公开(公告)号：DE2519036A1

公开(公告)日：1976-11-11

申请号：DE2519036

申请日：1975-04-29

Applicant: HOECHST AG

Inventor： HILLE ERNST DR ,  RUECK RUDOLF DR

IPC: C07C231/00 ,  C07C20060101 ,  C07C67/00 ,  C07C231/04 ,  C07C231/14 ,  C07C233/78 ,  C07C103/375 ,  C07C103/34

公开(公告)号：CH608786A5

公开(公告)日：1979-01-31

申请号：CH515576

申请日：1976-04-23

Applicant: HOECHST AG

Inventor： HILLE ERNST DR ,  RUECK RUDOLF DR

IPC: C07C231/00 ,  C07C20060101 ,  C07C67/00 ,  C07C231/04 ,  C07C231/14 ,  C07C233/78 ,  C07C103/375 ,  C07C103/34

公开(公告)号：DE2240849A1

公开(公告)日：1974-03-14

申请号：DE2240849

申请日：1972-08-19

Applicant: HOECHST AG

Inventor： KUEMMERLE KURT DR ,  ALBERS ARNOLD DR ,  HILLE ERNST DR ,  HEISE HARTMUT DR

IPC: C08G18/48 ,  C07C85/10

Abstract: Title cpds are prepared by hydrogenating the corresp. nitrobenzenes in aq. phase, using Ni catalysts, and adjusting the pH to 6-7.5 by addn. of oxyacids of 3-or 5-valent P, or of B, CO2 or low-mol. carboxylic acids and strong bases, or the corresp. salts; the additives are metered in such a way that the pH does not fall below the above limit. Nitrobenzenes carrying the above substits. cannot be hydrogenated by previous methods. Only 0.01-10 wt. % Ni catalyst is needed. Lower temps., e.g. 20-120 degrees C, can be used. Aminoacids have esp. strong stabilising effect on the pH.

公开(公告)号：CH626326A5

公开(公告)日：1981-11-13

申请号：CH281777

申请日：1977-03-07

Applicant: HOECHST AG

Inventor： KUEMMERLE KURT DR ,  HEISE HARTMUT DR ,  HILLE ERNST DR

IPC: C07B61/00 ,  B01J23/00 ,  B01J23/40 ,  B01J23/74 ,  B01J31/00 ,  B01J31/02 ,  C07C20060101 ,  C07C67/00 ,  C07C231/00 ,  C07C231/12 ,  C07C235/16 ,  C07C235/24 ,  C07C103/34

Abstract: The liquid-phase catalytic hydrogenation of N-acetoacetyl arylamides to yield 3-hydroxybutyric acid arylamides proceeds much faster when amines, phosphines or trialkylphosphates are added. Thus, even with lower hydrogen pressures and at lower temperatures with a lower catalyst concentration, shorter reaction times are sufficient.

公开(公告)号：CH603597A5

公开(公告)日：1978-08-31

申请号：CH515476

申请日：1976-04-23

Applicant: HOECHST AG

Inventor： SAHM WILFRIED DR ,  HILLE ERNST DR ,  SCHILLER WOLFGANG

IPC: C07D235/26

Abstract: 5-Acetoacetylamino benzimidazolone-(2) is obtained in high yield and excellent purity by reacting diketene with the aqueous solution of a salt of 5-amino-benzimidazolone-(2) and an acid having a pKa value of 1 to 7, preferably in the presence of an antioxidant and/or a reducing agent.

公开(公告)号：CH594600A5

公开(公告)日：1978-01-13

申请号：CH1513475

申请日：1975-11-21

Applicant: HOECHST AG

Inventor： PASZTHORY EMMERICH DR ,  MEES BERNHARD DR ,  HILLE ERNST DR

IPC: C07B61/00 ,  C07C20060101 ,  C07C67/00 ,  C07C213/00 ,  C07C213/02 ,  C07C217/84 ,  C07C93/14

Abstract: 1527892 Preparation of 4-chloro-2,5-dimethoxyaniline HOECHST AG 25 Nov 1975 [25 Nov 1974] 48445/75 Heading C2C 4 - Chloro - 2,5 - dimethoxyaniline or a salt thereof is obtained by treating a mixture comprising water and particles of 4-chloro-2,5- dimethoxynitrobenzene having an average size of less than 100 microns with hydrogen in the presence of a nickel catalyst, and if desired, converting the 4-chloro-2,5-dimethoxyaniline to a salt thereof.

公开(公告)号：DE2609835A1

公开(公告)日：1977-09-22

申请号：DE2609835

申请日：1976-03-10

Applicant: HOECHST AG

Inventor： KUEMMERLE KURT DR ,  HEISE HARTMUT DR ,  HILLE ERNST DR

IPC: C07B61/00 ,  B01J23/00 ,  B01J23/40 ,  B01J23/74 ,  B01J31/00 ,  B01J31/02 ,  C07C20060101 ,  C07C67/00 ,  C07C231/00 ,  C07C231/12 ,  C07C235/16 ,  C07C235/24 ,  C07C103/34

Abstract: The liquid-phase catalytic hydrogenation of N-acetoacetyl arylamides to yield 3-hydroxybutyric acid arylamides proceeds much faster when amines, phosphines or trialkylphosphates are added. Thus, even with lower hydrogen pressures and at lower temperatures with a lower catalyst concentration, shorter reaction times are sufficient.

公开(公告)号：DE2518984B1

公开(公告)日：1976-10-21

申请号：DE2518984

申请日：1975-04-29

Applicant: HOECHST AG

Inventor： PASZTHORY EMMERICH DR ,  HILLE ERNST DR ,  SEIFERT KARL-GERHARD DR ,  ZIMMERMANN VINCENZ

IPC: C07C235/80 ,  C07C67/00 ,  C07C231/00 ,  C07C231/04 ,  C07C233/16 ,  C07C103/38

Abstract: N-acetoacetyl-2,5-dimethoxy-4-chloroanilide is obtained in high yield and purity by suspending 2,5-dimethoxy-4-chloroaniline in water and adding the complete amount of diketene necessary altogether at the beginning of the reaction. The product is obtained in a purity allowing its use as an azoic coupling component without purification.