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公开(公告)号:BG45856A3
公开(公告)日:1989-08-15
申请号:BG7844087
申请日:1987-02-11
Applicant: HOECHST AG
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公开(公告)号:CS545888A2
公开(公告)日:1990-06-13
申请号:CS545888
申请日:1988-08-04
Applicant: HOECHST AG
Inventor: DURCKHEIMER WALTER DR , SELIGER HUBERT , DOST GUNTER DR , CHATTERJEE SUGATA , DESIKAN KALYANPURAM R , RUPP RICHARD H DR , GANGULI BIMAL N DR , FRANCO CHRISTOPHER M
Abstract: Streptogramin B metal complexes, especially the Cu, Zn and Mn complexes of etamycin, are valuable production promoters in livestock nutrition. They are obtained by reacting neoviridogriseins with metal salts in solution and subsequent neutralisation with bases.
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3.
公开(公告)号:HU199168B
公开(公告)日:1990-01-29
申请号:HU377887
申请日:1987-08-27
Applicant: HOECHST AG
Inventor: FRANCO CHRISTOPHER M , GOUKANAPALLI , GANGULI BIMAL N , KOGLER HERBERT , GANDHI JULIA , CHATTERJEE SUGATA , RUPP RICHARD H , FEHLHABER HANS-WOLFRAM
Abstract: The macrolide antibiotic is swalpamycin and is prepared using a Streptomyces species and is used as medicament for the treatment of infections caused by bacteria, mycoplasmas and actinomycetes.
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4.
公开(公告)号:HUT46075A
公开(公告)日:1988-09-28
申请号:HU377887
申请日:1987-08-27
Applicant: HOECHST AG
Inventor: FRANCO CHRISTOPHER M , GANDHI JULIA , REDDY GOUKANAPALLI CH , CHATTERJEE SUGATA , GANGULI BIMAL N , RUPP RICHARD H , KOGLER HERBERT , FEHLHABER HANS-WOLFRAM
Abstract: The macrolide antibiotic is swalpamycin and is prepared using a Streptomyces species and is used as medicament for the treatment of infections caused by bacteria, mycoplasmas and actinomycetes.
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公开(公告)号:HU197772B
公开(公告)日:1989-05-29
申请号:HU56587
申请日:1987-02-13
Applicant: HOECHST AG
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公开(公告)号:HUT46076A
公开(公告)日:1988-09-28
申请号:HU56587
申请日:1987-02-13
Applicant: HOECHST AG
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公开(公告)号:HUT43641A
公开(公告)日:1987-11-30
申请号:HU480285
申请日:1985-12-16
Applicant: HOECHST AG
Inventor: FRANCO CHRISTOPHER M , DESIKAN KALYANAPURAM R , KRAEMER HANS P , MUKHOPADHYAY TRIPTIKUMAR , GANGULI BIMAL N , FEHLHABER HANS-WOLFRAM
IPC: C07C50/36 , A61K31/12 , A61K31/65 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P31/04 , A61P35/00 , C07C45/00 , C07C50/38 , C07C67/00 , C07H15/252 , C12P15/00 , C12P19/56 , C12R1/465 , C12P29/00 , A61K31/71
Abstract: 1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof. 1. Claims for the contracting State AT A process for the preparation of compounds of the Formula I see diagramm : EP0186807,P11,F1 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof, which comprises fermentation of the microorganism Streptomyces purpurascens DSM 2658 in a customary manner under aerobic conditions, in the presence of a nutrient medium, addition of a chemical inhibitor after a particular fermentation time, and isolation, from the culture liquid and the mycelium, of the compounds which have been formed, using organic solvents followed by chromatography in a customary manner.
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公开(公告)号:CS8805458A2
公开(公告)日:1990-06-13
申请号:CS545888
申请日:1988-08-04
Applicant: HOECHST AG
Inventor: DURCKHEIMER WALTER DR , SELIGER HUBERT , DOST GUNTER DR , CHATTERJEE SUGATA , DESIKAN KALYANPURAM R , RUPP RICHARD H DR , GANGULI BIMAL N DR , FRANCO CHRISTOPHER M
CPC classification number: C07K7/06 , A23K20/195 , A61K38/00
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公开(公告)号:HUT50361A
公开(公告)日:1990-01-29
申请号:HU54389
申请日:1989-02-03
Applicant: HOECHST AG
Inventor: FRANCO CHRISTOPHER M , CHATTERJEE SUGATA , VIJAYAKUMAR ERRA K , GANGULI BIMAL N , RUPP RICHARD H
IPC: A61K35/74 , A61K38/00 , A61P31/04 , C07K14/005 , C07K14/195 , C07K14/41 , C12N1/20 , C12P1/06 , C12P21/00 , C12R1/465 , A61K37/02
Abstract: Cammunocin, an active substance which can be obtained by cultivation of Streptomyces species Y-84,36210 (DSM 4329), has antibiotic and immunosuppressant activity.
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10.
公开(公告)号:HU197596B
公开(公告)日:1989-04-28
申请号:HU480285
申请日:1985-12-16
Applicant: HOECHST AG
Inventor: FRANCO CHRISTOPHER M , MUKHOPADHYAY TRIPTIKUMAR , DESIKAN KALYANAPURAM R , GANGULI BIMAL N , KRAEMER HANS P , FEHLHABER HANS-WOLFRAM
IPC: C07C50/36 , A61K31/12 , A61K31/65 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P31/04 , A61P35/00 , C07C45/00 , C07C50/38 , C07C67/00 , C07H15/252 , C12P15/00 , C12P19/56 , C12R1/465 , C12P29/00 , A61K31/71
Abstract: 1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE A Compound of the formula I see diagramm : EP0186807,P11,F2 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof. 1. Claims for the contracting State AT A process for the preparation of compounds of the Formula I see diagramm : EP0186807,P11,F1 in which R represents a sugar combination of the composition Roa-dF-Rod or Roa-Rod-Rod, where Roa represents rhodosamine, dF represents deoxyfucose and Rod represents rhodinose, and the physiologically acceptable acid addition salts thereof, which comprises fermentation of the microorganism Streptomyces purpurascens DSM 2658 in a customary manner under aerobic conditions, in the presence of a nutrient medium, addition of a chemical inhibitor after a particular fermentation time, and isolation, from the culture liquid and the mycelium, of the compounds which have been formed, using organic solvents followed by chromatography in a customary manner.
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