公开(公告)号：US20150313847A1

公开(公告)日：2015-11-05

申请号：US14650440

申请日：2012-12-07

Applicant: GUMLINK A/S

Inventor： Tony Dalentoft ,  Niels Ravn Schmidt

IPC: A61K9/20 ,  A61K31/722 ,  A61K9/48 ,  A23G4/20

CPC classification number: A61K9/2095 ,  A23G3/0019 ,  A23G3/004 ,  A23G3/008 ,  A23G3/54 ,  A23G4/04 ,  A23G4/043 ,  A23G4/046 ,  A23G4/06 ,  A23G4/08 ,  A23G4/20 ,  A61K9/4808 ,  A61K9/4825 ,  A61K9/4833 ,  A61K31/722 ,  B30B11/085 ,  B30B11/34

Abstract: The present invention pertains to a method of producing a compressed tablet in a rotary tablet press. The method including the steps of adding a first powdered portion of tablet base material into a punch die of a rotary tablet press, pressing the first tablet base material by means of an upper and a lower punch to obtain a first pressed material, inserting an object at the upper face of the first pressed material and fixing the object in a central cavity of the first pressed material, adding a second powdered portion of tablet base material into the punch die of the rotary tablet press, and pressing the first and second tablet base material around the object to enclose the object from the surface of the tablet. The object is based on a material different from the first and/or the second powdered portion of tablet base material.

Abstract translation: 本发明涉及一种在旋转式压片机中制造压缩片剂的方法。 该方法包括以下步骤：将片剂基材的第一粉末部分添加到旋转压片机的冲模中，通过上冲头和下冲头挤压第一片基材以获得第一压制材料，将物体插入 在第一压制材料的上表面上并将物体固定在第一压制材料的中心腔中，将片状基材的第二粉末部分添加到旋转式压片机的冲模中，并且将第一和第二片剂基底 围绕物体的材料以从片剂的表面封闭物体。 该目的是基于与片剂基材的第一和/或第二粉末部分不同的材料。