公开(公告)号：GR3032519T3

公开(公告)日：2000-05-31

申请号：GR20000400215

申请日：2000-01-31

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JOERG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04

Abstract: Cyclohexane derivs. of formula (I), and their salts, are new. R = O-(3-5C)alkyl-R , in which the alkyl component is straight, branched or cyclic; R = phenyl (opt. 4-substd. by F, Cl or Me); and R , R = H or OH.

公开(公告)号：AT187454T

公开(公告)日：1999-12-15

申请号：AT95106760

申请日：1995-05-04

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JOERG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04

Abstract: Cyclohexane derivs. of formula (I), and their salts, are new. R = O-(3-5C)alkyl-R , in which the alkyl component is straight, branched or cyclic; R = phenyl (opt. 4-substd. by F, Cl or Me); and R , R = H or OH.

公开(公告)号：CZ9501195A3

公开(公告)日：1995-12-13

申请号：CZ119595

申请日：1995-05-09

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JORG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04 ,  A61K31/44 ,  C07D317/02

CPC classification number: C07D471/04

公开(公告)号：DE4416433A1

公开(公告)日：1995-11-16

申请号：DE4416433

申请日：1994-05-10

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JOERG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04 ,  C07D317/72 ,  A61K31/44

Abstract: Cyclohexane derivs. of formula (I), and their salts, are new. R = O-(3-5C)alkyl-R , in which the alkyl component is straight, branched or cyclic; R = phenyl (opt. 4-substd. by F, Cl or Me); and R , R = H or OH.

公开(公告)号：CZ288443B6

公开(公告)日：2001-06-13

申请号：CZ119595

申请日：1995-05-09

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JOERG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04

Abstract: In the present invention, there are disclosed cyclohexane derivatives of the general formula I, in which Re2, Re4 and Re5 have specific meaning. These compounds can be used as medicaments for treating diseases connected with increased activity of glucose-6-phosphatase system, for instance for treating diabetes mellitus type II.

公开(公告)号：DK0682024T3

公开(公告)日：2000-05-22

申请号：DK95106760

申请日：1995-05-04

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JOERG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04

Abstract: Cyclohexane derivs. of formula (I), and their salts, are new. R = O-(3-5C)alkyl-R , in which the alkyl component is straight, branched or cyclic; R = phenyl (opt. 4-substd. by F, Cl or Me); and R , R = H or OH.

公开(公告)号：ES2141276T3

公开(公告)日：2000-03-16

申请号：ES95106760

申请日：1995-05-04

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JORG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04

Abstract: Cyclohexane derivs. of formula (I), and their salts, are new. R = O-(3-5C)alkyl-R , in which the alkyl component is straight, branched or cyclic; R = phenyl (opt. 4-substd. by F, Cl or Me); and R , R = H or OH.

公开(公告)号：CZ119595A3

公开(公告)日：1995-12-13

申请号：CZ119595

申请日：1995-05-09

Applicant: HOECHST AG

Inventor： HEMMERLE HORST DR ,  SCHUBERT GERRIT DR ,  BURGER HANS-JORG DR ,  HERLING ANDREAS DR ,  EFENDIC SUAD PROF DR

IPC: A61K31/435 ,  A61K31/4353 ,  A61K31/52 ,  A61P1/16 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07D221/00 ,  C07D235/00 ,  C07D239/00 ,  C07D471/04 ,  C07D317/02 ,  A61K31/44

Abstract: Cyclohexane derivs. of formula (I), and their salts, are new. R = O-(3-5C)alkyl-R , in which the alkyl component is straight, branched or cyclic; R = phenyl (opt. 4-substd. by F, Cl or Me); and R , R = H or OH.