公开(公告)号：US3502666A

公开(公告)日：1970-03-24

申请号：US3502666D

申请日：1967-11-16

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  SCHMITT KARL ,  SEIDL GUNTHER ,  HOFFMANN IRMGARD

IPC: A61K31/00 ,  C07D93/08 ,  A61K27/00

CPC classification number: A61K31/00

公开(公告)号：AU4106085A

公开(公告)日：1985-10-17

申请号：AU4106085

申请日：1985-04-10

Applicant: HOECHST AG

Inventor： KRUSE HANSJORG ,  KUCH HEINZ

IPC: A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61P25/08 ,  C07D209/34 ,  C07D209/38 ,  A61K31/405 ,  C07D405/12

公开(公告)号：FI821218A0

公开(公告)日：1982-04-06

申请号：FI821218

申请日：1982-04-06

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  KRUSE HANSJOERG

IPC: A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61P25/28 ,  C07D209/34 ,  C07D209/36 ,  C07D209/38 ,  C07D295/185 ,  C07D

Abstract: Oxindole derivatives of the general formula I (I) are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various animal models.

公开(公告)号：CA966483A

公开(公告)日：1975-04-22

申请号：CA139384

申请日：1972-04-11

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  HOFFMANN IRMGARD

IPC: C07D243/12 ,  C07F9/53 ,  C07F9/645

Abstract: Dialkylphosphinylalkylene-substituted 1,5-benzodiazepines useful as medicaments in the treatment of psychic diseases are obtainable by reacting the corresponding benzodiazepines with a dialkyl-phosphinylalkyl halide or by reacting a 2-dialkyl-phosphinylalkylaminodiphenylamine with a malonic acid dihalide or alkylmalonic acid dihalide.

公开(公告)号：NO821158L

公开(公告)日：1982-10-11

申请号：NO821158

申请日：1982-04-06

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  KRUSE HANSJOERG

IPC: A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61P25/28 ,  C07D209/34 ,  C07D209/36 ,  C07D209/38 ,  C07D295/185 ,  C07D

Abstract: Oxindole derivatives of the general formula I (I) are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various animal models.

公开(公告)号：CA884324A

公开(公告)日：1971-10-26

申请号：CA884324D

Applicant: HOECHST AG

Inventor： HOFFMANN IRMGARD ,  KUCH HEINZ ,  SCHMITT KARL ,  SEIDL GUNTHER

公开(公告)号：FI821218L

公开(公告)日：1982-10-10

申请号：FI821218

申请日：1982-04-06

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  KRUSE HANSJOERG

IPC: A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61P25/28 ,  C07D209/34 ,  C07D209/36 ,  C07D209/38 ,  C07D295/185 ,  C07D

Abstract: Oxindole derivatives of the general formula I (I) are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various animal models.

公开(公告)号：RO63622A

公开(公告)日：1978-08-15

申请号：RO7819272

申请日：1972-04-12

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  HOFFMANN IRMGARD

IPC: C07F9/53 ,  C07D243/12 ,  C07F9/645

Abstract: Dialkylphosphinylalkylene-substituted 1,5-benzodiazepines useful as medicaments in the treatment of psychic diseases are obtainable by reacting the corresponding benzodiazepines with a dialkyl-phosphinylalkyl halide or by reacting a 2-dialkyl-phosphinylalkylaminodiphenylamine with a malonic acid dihalide or alkylmalonic acid dihalide.

公开(公告)号：CS181707B2

公开(公告)日：1978-03-31

申请号：CS229972

申请日：1972-04-06

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  HOFFMANN IRMGARD

IPC: C07D243/12 ,  C07F9/53 ,  C07F9/645

Abstract: Dialkylphosphinylalkylene-substituted 1,5-benzodiazepines useful as medicaments in the treatment of psychic diseases are obtainable by reacting the corresponding benzodiazepines with a dialkyl-phosphinylalkyl halide or by reacting a 2-dialkyl-phosphinylalkylaminodiphenylamine with a malonic acid dihalide or alkylmalonic acid dihalide.

公开(公告)号：CS181744B2

公开(公告)日：1978-03-31

申请号：CS499476

申请日：1972-04-06

Applicant: HOECHST AG

Inventor： KUCH HEINZ ,  HOFFMANN IRMGARD

IPC: C07D243/12 ,  C07F9/53 ,  C07F9/645

Abstract: Dialkylphosphinylalkylene-substituted 1,5-benzodiazepines useful as medicaments in the treatment of psychic diseases are obtainable by reacting the corresponding benzodiazepines with a dialkyl-phosphinylalkyl halide or by reacting a 2-dialkyl-phosphinylalkylaminodiphenylamine with a malonic acid dihalide or alkylmalonic acid dihalide.