at an unknown path length and wherein the processor is further configured to control the release of the substance from the compartment to its end use.

    Abstract translation: 本发明提供了一种用于非封闭光学确定封闭系统内的隔室中的流体体积的装置和方法，所述封闭系统包括隔室，其中流体存在，所述隔室可透过至少一个波长的光，光源和光检测 被配置为获得用于至少一个波长的流体的光谱数据的处理器，适于通过将已知路径长度处的流体的光谱数据与未知路径长度的流体的光谱数据相关联来确定流体的体积的处理器 并且其中所述处理器还被配置为控制所述物质从所述隔室到其最终用途的释放。

    SENSOR SYSTEM AND METHODS FOR IMPROVED QUANTITATION OF ENVIRONMENTAL PARAMETERS
    6.
    发明申请
    SENSOR SYSTEM AND METHODS FOR IMPROVED QUANTITATION OF ENVIRONMENTAL PARAMETERS 审中-公开
    传感器系统和改进环境参数量化的方法

    公开(公告)号：WO2005052598A8

    公开(公告)日：2006-06-15

    申请号：PCT/US2004039213

    申请日：2004-11-23

    Applicant: GEN ELECTRIC ,  POTYRAILO RADISLAV ALEXANDROVI ,  MORRIS WILLIAM GUY ,  BOYETTE SCOTT MARTELL ,  WISNUDEL MARC BRIAN ,  LEACH ANDREW MICHAEL ,  STANLEY MARY LYNN

    Inventor： POTYRAILO RADISLAV ALEXANDROVI ,  MORRIS WILLIAM GUY ,  BOYETTE SCOTT MARTELL ,  WISNUDEL MARC BRIAN ,  LEACH ANDREW MICHAEL ,  STANLEY MARY LYNN

    IPC: G01N35/00 ,  B01L3/00 ,  G01N21/59

    CPC classification number: G01N21/5907 ,  B01J2219/00536 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01L3/502715 ,  B01L3/545 ,  B01L2300/024 ,  B01L2300/0806 ,  G01N35/00069

    Abstract: Systems and methods employing optical disk drives (202) for quantitative analysis of chemical and biochemical parameters are provided. A system (200) includes an optical disk (204) having at least one sensor region (205), a light source (208) for directing light onto the at least one sensor region, an optical detector (210) for detecting interacted light transmitted from the sensor region, the interacted transmitted light being indicative of a concentration of an environmental parameter disposed on the sensor region (205), and an analog-to-digital converter (220) for quantifying a measurable property of the interacted transmitted light. A method for preparing an optical disk (300) with a plurality of sensor spots (306) is provided. A system (1900) includes a robotic arm (1904) for transmitting the disk through a variety of stations that include dipping the disk into a source of a compound, removing excess amounts of the source, optically scanning the disk, and discarding the disk. A system (200) includes control software for directing the light source (208) and optical detector (210) to specified positions of the disk (204) during disk rotation, and for processing the sensor response data to display a map of the sensor material response, and to improve precision of the measured signal.

    Abstract translation: 提供了使用光盘驱动器（202）进行化学和生化参数定量分析的系统和方法。 一种系统（200）包括具有至少一个传感器区域（205），用于将光引导至至少一个传感器区域的光源（208）的光盘（204），用于检测相互传输的光的光检测器 来自传感器区域的相互作用的透射光指示设置在传感器区域（205）上的环境参数的浓度，以及用于量化相互作用的透射光的可测量性质的模数转换器（220）。 提供了一种用于制备具有多个传感器点（306）的光盘（300）的方法。 系统（1900）包括用于通过包括将盘浸入到化合物的源中的多个站来传送盘的机器人手臂（1904），去除多余的源，光学扫描盘和丢弃盘。 一种系统（200）包括用于在光盘旋转期间将光源（208）和光学检测器（210）引导到盘（204）的指定位置的控制软件，并且用于处理传感器响应数据以显示传感器材料的图 响应，并提高测量信号的精度。

    Sistema de trajetória de fluido, sistema polarizador e método para manufaturar
    10.
    发明专利
    Sistema de trajetória de fluido, sistema polarizador e método para manufaturar 未知

    公开(公告)号：BR102013000152A2

    公开(公告)日：2015-05-12

    申请号：BR102013000152

    申请日：2013-01-03

    Applicant: GEN ELECTRIC

    Inventor： URBAHN JOHN ARTHUR ,  LEACH ANDREW MICHAEL ,  WHITT DAVID BRANDON ,  DIETRICH DAVID KEY ,  TELFEYAN ERIC JOHN ,  LARSEN JAN HENRIK ARDENKJAER ,  MILLER PETER ,  STAUTNER ERNST WOLFGANG

    IPC: G01R33/28 ,  G01R33/30

    Abstract: Sistema de trajetória de fuido, sistema polarizador e método para manufaturar. Trata-se de um sistema de trajetória de fluido que inclui um frasco que contém um produto farmacêutico no mesmo, uma tajetória de fluido de dissolução também é incluida no sistema de trajetória de fluido, sendo que a trajetória de fluido de dissolução possui uma extremidade de saída em comunicação fluida com o frasco e uma extremidade de entrada anexa a um recipiente de pressão que contém um meio de dissolução. Uma trajetória de fluido de entrega é também incluida no sistema que possui uma primeira extremidade anexa de forma hermétrica ao frasco para transportar do mesmo uma mistura de produto farmacêuticos dissolvido e meio de dissolução e uma segunda extremidade conectada a um recipiente de recepção para receber a mistura. Uma válvula de trajetória de fluido de dissolução é posicionada entre o recipiente de pressão e a trajétória de fluido de dissolução para controlar o fluxo do meio de dissolução, e uma válvula de trajetória de fluido de entrega é também incluída no sistema de trajetória de fluido para controlar fluxo da mistura da trajetória de fluido de entrega para o recipiente de recepção.

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