公开(公告)号：DK139626C

公开(公告)日：1979-09-10

申请号：DK385873

申请日：1973-07-11

Applicant: HOECHST AG

Inventor： SOEDER A ,  NESEMANN G ,  THURM H

IPC: C07D473/04

公开(公告)号：SE400289B

公开(公告)日：1978-03-20

申请号：SE7309835

申请日：1973-07-12

Applicant: HOECHST AG

Inventor： SODER A ,  NESEMANN G ,  THURM H

IPC: A61K31/52 ,  A61K31/522 ,  A61P11/08 ,  C07D473/04 ,  C07D473/06 ,  C07D473/08 ,  C07D473/10 ,  C12P17/18

Abstract: Title cpds. of formula (I) (where >=1 of R1-R3 = 3-8C oxoalkyl with the CO gp(s) one or more C's removed from the xanthine nucleus, and the others are 1-6C alkyl). may be prepd. from the corresp. hydroxy alkyl cpds. by (a) dehydrogenation with O2 and a Gp VIII metal catalyst. (b) oxidation with Cr(VI), or (c) microbiological dehydrogenation.