公开(公告)号：US3775468A

公开(公告)日：1973-11-27

申请号：US3775468D

申请日：1970-05-05

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: C07C265/04 ,  C07D205/08 ,  C07C119/04

CPC classification number: C07C265/04 ,  C07B2200/07 ,  C07C263/08 ,  C07C265/06 ,  C07D205/08

Abstract: OPTICALLY ACTIVE B-HALOGENOALKYL ISOCYANATES ARE OBTAINED BY RE-ARRANGEMENT OF N-HALOGENOAZETIDINONES-(2) EFFECTED BY RADICAL-FORMING CATALYSTS IN THE PRESENCE OF UNSATURATED COMPOUNDS AS CO-CTALYSTS. DUE TO THEIR GROUPS OF DIFFERENT DEGREES OF REACTIVITY THE PRODUCTS ARE USEFUL INTERMEDIATES FOR THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS. THEY ARE, FURTHERMORE, USEFUL FOR SPLITTING RACEMIC MIXTURES.

公开(公告)号：US3717556A

公开(公告)日：1973-02-20

申请号：US3717556D

申请日：1970-06-05

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: B01J19/08 ,  C07C263/12 ,  C07C265/04 ,  C07D205/08 ,  B01J1/10 ,  C07C119/04

CPC classification number: B01J19/082 ,  C07C263/08 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/18 ,  C07D205/08 ,  C07C265/04 ,  C07C265/10

Abstract: N-halogeno-alkyl- Beta -lactams are rearranged into Beta halogeno-alkyl-isocyanates by contacting them with unsaturated organic compounds, optionally under irradiation. The products are highly reactive and useful for the synthesis of heterocyclic compounds.

Abstract translation: N-卤代烷基-β-内酰胺通过与不饱和有机化合物接触，任选地在照射下将其重新排列成β-卤代烷基异氰酸酯。 该产物具有高反应性，可用于杂环化合物的合成。

公开(公告)号：US3842109A

公开(公告)日：1974-10-15

申请号：US29880572

申请日：1972-10-06

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: C07C265/04 ,  C07D205/12 ,  C07C119/04

CPC classification number: C07D205/12 ,  C07C263/08 ,  C07C2601/08 ,  C07C2601/18 ,  C07C265/04 ,  C07C265/10

Abstract: 1. A PROCESS FOR THE PREPARATION OF A B-HALOALKYLISOCYANATE OF THE FORMULA X-C(-R3)(-R4)-C(-R1)(-R2)-N=C=O WHEREIN X IS CHLORINE OR BROMINE AND R1,R3 AND R4, TAKEN ALONE, ARE HYDROGEN, ALKYL OF 1 TO 13 CARBONA TOMS, ALKENYL OF 2 TO 13 CARBON ATOMS, CHLOROALKYL OF 1 TO 13 CARBON ATOMS, BROMOALKYL OF 1 TO 13 CARBON ATOMS, CYCLOALKYL OF 5 TO 6 CARBON ATOMS, OR PHENYL, AND WHEREIN R1, T2, R3 AND R4, TAKEN PAIRWISE ARE ALKYLENE OR ALKENYLENE OF 2 TO 6 CARBON ATOMS OR PART OF A BICYCLIC OR TRICYCLIC CARBOXYLIC SATURATED OR MONO-SATURATED RING SYSTEM OF UP TO 13 CARBON ATOMS, WHICH PROCESS COMPRISES CONTACTING, AT A TEMPERATURE OF ABOUT-30*C. TO ABOUT +250* C., A LACTAM OF THE FORMULA X-N

公开(公告)号：ZA7906651B

公开(公告)日：1981-05-27

申请号：ZA7906651

申请日：1979-12-07

Applicant: HOECHST AG

Inventor： KAMPE K ,  GRANZER E

IPC: A61K31/415 ,  A61K31/505 ,  A61P3/04 ,  A61P3/06 ,  C07D239/48 ,  C07D403/04 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D

CPC classification number: C07D239/48 ,  C07C255/00 ,  Y10S514/909

公开(公告)号：ZA703938B

公开(公告)日：1972-06-28

申请号：ZA703938

申请日：1970-06-10

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: B01J19/08 ,  C07C263/12 ,  C07C265/04 ,  C07D205/08 ,  C07C

公开(公告)号：ZA796651B

公开(公告)日：1981-05-27

申请号：ZA796651

申请日：1979-12-07

Applicant: HOECHST AG

Inventor： KAMPE K ,  GRANZER E

IPC: A61K31/415 ,  A61K31/505 ,  A61P3/04 ,  A61P3/06 ,  C07D239/48 ,  C07D403/04 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D

Abstract: What is disclosed are 4-amino-2-ureido (or -thioureido)-pyrimidine-5-carboxylic acid anilides of the formula further defined in the specification, and physiologically acceptable acid addition salts thereof, methods for treating adiposity and disturbances of the lipometabolism with these compounds or salts, and pharmaceutical compositions containing these compounds or salts and useful for inducing anorexia or affecting the lipometabolism.

公开(公告)号：DK124077B

公开(公告)日：1972-09-11

申请号：DK213568

申请日：1968-05-08

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: C07C263/08 ,  C07C263/12 ,  C07C265/04 ,  C07D205/08 ,  C07D205/12 ,  C07C119/04

公开(公告)号：DK127779B

公开(公告)日：1974-01-07

申请号：DK99970

申请日：1970-02-27

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: C07C263/08 ,  C07C263/12 ,  C07C265/04 ,  C07D205/08 ,  C07D205/12 ,  C07C119/04

公开(公告)号：DK123594B

公开(公告)日：1972-07-10

申请号：DK588069

申请日：1969-11-06

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: C07C265/04 ,  C07D205/08 ,  C07C119/04 ,  C07B19/00

公开(公告)号：ZA7003938B

公开(公告)日：1972-06-28

申请号：ZA7003938

申请日：1970-06-10

Applicant: HOECHST AG

Inventor： KAMPE K

IPC: B01J19/08 ,  C07C263/12 ,  C07C265/04 ,  C07D205/08 ,  C07C

CPC classification number: B01J19/082 ,  C07C263/08 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/18 ,  C07D205/08 ,  C07C265/04 ,  C07C265/10