公开(公告)号：WO1992005822A1

公开(公告)日：1992-04-16

申请号：PCT/US1991007078

申请日：1991-09-26

Applicant: GLAXO INC.

Inventor： GLAXO INC. ,  CASPER, Robert, A. ,  McCARTNEY, Michael, L. ,  JOCHEM, Warren, J. ,  PARR, Alan, F.

IPC: A61M11/00

CPC classification number: A61B5/42 ,  A61B5/073 ,  A61B10/0045 ,  A61B2010/0061 ,  A61F2210/0023

Abstract: A medical capsule device (10) for releasing and/or collecting a substance at a defined location in the gastrointestinal tract. The device has a capsule body (12) defining one or more apertures in the circumferential wall thereof and a sleeve valve rotatably positioned therein having one or more corresponding apertures in the circumferential wall thereof. The sleeve valve comprises a coil and electrically connected heatable resistor which are operatively associated with an actuator member (16J, 16I) formed of a shape memory alloy responsive to heat and which will move from a non-heated first shape to a heated second shape. Actuator stop means (20) are provided in the capsule body for being engaged by the actuator member during movement from the non-heated first shape to the heated second shape so that the actuator member movement will serve to rotate the sleeve valve to either an open or closed position.