公开(公告)号：GR3007608T3

公开(公告)日：1993-08-31

申请号：GR930400361

申请日：1993-04-09

Applicant: HOECHST AG

Inventor： BREMER KARL-HEINZ DR ,  KUHLMANN LUDWIG DR ,  SCHWARZ ALEXANDER DR ,  STEINSTRAESSER AXEL DR DR

IPC: A61K39/395 ,  A61K51/00 ,  A61K51/10 ,  A61K51/12 ,  G01N33/534 ,  A61K49/02

Abstract: The method entails an organ-specific substance, an organ-specific substance which has been pretreated or coupled to a complexing agent for technetium-99m being mixed with pertechnetat-99m and a complex-stabilised reducing agent.

公开(公告)号：DE3237573A1

公开(公告)日：1984-04-12

申请号：DE3237573

申请日：1982-10-09

Applicant: HOECHST AG

Inventor： KLEINER HANS-JOERG DR ,  KLOSS GERHARD DR ,  MOLTER MICHAEL DR ,  SCHWARZ ALEXANDER DR ,  THAMM HELMUT DR

IPC: A61K51/00 ,  A61K51/04 ,  C07F9/38 ,  A61K49/02

Abstract: A diagnostic agent for the visualization of RES-containing organs or of lymph vessels, containing 99mTc triphosphonates or tetraphosphonates in physiologic saline, and a process for their preparation.

公开(公告)号：ES2053515T5

公开(公告)日：1996-06-16

申请号：ES87118142

申请日：1987-12-08

Applicant: HOECHST AG

Inventor： BREMER KARL-HEINZ DR ,  KUHLMANN LUDWIG DR ,  SCHWARZ ALEXANDER DR ,  STEINSTRASSER AXEL DR DR

IPC: A61K39/395 ,  A61K51/00 ,  A61K51/10 ,  A61K51/12 ,  G01N33/534

Abstract: The method entails an organ-specific substance, an organ-specific substance which has been pretreated or coupled to a complexing agent for technetium-99m being mixed with pertechnetat-99m and a complex-stabilised reducing agent.

公开(公告)号：ES2053515T3

公开(公告)日：1994-08-01

申请号：ES87118142

申请日：1987-12-08

Applicant: HOECHST AG

Inventor： BREMER KARL-HEINZ DR ,  KUHLMANN LUDWIG DR ,  SCHWARZ ALEXANDER DR ,  STEINSTRASSER AXEL DR DR

IPC: A61K39/395 ,  A61K51/00 ,  A61K51/10 ,  A61K51/12 ,  G01N33/534 ,  A61K49/02

Abstract: The method entails an organ-specific substance, an organ-specific substance which has been pretreated or coupled to a complexing agent for technetium-99m being mixed with pertechnetat-99m and a complex-stabilised reducing agent.

公开(公告)号：GR3002968T3

公开(公告)日：1993-01-25

申请号：GR910401333

申请日：1991-10-23

Applicant: HOECHST AG

Inventor： BREMER KARL-HEINZ DR ,  KUHLMANN LUDWIG DR ,  MAGERSTAEDT MICHAEL DR ,  SCHWARZ ALEXANDER DR ,  STEINSTRAESSER AXEL DR DR

IPC: A61K51/00 ,  A61K51/04 ,  C07B31/00 ,  C07B59/00 ,  C07C67/00 ,  C07D257/02 ,  C07F13/00 ,  A61K49/02 ,  A61K43/00

公开(公告)号：AT74770T

公开(公告)日：1992-05-15

申请号：AT89105358

申请日：1989-03-25

Applicant: HOECHST AG

Inventor： SCHWARZ ALEXANDER DR ,  STEINSTRAESSER AXEL DR

IPC: A61K51/00 ,  A61K51/04 ,  A61K49/02

公开(公告)号：DE3728599A1

公开(公告)日：1988-06-23

申请号：DE3728599

申请日：1987-08-27

Applicant: HOECHST AG

Inventor： BREMER KARL-HEINZ DR ,  KUHLMANN LUDWIG DR ,  SCHWARZ ALEXANDER DR ,  STEINSTRAESSER AXEL DR DR

IPC: A61K39/395 ,  A61K51/00 ,  A61K51/10 ,  A61K51/12 ,  G01N33/534 ,  C09K3/00 ,  C07K15/06 ,  C07H23/00 ,  A61K49/02 ,  G01N33/60

Abstract: The method entails an organ-specific substance, an organ-specific substance which has been pretreated or coupled to a complexing agent for technetium-99m being mixed with pertechnetat-99m and a complex-stabilised reducing agent.

公开(公告)号：DE2755874A1

公开(公告)日：1979-06-21

申请号：DE2755874

申请日：1977-12-15

Applicant: HOECHST AG

Inventor： SCHWARZ ALEXANDER DR

IPC: A61K51/04 ,  A61K29/00

公开(公告)号：AT84725T

公开(公告)日：1993-02-15

申请号：AT87118142

申请日：1987-12-08

Applicant: HOECHST AG

Inventor： BREMER KARL-HEINZ DR ,  KUHLMANN LUDWIG DR ,  SCHWARZ ALEXANDER DR ,  STEINSTRAESSER AXEL DR DR

IPC: A61K49/02

公开(公告)号：DE3482093D1

公开(公告)日：1990-06-07

申请号：DE3482093

申请日：1984-08-21

Applicant: HOECHST AG

Inventor： SCHWARZ ALEXANDER DR

IPC: A61K51/04 ,  A61K49/02

Abstract: N-(4-Aminobenzoyl)-aspartic acid and -glutamic acid, their physiologically acceptable salts or their esters are described as stabilizers for Tc99m injection preparations which contain a tin-II compound as a reducing component and an organ-specific component, as well as the production of such injection preparations for bone scintigraphy.