公开(公告)号：EP3150989A4

公开(公告)日：2018-01-31

申请号：EP15798894

申请日：2015-05-15

Applicant: HAMAMATSU PHOTONICS KK

Inventor： YAMAMOTO SATOSHI ,  FUKUMITSU KENSHI

IPC: G01N21/64 ,  A61B5/1455 ,  B23K26/53 ,  F21S2/00 ,  F21Y101/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/25 ,  G01N21/27 ,  G01N21/49 ,  G02B6/00

CPC classification number: G02B6/0035 ,  A61B5/1455 ,  B23K26/0057 ,  B23K26/032 ,  B23K26/53 ,  F21S2/00 ,  G01N21/01 ,  G01N21/03 ,  G01N21/253 ,  G01N21/27 ,  G01N21/47 ,  G01N21/49 ,  G01N21/55 ,  G01N21/64 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N33/4833 ,  G01N2201/06113 ,  G01N2201/068 ,  G02B6/00

Abstract: An optical plate is an optical plate for irradiating a target with light, and includes a light input surface for inputting the light, a light output surface for outputting the light, a back surface opposite to the light output surface, and a light diffusion portion formed at least inside the optical plate by converging laser light, for diffusing the light. The light input surface is a surface between the light output surface and the back surface, and the light input from the light input surface is diffused in the light diffusion portion and output from the light output surface.

公开(公告)号：EP2955505A4

公开(公告)日：2016-11-02

申请号：EP14748553

申请日：2014-02-05

Applicant: HAMAMATSU PHOTONICS KK

Inventor： IWAI HIDENAO ,  KATAOKA TAKUJI ,  YAMAMOTO SATOSHI ,  SUGIYAMA NORIKAZU ,  YAMAUCHI TOYOHIKO ,  GOTO KENTARO

IPC: G01N21/47 ,  G01B11/00 ,  G01N21/17 ,  G01N21/49 ,  G01P3/36

CPC classification number: G01N33/4833 ,  G01B11/00 ,  G01N21/47 ,  G01N21/49 ,  G01N2021/4707 ,  G01N2021/479

Abstract: An aggregated cell evaluation apparatus 1 includes a laser light source 10, a speckle image acquisition unit 20, an SC calculation unit 30, an evaluation unit 40, and a memory unit 50. The speckle image acquisition unit 20 acquires a two-dimensional speckle image by forward scattered light generated in aggregated cells 90 by irradiation of the aggregated cells 90 with laser light output from the laser light source 10. The SC calculation unit 30 calculates a speckle contrast value K n of a speckle image In at each time t n , determines a maximum value K max among the speckle contrast values K 1 to K N , and normalizes the speckle contrast value K n at each time t n by the maximum value K max to obtain a normalized speckle contrast value K n '. The evaluation unit 40 evaluates motion of the aggregated cells 90, based on the normalized speckle contrast value K n ' at each time t n . This realizes a method and an apparatus capable of readily evaluating the motion of aggregated cells.

公开(公告)号：JP2014153154A

公开(公告)日：2014-08-25

申请号：JP2013022234

申请日：2013-02-07

Applicant: Hamamatsu Photonics Kk ,  浜松ホトニクス株式会社

Inventor： IWAI HIDENAO ,  KATAOKA TAKUJI ,  YAMAMOTO SATOSHI ,  SUGIYAMA NORIKAZU ,  YAMAUCHI TOYOHIKO ,  GOTO KENTARO

IPC: G01N21/47 ,  G01B11/00 ,  G01N21/17 ,  G01P3/36

CPC classification number: G01N33/4833 ,  G01B11/00 ,  G01N21/47 ,  G01N21/49 ,  G01N2021/4707 ,  G01N2021/479

Abstract: PROBLEM TO BE SOLVED: To provide a method and device capable of easily evaluating motion of aggregated cells.SOLUTION: An aggregated cells evaluation device 1 includes a laser beam source 10, a speckle image acquisition part 20, an SC calculation part 30, an evaluation part 40, and a storage part 50. The speckle image acquisition part 20 acquires a two-dimensional speckle image caused by forward scattered light generated in aggregated cells 90 by irradiation of the aggregated cells 90 with laser beam output from the laser beam source 10. The SC calculation part 30 calculates a speckle contrast value Kof a speckle image Iat each time tto obtain a maximum value Kamong speckle contrast values Kto Kand normalizes the speckle contrast value Kat each time tby the maximum value Kto obtain a normalized speckle contrast value K'. The evaluation part 40 evaluates motion of the aggregated cells 90 on the basis of the normalized speckle contrast value K' at each time t.

Abstract translation: 要解决的问题：提供能够容易地评估聚集电池的运动的方法和装置。解决方案：聚集电池评估装置1包括激光束源10，散斑图像获取部20，SC计算部30，评价 部分40和存储部分50.斑点图像获取部分20通过从激光束源10输出的激光束照射聚集单元90，获得由聚集单元90中产生的正向散射光引起的二维散斑图像。 SC计算部30计算每次得到最大值Kamong散斑对比度值Kto K的斑点图像Iat的散斑对比度值K，并且每次以最大值K为标准化散斑对比度值即可得到归一化斑点对比度值K'。 评价部40基于每个时刻t的归一化斑点对比度值K'来评价聚集单元90的运动。

公开(公告)号：JP2019020125A

公开(公告)日：2019-02-07

申请号：JP2017135427

申请日：2017-07-11

Applicant: HAMAMATSU PHOTONICS KK

Inventor： SUGIYAMA NORIKAZU ,  MATSUBARA MASANORI ,  YAMAMOTO SATOSHI

IPC: G01N21/64 ,  G02B21/06 ,  G02B21/36

Abstract: 【課題】メンブレンフィルタを通って移動した試料と移動しなかった試料との双方を観察できる試料観察装置及び試料観察方法を提供する。【解決手段】試料観察装置1は、メンブレンフィルタを透過する面状光の照射によって発生した観察光を撮像して蛍光画像データを出力する撮像部13と、第1の試料保持空間に対応する第1の領域と第2の試料保持空間に対応する第2の領域とを特定し、第1の領域に対応する第1の部分画像データと第2の領域に対応する第2の部分画像データとを生成する部分画像生成部と、これらの部分画像データに基づいて第1の観察画像データ及び第2の部分画像データを生成する観察画像生成部と、第1の観察画像データ及び第2の観察画像データに基づいて試料Sの解析を行う解析部と、を備える。【選択図】図1