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公开(公告)号：NO924806A
公开(公告)日：1993-06-15
申请号：NO924806
申请日：1992-12-11
Applicant: HOECHST AG
Inventor： ENGLERT HEINRICH , MANIA DIETER , KIBAT PAUL-GERHARD , GEHRING DORIS , PAULUS ERICH
IPC: A61K31/35 , A61K9/12 , A61K31/352 , A61K31/353 , A61K31/40 , A61K31/4025 , A61K31/445 , A61P11/00 , A61P11/06 , A61P11/08 , C07D207/12 , C07D311/68 , C07D311/74 , C07D405/04 , A61K31/395
CPC classification number: C07D405/04
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2.发明专利
公开(公告)号：ZA9102702B
公开(公告)日：1991-12-24
申请号：ZA9102702
申请日：1991-04-11
Applicant: HOECHST AG
Inventor： KIBAT PAUL-GERHARD , PAUL-GERHARD KIBAT , SANDOW JUERGEN KURT , JUERGEN KURT SANDOW
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3.发明专利
公开(公告)号：CA2040237A1
公开(公告)日：1991-10-13
申请号：CA2040237
申请日：1991-04-11
Applicant: HOECHST AG
Inventor： KIBAT PAUL-GERHARD , SANDOW JURGEN K
Abstract: of the disclosure: HOE 90/F 112 Long-acting liposome peptide pharmaceutical products and processes for the preparation thereof Liposome products for peptides with extended peptide release are described. The peptides have a molecular weight between 500 and 10000, and the phospholipid component of the liposome membrane has a phase-transition temperature of at least 20.degree.C and contains mainly saturated fatty acids. The activity persists for more than 14 days after s.c. or i.m. injection. Processes for preparing these liposome products are also described.
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公开(公告)号：FI925618A
公开(公告)日：1993-06-15
申请号：FI925618
申请日：1992-12-10
Applicant: HOECHST AG
Inventor： ENGLERT HEINRICH , MANIA DIETER , KIBAT PAUL-GERHARD , GEHRING DORIS , PAULUS ERICH
IPC: A61K31/35 , A61K9/12 , A61K31/352 , A61K31/353 , A61K31/40 , A61K31/4025 , A61K31/445 , A61P11/00 , A61P11/06 , A61P11/08 , C07D207/12 , C07D311/68 , C07D311/74 , C07D405/04
Abstract: The invention relates to ethanol adducts of the compounds of the formula I I to a process for their preparation and to their use as inhalants in diseases, in particular in asthma.
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公开(公告)号：NZ237787A
公开(公告)日：1992-03-26
申请号：NZ23778791
申请日：1991-04-10
Applicant: HOECHST AG
Inventor： KIBAT PAUL-GERHARD , SANDOW JURGEN KURT
IPC: A61K9/127 , A61K38/00 , A61K38/04 , A61K38/09 , A61K38/55 , A61K38/58 , A61K37/00 , A61K37/24 , A61K37/64
Abstract: Liposome compositions for peptides with prolonged release of peptides are described. The peptides have a molecular weight between 500 and 10000, and the phospholipid component of the liposome membrane has a phase transition temperature of at least 20 DEG C and contains predominantly saturated fatty acids. The activity persists for more than 14 days after s.c. or i.m. injection. Also described are methods for preparing these liposome compositions.
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Patent Agency Ranking6.发明专利
公开(公告)号：ZA912702B
公开(公告)日：1991-12-24
申请号：ZA912702
申请日：1991-04-11
Applicant: HOECHST AG
Inventor： KIBAT PAUL-GERHARD , PAUL-GERHARD KIBAT , SANDOW JUERGEN KURT , JUERGEN KURT SANDOW
Abstract: Liposome compositions for peptides with prolonged release of peptides are described. The peptides have a molecular weight between 500 and 10000, and the phospholipid component of the liposome membrane has a phase transition temperature of at least 20 DEG C and contains predominantly saturated fatty acids. The activity persists for more than 14 days after s.c. or i.m. injection. Also described are methods for preparing these liposome compositions.
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7.发明专利
公开(公告)号：AU653874B2
公开(公告)日：1994-10-13
申请号：AU3017192
申请日：1992-12-11
Applicant: HOECHST AG
Inventor： ENGLERT HEINRICH , MANIA DIETER , KIBAT PAUL-GERHARD , GEHRING DORIS , PAULUS ERICH
IPC: A61K31/35 , A61K9/12 , A61K31/352 , A61K31/353 , A61K31/40 , A61K31/4025 , A61K31/445 , A61P11/00 , A61P11/06 , A61P11/08 , C07D207/12 , C07D311/68 , C07D311/74 , C07D405/04
Abstract: The invention relates to ethanol adducts of the compounds of the formula I I to a process for their preparation and to their use as inhalants in diseases, in particular in asthma.
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8.发明专利
公开(公告)号：CA2085166A1
公开(公告)日：1993-06-15
申请号：CA2085166
申请日：1992-12-11
Applicant: HOECHST AG
Inventor： ENGLERT HEINRICH , MANIA DIETER , KIBAT PAUL-GERHARD , GEHRING DORIS , PAULUS ERICH
IPC: A61K31/35 , A61K9/12 , A61K31/352 , A61K31/353 , A61K31/40 , A61K31/4025 , A61K31/445 , A61P11/00 , A61P11/06 , A61P11/08 , C07D207/12 , C07D311/68 , C07D311/74 , C07D405/04
Abstract: HOE 91/F 390 : Ethanol adducts of 6-sulfonyl-substituted 3-hydroxy-chromans and their use as inhalants in diseases The invention relates to ethanol adducts of the compounds of the formula I I to a process for their preparation and to their use as inhalants in diseases, in particular in asthma.
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公开(公告)号：NO922022A
公开(公告)日：1992-11-25
申请号：NO922022
申请日：1992-05-22
Applicant: HOECHST AG
Inventor： KRONE VOLKER , MAGERSTAEDT MICHAEL , WALCH AXEL , KIBAT PAUL-GERHARD
IPC: A61K31/765 , A61K9/16 , A61K9/20 , A61K9/22 , A61K31/785 , A61K31/795 , A61K49/22 , C08G63/16 , C08G63/60 , C08G63/66 , C08G63/68 , C08G69/26 , C08G75/00 , C08G75/26 , C08G63/42 , A61K49/00 , C08G63/40 , C08G63/672
CPC classification number: C08G63/66 , A61K9/1641 , A61K9/1647 , A61K9/204 , A61K9/2045 , A61K49/225 , C08G63/16 , C08G63/60 , C08G63/68 , C08G69/26
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10.发明专利
公开(公告)号：HU911185D0
公开(公告)日：1991-10-28
申请号：HU118591
申请日：1991-04-11
Applicant: HOECHST AG
Inventor： KIBAT PAUL-GERHARD , SANDOW JUERGEN KURT
Abstract: Liposome compositions for peptides with prolonged release of peptides are described. The peptides have a molecular weight between 500 and 10000, and the phospholipid component of the liposome membrane has a phase transition temperature of at least 20 DEG C and contains predominantly saturated fatty acids. The activity persists for more than 14 days after s.c. or i.m. injection. Also described are methods for preparing these liposome compositions.
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