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    MEDICINAL COMPOSITION AND ITS USE AS ANTIDEPRESSIVE AGENT
    5.
    发明专利
    MEDICINAL COMPOSITION AND ITS USE AS ANTIDEPRESSIVE AGENT 未知

    公开(公告)号：CA1102242A

    公开(公告)日：1981-06-02

    申请号：CA304493

    申请日：1978-05-31

    Applicant: HOECHST AG

    Inventor： SCHMITT KARL ,  HOFFMANN IRMGARD ,  FUELBERTH WERNER ,  STAMMBERGER WILLI

    IPC: A61K31/47 ,  A61K31/55 ,  A61P25/24 ,  A61P25/26

    Abstract: MEDICINAL COMPOSITION AND ITS USE AS ANTIDEPRESSIVE AGENT of the disclosure: Medicinal composition containing compounds of the general formula I (I) in which R1, R3 and R4, which may be identical or different, and represent hydrogen atoms or lower alkyl or aralkyl groups, and R2 and R?, which may be identical or different, represent hydrogen or halogen atoms, hydroxy or trifluoromethyl groups or lower alkyl alkoxy or aralkoxy groups, it also being possible that that two adjacent radicals form an alkylene-dioxy radical, and R5 represents a hydrogen or halogen atom, a hydroxy, trifluoromethyl or nitro group or a lower alkyl, alkoxy or aralkoxy radical, and their salts with acids (active substance A) and 7-chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4 (3H,5H)-dione (active substance B), and its use as antidepressive agent.

    ANTIDEPRESSANT COMPOSITION
    7.
    发明专利
    ANTIDEPRESSANT COMPOSITION 未知

    公开(公告)号：AU3670478A

    公开(公告)日：1979-12-06

    申请号：AU3670478

    申请日：1978-05-31

    Applicant: HOECHST AG

    Inventor： SCHMITT KARL ,  SCHMIDT KARL ,  HOFFMANN IRMGARD ,  FULBERTH WERNER ,  STAMMBERGER WILLI

    IPC: A61K31/47 ,  A61K31/55 ,  A61P25/24 ,  A61P25/26

    Abstract: What is disclosed are medicinal compositions, useful as anti-depressive agents, containing a compound of the formula; (I) in which R1, R3 and R4, which may be identical or different, and represent hydrogen atoms or lower alkyl or aralkyl groups, and R2 and R2', which may be identical or different, represent hydrogen or halogen atoms, hydroxy or trifluoromethyl groups or lower alkyl, alkoxy or aralkoxy groups, it also being possible that two adjacent radicals form an alkylene-dioxy radical, and R5 represents a hydrogen or halogen atom, a hydroxy, trifluoromethyl or nitro group or a lower alkyl, alkoxy or aralkoxy radical, and their salts with acids (active substance A) together with 7-chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4 (3H,5H)-dione (active substance B), and their use as antidepressive agent.

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